Trehalose as a special sugar

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Abstract

In recent decades, a significant number of scientific papers have been published devoted to the study of the specific physical and chemical properties of a special sugar – trehalose and its role in living systems. Trehalose is widespread in nature. This unique disaccharide protects proteins and cell membranes from inactivation or denaturation caused by various stress conditions, including desiccation, dehydration, heat, cold, oxidation, heat shock, hypoxia, prolonged absence of oxygen. Trehalose enhances autophagy, protecting cells of organisms from various stress influences; is a powerful modifier of abnormal protein accumulation in human neurodegenerative diseases; has a favorable effect on vascular endothelium; positively affects metabolic processes in the human body, including type 2 diabetes - and this is only a small part of the positive effects that trehalose has on the body.

It is well known that anti-aging medicine is aimed at slowing down aging processes and postponing the manifestation of age-dependent diseases, but so far there are no drugs that can reliably slow down the aging process in humans. Nature has created the molecule trehalose as a unique molecular structure that supports life on our planet and may have given mankind a chance to live longer.

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About the authors

Lydia P. Khoroshinina

St. Petersburg State Pediatric Medical University of the Ministry of Health of the Russian Federation

Author for correspondence.
Email: spb@gpmu.org
ORCID iD: 0000-0002-4930-1424

Doctor of Medical Sciences, Professor, Professor V.A. Waldman Department of Faculty Therapy

Russian Federation, Saint Petersburg

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