Clinical case of an unusual course of coronavirus infection in patient with chronic disseminated pulmonary tuberculosis and human immunodeficiency virus infection

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Introduction: The coronavirus 2019 (COVID-19) pandemic demonstrated a negative influence on many underlying diseases, their course, and prognosis. A combined course of active tuberculosis, human immunodeficiency virus (HIV) infection, and COVID-19 is a rare case in the routine clinical practice; therefore, it is of scientific and practical interest. In a 41-year-old patient with severe chronic disseminated pulmonary tuberculosis and HIV infection, presence of tuberculosis mycobacteria, resistance to streptomycin and isoniazid, chronic respiratory failure, cachexia, and immunodeficiency, COVID-19 was manifested only by the detection of SARS-Cov-2 virus from the nasopharynx and did not influence the treatment and prognosis of tuberculosis.

Conclusion: The described case of a combination of active tuberculosis with HIV infection and COVID-19 demonstrated that effective treatment of specific tuberculosis process is quite possible.

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About the authors

Vitaly L. Dobin

Ryazan State Medical University

ORCID iD: 0000-0002-6512-558X
SPIN-code: 7954-9457
ResearcherId: S-8143-2016

Doctor of Medical Sciences, Professor, Head of the Department of Phthisiology with the course of radiation diagnostics

Russian Federation, 9, Vysokovoltnaya, Ryazan 390026

Alexei V. Gorbunov

Regional Clinical TB Dispensary

ORCID iD: 0000-0003-2915-1024

MD, phthisiatrician of the highest category

Russian Federation, 15, Golenchinskoe shosse, Ryazan 390046

Yevgeniy N. Muratov

Regional Clinical TB Dispensary

Author for correspondence.
ORCID iD: 0000-0001-7479-4972

MD, phthisiatrician of the highest category

Russian Federation, 15, Golenchinskoe shosse, Ryazan 390046


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Свидетельство о регистрации СМИ ПИ № ФС77-76803 от 24 сентября 2019 года выдано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).

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