Comparative morphofunctional visualization of the manifestations of chronic bacterial and radiation bladder injuries

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Comparative morphofunctional and histological visualization of bladder wall lesions in 15 patients with chronic bacterial cystitis and in 15 patients with chronic radiation cystitis using positron emission tomography - computed tomography (PET/CT) was performed. The studies have revealed significant differences in the parameters of blood flow and tissue metabolism in patients with these forms of bladder lesions. In patients with chronic bacterial cystitis, an increase in the frequency of urination was accompanied by a decrease in the capacity of the bladder under conditions of a decrease in the velocity of arterial and venous blood flow in its wall as compared with the control. At the same time, at the cellular-molecular level in the bladder wall, no significant metabolic abnormalities, assessed by the SUVmax indicator, were revealed. Chronic radiation cystitis was characterized by a significant increase in the rate of systolic and diastolic blood flow in the bladder wall, its thickening and hypermetabolism of 18F-FDG.

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作者简介

Berdichevsky Berdichevskyy

Tyumen State Medical University of the Ministry of Healthcare of the Russian Federation

Email: urotgmu@mail.ru
ORCID iD: 0000-0002-0186-6514
SPIN 代码: 9768-5704

Dr. Sci. (Med), Accosiate of Professor of the Department of Oncology with a course of Urology

俄罗斯联邦, 625023, Tyumen, Odesskaya str., 54

Boris Berdichevsky

Tyumen State Medical University of the Ministry of Healthcare of the Russian Federation

编辑信件的主要联系方式.
Email: doktor_bba@mail.ru
ORCID iD: 0000-0002-9414-8510
SPIN 代码: 4630-3855

Dr. Sci. (Med), Professor

俄罗斯联邦, 625023, Tyumen, Odesskaya str., 54

Barashin Barashin

Tyumen State Medical University of the Ministry of Healthcare of the Russian Federation

Email: dmitry_barashin@mail.ru
SPIN 代码: 6553-7593

Cand. Sci. (Med), Assistant of the Department of Oncology with a course of Urology

俄罗斯联邦, 625023, Tyumen, Odesskaya str., 54

Artem Keln

Tyumen State Medical University of the Ministry of Healthcare of the Russian Federation

Email: artyom-keln@ya.ru
SPIN 代码: 9633-0276

Cand. Sci. (Med), Assistant of the Department of Oncology with a course of Urology

俄罗斯联邦, 625023, Tyumen, Odesskaya str., 54

Anton Naletov

Tyumen State Medical University of the Ministry of Healthcare of the Russian Federation

Email: annaletov@mail.ru
SPIN 代码: 8946-2000

Assistant of the Department of Oncology with a course of Urology

俄罗斯联邦, 625023, Tyumen, Odesskaya str., 54

Aleksej Boldyrev

Tyumen State Medical University of the Ministry of Healthcare of the Russian Federation

Email: doktor_bba@mail.ru

Postgraduate, Department of Oncology with a course of Urology

俄罗斯联邦, 625023, Tyumen, Odesskaya str., 54

Elena Gutrova

Tyumen State Medical University of the Ministry of Healthcare of the Russian Federation

Email: doktor_bba@mail.ru

Postgraduate, Department of Oncology with a course of Urology

俄罗斯联邦, 625023, Tyumen, Odesskaya str., 54

参考

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2. Fig. 1. Functional and morphological visualization of microbial-inflammatory and radiation damage to the bladder: I – uroflowmetry; II – ultrasonography of the bladder with Doppler ultrasonography; III – cystoscopy. a – control group; b – chronic bacterial cystitis; c – chronic radiation cystitis

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3. Fig. 2. Comparative molecular cell and histological imaging of chronic bacterial and chronic and radiation damage to the bladder: I – native positron emission tomography of the upper and lower urinary tract; II – combined positron emission tomography with computed tomography of the bladder; III – histological examination of the bladder wall (stain hematoxylin-eosin). a – control group; b – chronic bacterial cystitis; c – chronic radiation cystitis

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版权所有 © Berdichevskyy B., Berdichevsky B., Barashin B., Colne, A., Naletov А., Boldyrev A., . Gutrova. E., 2021



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