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Morphological changesof the gutas the result of acutehemorrhage
- Issue: Vol 18, No 1 (2010)
- Pages: 25-29
- Section: Articles
- URL: https://journals.eco-vector.com/pavlovj/article/view/5222
- DOI: https://doi.org/10.17816/PAVLOVJ2010125-29
- ID: 5222
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Abstract
In experiment on rats morphological changes of the gut depending on life expectancy as the result of acute
hemorrhage have been studied. During the first day in mucous tunic of the small intestine reduction of its
thickness, desquamation and necrosis of villi were marked, in 7,4 % of cases there were erosions and ulcers. The
quantity of mast cells with degranulation attributes was increasing from 3 o'clock till 7 o'clock, eosinophilic
leukocytes - from 12 o'clock till 24 o'clock. As a result dystrophic changes in ganglion cells of vegetative nervous
textures and in smooth muscle cells of a muscle coat led to paresis of the intestine. Changes in the small intestine
were characterized by greater expressiveness of dystrophic and necrotic injuries in comparison with the large
intestine
hemorrhage have been studied. During the first day in mucous tunic of the small intestine reduction of its
thickness, desquamation and necrosis of villi were marked, in 7,4 % of cases there were erosions and ulcers. The
quantity of mast cells with degranulation attributes was increasing from 3 o'clock till 7 o'clock, eosinophilic
leukocytes - from 12 o'clock till 24 o'clock. As a result dystrophic changes in ganglion cells of vegetative nervous
textures and in smooth muscle cells of a muscle coat led to paresis of the intestine. Changes in the small intestine
were characterized by greater expressiveness of dystrophic and necrotic injuries in comparison with the large
intestine
References
- Зербино Д. Д. Методика определения «возраста» фибрина при синдроме диссеминированного внутрисосудистого свертывания крови / Д. Д. Зербино, Л. Л. Лукасевич // Арх. патологии.- 1984. - Т. 46, № 8. - С. 72-75
- Каньшина Н. Ф. Клинико-анатомические проявления поражения кишечника при шоке / Н. Ф. Каньшина, Б. Д. Даровский, О. П. Чижиков // Арх. патологии. - 1991. - Т.53, № 2. - С. 76-79.
- Причины летальных исходов при ранениях / Н. Д. Клочков [и др.] // Тр. ВМА им. С.М. Кирова. - СПб., 1993. - Т. 232. - С. 43-63.
- Повзун С. А. Важнейшие синдромы: патогенез и патологическая анатомия / С. А. Повзун. - СПб.: ООО «ИПК «КОСТА», 2009. - 480 с
- Эрозии и язвы верхних отделов желудочно-кишечного тракта у пострадавших с тяжелой сочетанной травмой / И. М. Самохвалов [и др.] // Воен.- мед. журн. - 2009. - № 3. - С. 30-34.
- Тимофеев И. В. Патология лечения: руководство для врачей / И. В. Тимофеев. - СПб.: Северо-Запад, 1999. - 656 с.
- Hemorrhagic shock induces endothelial cell apoptosis, which is mediated by factors contained in mesenteric lymph / Q. Lu [et al.] // Crit. Care Med. - 2004. - Vol. 32, № 12. - P. 2464-2470.
- The role of bacterial translocation on neutrophil activation during hemorrhagic shock in rats / T. Shimizu [et al.] // Shock. - 2001. - Vol. 16, № 1. - P. 59-63.
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