The Clinical Case Of Symptomatic Epilepsy In Newborn With Neonatal Hypoglycemic Encephalopathy
- Authors: Melashenko T.V1, Guzeva V.V1, Malekov D.A1
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Affiliations:
- St Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
- Issue: Vol 7, No 4 (2016)
- Pages: 147-152
- Section: Articles
- URL: https://journals.eco-vector.com/pediatr/article/view/5981
- DOI: https://doi.org/10.17816/PED74147-152
- ID: 5981
Cite item
Abstract
Symptomatic epilepsy is common disorder in neonatal period. One of the reasons of symptomatic epilepsy can be neonatal hypoglycemia. Hypoglycemia is the commonest metabolic disorder in neonatal period. Neonatal hypoglycemia can cause neonatal hypoglycemic encephalopathy (NHE) with damage of occipital cortex, symptomatic epilepsy in early postnatal period of life and severe neurological impairment in childhood. Early diagnosis of the NHE is possibly by using brain’s MRI and EEG in neonatal period. Presented clinical case of symptomatic epilepsy in newborn with NHE and results of his clinical examination and findings on brain’s MRI, EEG. There has been performance twice EEG recoding in the acute clinical phase of the hypoglycemic encephalopathy with video monitoring. We used multichannel EEG record in the neonatal modification. Once there has been fulfillment MRI (1,5T scanner) in early period of the case disease (after the convulsion discontinuation). We routinely used T1 weighted imaging, T2 weighted imaging, DWI and Flair. We show the correlation functional brain discharge and structural brain damages by MRI in the case of the neonatal hypoglycemic encephalopathy. The EEG recorded epileptiform activity (sharp theta-waves, spices) in central-occipital and temporal regions. We detected the changes MR-signal from central-occipital and temporal brains regions and thinning of occipital cortex with normal cortex architecture
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About the authors
Tatiana V Melashenko
St Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
Author for correspondence.
Email: melashenkotat@mail.ru
MD, PhD, Associate Professor Russian Federation
Victoria V Guzeva
St Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
Email: viktoryka@mail.ru
MD, PhD, Associate Professor, Department of Nervous Diseases Russian Federation
Damir A Malekov
St Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
Email: d.a.malekov@gmail.com
Assistant Professor, Department of Medical Biophysics Russian Federation
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