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Comparative morphofunctional visualization of the manifestations of chronic bacterial and radiation bladder injuries
- Authors: Berdichevskyy B.B.1, Berdichevsky B.A.1, Barashin B.A.1, Keln A.A.1, Naletov A.A.1, Boldyrev A.L.1, Gutrova E.I.1
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Affiliations:
- Tyumen State Medical University of the Ministry of Healthcare of the Russian Federation
- Issue: Vol 11, No 1 (2021)
- Pages: 55-62
- Section: Original study
- Submitted: 26.12.2020
- Accepted: 23.03.2021
- Published: 27.05.2021
- URL: https://journals.eco-vector.com/uroved/article/view/56984
- DOI: https://doi.org/10.17816/uroved56984
- ID: 56984
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Abstract
Comparative morphofunctional and histological visualization of bladder wall lesions in 15 patients with chronic bacterial cystitis and in 15 patients with chronic radiation cystitis using positron emission tomography - computed tomography (PET/CT) was performed. The studies have revealed significant differences in the parameters of blood flow and tissue metabolism in patients with these forms of bladder lesions. In patients with chronic bacterial cystitis, an increase in the frequency of urination was accompanied by a decrease in the capacity of the bladder under conditions of a decrease in the velocity of arterial and venous blood flow in its wall as compared with the control. At the same time, at the cellular-molecular level in the bladder wall, no significant metabolic abnormalities, assessed by the SUVmax indicator, were revealed. Chronic radiation cystitis was characterized by a significant increase in the rate of systolic and diastolic blood flow in the bladder wall, its thickening and hypermetabolism of 18F-FDG.
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About the authors
Berdichevsky B. Berdichevskyy
Tyumen State Medical University of the Ministry of Healthcare of the Russian Federation
Email: urotgmu@mail.ru
ORCID iD: 0000-0002-0186-6514
SPIN-code: 9768-5704
Dr. Sci. (Med), Accosiate of Professor of the Department of Oncology with a course of Urology
Russian Federation, 625023, Tyumen, Odesskaya str., 54Boris A. Berdichevsky
Tyumen State Medical University of the Ministry of Healthcare of the Russian Federation
Author for correspondence.
Email: doktor_bba@mail.ru
ORCID iD: 0000-0002-9414-8510
SPIN-code: 4630-3855
Dr. Sci. (Med), Professor
Russian Federation, 625023, Tyumen, Odesskaya str., 54Barashin A. Barashin
Tyumen State Medical University of the Ministry of Healthcare of the Russian Federation
Email: dmitry_barashin@mail.ru
SPIN-code: 6553-7593
Cand. Sci. (Med), Assistant of the Department of Oncology with a course of Urology
Russian Federation, 625023, Tyumen, Odesskaya str., 54Artem A. Keln
Tyumen State Medical University of the Ministry of Healthcare of the Russian Federation
Email: artyom-keln@ya.ru
SPIN-code: 9633-0276
Cand. Sci. (Med), Assistant of the Department of Oncology with a course of Urology
Russian Federation, 625023, Tyumen, Odesskaya str., 54Anton A. Naletov
Tyumen State Medical University of the Ministry of Healthcare of the Russian Federation
Email: annaletov@mail.ru
SPIN-code: 8946-2000
Assistant of the Department of Oncology with a course of Urology
Russian Federation, 625023, Tyumen, Odesskaya str., 54Aleksej L. Boldyrev
Tyumen State Medical University of the Ministry of Healthcare of the Russian Federation
Email: doktor_bba@mail.ru
Postgraduate, Department of Oncology with a course of Urology
Russian Federation, 625023, Tyumen, Odesskaya str., 54Elena I. Gutrova
Tyumen State Medical University of the Ministry of Healthcare of the Russian Federation
Email: doktor_bba@mail.ru
Postgraduate, Department of Oncology with a course of Urology
Russian Federation, 625023, Tyumen, Odesskaya str., 54References
- Karpin VA. The theoretical scheme of a chronic pathological process. Medical Journal of the Russian Federation. 2006;(2):50–52. (In Russ.)
- Abdullaev NA, Ajdagulova SV, Isaenko VI, Nepomnyashchih LM Kliniko-endoskopicheskie i patomorfologicheskie aspekty differencialnoy diagnostiki hronicheskogo cistita i cistopati. Sibirskij nauchnyj vestnik. 2006;(9):27–31. (In Russ.)
- Pasov VV, Kurpesheva AK. Osnovy luchevoy diagnostiki i terapii: nacionalnoe rukovodstvo. Ed by S.K. Ternovoy Moscow: GEOTAR-Media; 2012. P. 962–990. (In Russ.)
- Ma S, Zhang T, Jiang L, et al. Impact of bladder volume on treatment planning and clinical outcomes of radiotherapy for patients with cervical cancer. Cancer Manag Res. 2019;11:7171–7181. doi: 10.2147/CMAR.S214371
- Franzke CW, Bruckner P, Bruckner-Tuderman L. Collagenous transmembrane proteins: recent insights into biology and pathology. J Biol Chem. 2005;280(6):4005–4008. doi: 10.1074/jbc.R400034200
- Pan Y, Lavelle JP, Bastacky SI, et al. Detection of tumorigenesis in rat bladders with optical coherence tomography. Med Phys. 2001;28(12):2432–2440. doi: 10.1118/1.1418726
- Tararova EA, Krupin VN, Strelcova OS. Dinamika sostoyaniya slizistoy obolochki mochevogo puzyrya v processe luchevogo lecheniya. In: Abstracts of the International Interdisciplinary Symposium “Chronic Pelvic Pain”. 16–17 June 2008. Nizhniy Novgorod. 2008. P. 23–27. (In Russ.)
- Ceradini DJ, Kulkarni AR, Callaghan MJ, et al. Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1. Nat Med. 2004;10(8):858–864. DOI: 10.1038/ nm1075
- Zharinov GM, Vinokurov VL, Zaikin GV Luchevye povrezhdeniya pryamoy kishki I mochevogo puzyrya u bolnyh rakom sheyki matki. Mir Mediciny. 2000;(7–8):12–14. (In Russ.)
- Strelcova OS, Krupin VN, Tararova EA, et al. Mikrocirkulyaciya v “goryachih zonah” mochevogo puzyrya pri luchevom cistite. In: Abstracts of the International Interdisciplinary Symposium “Chronic Pelvic Pain”. 16–17 June 2008. Nizhniy Novgorod. 2008. P. 21–23. (In Russ.)
- Kocherov AA, Kocherova EV Primenenie «Uro-gial» v lechenii stoykoy dizurii u bolnyh s hronicheskim cistitom. Urology reports (St. Petersburg). 2015;5(1):102–104. (In Russ.)
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