Surgical tactics for Crohn’s disease complicated by intestinal bleeding

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Abstract

BACKGROUND: The course of Crohn’s disease often leads to complications requiring surgical treatment. One of the most serious complications of Crohn’s disease is intestinal bleeding.

AIM: To determine the most optimal timing and extent of surgical treatment in patients with Crohn’s disease complicated by intestinal bleeding when conservative therapy is ineffective.

MATERIALS AND METHODS: The article presents the experience of treating patients with Crohn’s disease complicated by intestinal bleeding at the Center for Gastroenterology and Oncopreventology of the Elizabeth Hospital (Russia) and the Republican Scientific Center of Coloproctology (Uzbekistan).

RESULTS: Despite the possibilities of conservative treatment, in 33% of cases the therapy was ineffective and required urgent surgical intervention. The degree of intervention was selected individually based on multivariate analysis.

CONCLUSIONS: Intestinal bleeding is a life-threatening complication of Crohn’s disease, causing the need for surgical intervention in almost a third of cases. Crohn’s disease is characterized by various damage to the gastrointestinal tract, which require multiple options for resective surgery on the small and large intestines, as well as an individual approach to the degree of intervention. The use of modern methods of complex conservative therapy for Crohn’s disease can reduce the risk of complications and reduce the amount of surgical intervention.

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About the authors

Evgeniy M. Trunin

North-Western State Medical University named after I.I. Mechnikov

Email: Evgeniy.Trunin@szgmu.ru
ORCID iD: 0000-0002-2452-0321
SPIN-code: 5903-0288

MD, Dr. Sci. (Med.), Professor

Russian Federation, Saint Petersburg

Sergey V. Petrov

North-Western State Medical University named after I.I. Mechnikov; City Hospital of the Holy Martyr Elizabeth

Email: petrovsv@eliz-spb.ru
ORCID iD: 0009-0006-5578-3913
SPIN-code: 8151-2024

MD, Dr. Sci. (Med.), Professor

Russian Federation, 41 Kirochnaya St., Saint Petersburg, 191015; Saint Petersburg

Andrey I. Shchegolev

North-Western State Medical University named after I.I. Mechnikov; City Hospital of the Holy Martyr Elizabeth

Email: cionic@yandex.ru
ORCID iD: 0000-0003-1563-2126

MD, Cand. Sci. (Med.)

Russian Federation, 41 Kirochnaya St., Saint Petersburg, 191015; Saint Petersburg

Aleksandr A. Kozobin

North-Western State Medical University named after I.I. Mechnikov; City Hospital of the Holy Martyr Elizabeth

Email: akozobin@mail.ru
ORCID iD: 0000-0003-1527-3848

MD, Cand. Sci. (Med.)

Russian Federation, 41 Kirochnaya St., Saint Petersburg, 191015; Saint Petersburg

Vladislav V. Tatarkin

North-Western State Medical University named after I.I. Mechnikov

Email: Vladislav.Tatarkin@szgmu.ru
ORCID iD: 0000-0002-9599-3935

MD, Cand. Sci. (Med.)

Russian Federation, Saint Petersburg

Anton V. Koshcheev

North-Western State Medical University named after I.I. Mechnikov; City Hospital of the Holy Martyr Elizabeth

Author for correspondence.
Email: kosheev70@yandex.ru
ORCID iD: 0000-0003-1803-5298

MD, Cand. Sci. (Med.)

Russian Federation, 41 Kirochnaya St., Saint Petersburg, 191015; Saint Petersburg

Sayfiddin R. Baymakov

Tashkent State Dental Institute

Email: bsayfiddin@yahoo.com
ORCID iD: 0000-0003-1096-835X

MD, Dr. Sci. (Med.), Professor

Uzbekistan, Tashkent

Sherkabul B. Tagayev

Tashkent State Dental Institute

Email: tagayev.66@mail.ru
ORCID iD: 0009-0004-7661-9253

MD, Dr. Sci. (Med.), Assistant Professor

Uzbekistan, Tashkent

Mirkhokim M. Pulatov

Tashkent State Dental Institute

Email: mir181164@gmail.com
ORCID iD: 0000-0001-6767-7241

MD, Cand. Sci. (Med.), Assistant Professor

Uzbekistan, Tashkent

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  2. Ivashkin VT, Shelygin YuA, Baranskaya YeK, et al. Diagnosis and treatment of the irritable bowel syndrome: clinical guidelines of the Russian gastroenterological association and Russian association of coloproctology. Russian Journal of Gastroenterology, Hepatology, Coloproctology. 2017;27(5):76–93. EDN: ZHQRZJ doi: 10.22416/1382-4376-2017-27-5-76-93
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  7. Goldstone RN, Steinhagen RM. Abdominal emergencies in inflammatory bowel disease. Surg Clin North Am. 2019;99(6):1141–1150. doi: 10.1016/j.suc.2019.08.007
  8. Atroshchenko AO, Kolygin AV, Severova MM, Markushin LI. Crohn’s disease manifested with massive colonic bleeding (review and a clinical case). Koloproktologia. 2021;20(3):84–94. EDN: KCGLQS doi: 10.33878/2073-7556-2021-20-3-84-94

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