Vol 4, No 1 (2014)

Experience of using fluorescence cystoscopy in the diagnosis of superficial bladder cancer. The study involved 103 patients of both sexes (mean age 58,7 ± 6,3 years) who underwent photodynamic diagnosis (PDD) of bladder cancer. For this purpose 5 mg of photoditazine were injected into the bladder dissolved in 20 ml of saline. The exposure time of the drug in the bladder was from 60 to 90 minutes. Then sequentially performed cystoscopy in white and blue light. For fluorescence diagnosis the light flux with a wavelength of 402 nm was used, which corresponded to the maximum peak of photoditazine absorption. The use of PDD revealed bladder cancer in all 103 patients, while in 69 (67 %) patients were identified in a total of 125 plots mucosa, fluorescent in blue light and unaltered in white light. Histological examination of these sites of mucosa in 52 (41.6 %) cases the tumor (transitional cell carcinoma) was morphologically confirmed, in 14 (11.2 %) cases of dysplasia was detected, in 15 (12 %) - squamous metaplasia of the urothelium, in 31 (24.8 %) - inflammatory changes in the urothelium, in 13 (10.4 %) - leukoplakia of the bladder. Thus, the diagnostic sensitivity of the standard cystoscopy in white light was 62.3 %, and PDD with intravesical use of the drug photodithazine - 96.7 %.

The research of the quality of life of 75 patients with diabetic bladder hyperactivity (BH) and 349 patients with idiopathic BH. For the assessment of quality of life the questionnaire KHQ was used. There has been a significant decline in the life quality of the patients of both groups. At the same time the specificies of influence of two forms of BH on some particular aspects of quality of life were marked. When diabetic BH compare to idiopathic BH revealed more severe limitations in daily activities and reducing of emotional status, but less strong influence on personal relationships.

Clinical recommendations concerning pre-hospital emergency health care delivery as well as emergency health care delivery in the clinical department of emergency for the patients with bladder trauma are described. Clinical recommendations were composed based on the modern recommendations of European Association of Urologist. The statistical significance of recommendations is indicated.