Treatment of respiratory tuberculosis in patients with psychiatric disorders

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Abstract

The incidence of mental disorders is increasing, including addiction diseases. HIV infections and tuberculosis are also common in this group of patients. Such combination of diseases creates difficulties for effective tuberculosis treatment and influence on its prevalence. Purpose of the study: to estimate the effectiveness of treatment of respiratory tuberculosis patients with psychiatric disorders, to study the incidence of adverse reactions when using antituberculosis drugs in this group of patients. The study was based on a retrospective cohort study of 390 patients with combined pathology - respiratory tuberculosis and mental disorders. All patients received antituberculosis drugs in a psychiatric hospital. Therapy efficacy depended on the quality of nursing staff, their careful observation of drugs intake and timely registration of adverse reactions (ADRs). An individualized approach to the treatment of TBI in patients with mental disorders, in which the nursing staff actively participates, makes it possible to increase the effectiveness of therapy, timely identify NDAs and stop them.

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About the authors

Olga V. Litvinova

N.V. Postnikov State Clinical Hospital

Author for correspondence.
Email: borodulinbe@yandex.ru

phthisiatrician

Russian Federation, Samara

Elena A. Borodulina

Samara State Medical University Ministry of Health Care of the Russian Federation

Email: borodulinbe@yandex.ru
ORCID iD: 0000-0002-3063-1538

Doctor of Medicine, professor, head of the department of phthisiology and pulmonology

Russian Federation, Samara

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