Modern ideas about the development of atherosclerosis
- Authors: Askerov E.M.1, Utkina V.A.1, Filich A.S.1, Fisyuk E.A.1
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Affiliations:
- Tver State Medical University of the Ministry of Health of the Russian Federation
- Issue: Vol 26, No 3 (2024)
- Pages: 33-38
- Section: Profession: theory and practice
- URL: https://journals.eco-vector.com/0025-8342/article/view/632429
- DOI: https://doi.org/10.29296/25879979-2024-03-06
- ID: 632429
Cite item
Abstract
Currently, in the leading countries of the world there is a question of a significant increase in diseases associated with circulatory system disorders, but this issue should be considered together with another pathology – atherosclerosis. Analysis of modern scientific literature has shown that at the moment there is no single theory of the origin of atherosclerosis, because this disease can be caused by various factors, both endo- and exogenous. Currently, most scientists and doctors agree that atherosclerosis is a multifactorial disease, in the development of which there are complex, often long-term violations of immunologic, molecular-genetic, biochemical reactions. Many significant structural units are involved in the process of atherogenesis: the vascular wall, local disturbance of blood flow, and blood forming elements. Opinions on the etiology of atherosclerosis vary. However, most authors tend to consider dyslipidemia as the leading mechanism of atherosclerosis development; at the same time, we should not forget other possible causes of its formation.
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About the authors
Elshad M. Askerov
Tver State Medical University of the Ministry of Health of the Russian Federation
Author for correspondence.
Email: elschad.askerov@yandex.ru
ORCID iD: 0000-0002-2567-6088
Candidate of Medical Sciences, Associate Professor of the Department of General Surgery
Russian Federation, TverValeria A. Utkina
Tver State Medical University of the Ministry of Health of the Russian Federation
Email: elschad.askerov@yandex.ru
ORCID iD: 0009-0000-4449-4995
student
Russian Federation, TverAlina S. Filich
Tver State Medical University of the Ministry of Health of the Russian Federation
Email: elschad.askerov@yandex.ru
ORCID iD: 0009-0004-3942-9717
student
Russian Federation, TverEkaterina A. Fisyuk
Tver State Medical University of the Ministry of Health of the Russian Federation
Email: elschad.askerov@yandex.ru
ORCID iD: 0009-0000-0582-7398
student
Russian Federation, TverReferences
- Apresyan A.Yu. Assessment of the prevalence of peripheral artery diseases in the adult population of the Russian Federation. Bulletin of the Ivanovo Medical Academy. 2022; 27 (3): 25–30. doi: 10.52246/1606-8157_2022_27_3_25
- Badeynikova K.K., Mammadov M.N. Early markers of atherosclerosis: predictors of the development of cardiovascular complications. Preventive medicine 2023; 26 (1): 103–108. doi: 10.17116/profmed202326011103
- Kobzeva N.D., Martynov A.I. Modern model of prognostic assessment of the development of fatal cases of myocardial infarction in patients with peripheral. Medical science and education of the Urals. 2022; 23 (3): 138–141. doi: 10.36361/18148999_2022_23_3_138
- Neudakhin E.V., Kozhanova T.V., Zhilina S.S., et al. Genetic risk factors for the development of childhood atherosclerosis. Quantum Satis. 2019; 2 (1): 71–80.
- Morozov A.M., Sergeev A.N., Kadykov V.A. et al. Analysis of public awareness of diseases leading to chronic arterial insufficiency, based on the assessment of the relevance of Google search engine queries. Bulletin of the medical Institute «REAVIZ»: rehabilitation, doctor and health. 2020; 5 (47): 128–137. doi: 10.20340/vmi-rvz.2020.5.15
- Morozov A.M., Sergeev A.N., Askerov E.M. et al. Coronary artery transplantation operations (literature review). Bulletin of the medical institute «REAVIZ»: rehabilitation, doctor and health. 2023; 13 (4): 45–51. doi: 10.20340/vmi-rvz.2023.4.CLEAN.3
- Shurkevich N.P., Vetoshkin A.S., Gapon L.I., Simonyan A.A. Risk factors and subclinical carotid atherosclerosis in rotating scheme conditions in the Arctic.Cardiovascular Therapy and Prevention. 2019; 18 (4): 86–91. doi: 10.15829/1728-8800-2019-4-86-91
- Morozova N.I, Mulerova T.A, Tsygankova D.P. et al. Factors predisposing to the progression of atherosclerosis of the carotid arteries in patients with arterial hypertension. Siberian Medical Review. 2022; (1): 37–44. doi: 10.20333/25000136-2022-1-37-44
- Bubnova M.G. High-intensity lipid-lowering therapy and low-density lipoprotein cholesterol: is this approach justified in clinical practice? A look at the problem. Russian Journal of Cardiology. 2018; (6): 191–200. doi: 10.15829/1560-4071-2018-6-191-200
- Tsygankova D.P., Krivoshapova K.E., Barbarash O.L. Nutrition as a risk factor for cardiovascular pathology in the aspect of epidemiological studies. Cardiovascular therapy and prevention. 2018; 17 (2): 88–94. doi: 10.15829/1728-8800-2018-2-88-94
- Chagina E.A., Turmova E.P., Buraya V.Yu. Pathophysiological risk factors for atherosclerosis. International Journal of Humanities and Natural Sciences. 2022; (3): 11–14. doi: 10.24412/2500-1000-2022-3-3-11-14
- Tseilikman V.E., Lukin A.A. The effect of oxidative stress on the human body. International Research Journal. 2022; 3 (117): 206–211. doi: 10.23670/IRJ.2022.117.3.037
- Kurochkina N.S., Sergienko I.V., Popova A.B. et al. Physiological and pathological role of adipose tissue in atherogenesis. Atherosclerosis and dyslipidemia. 2020; (3): 15–29. DOI: 10.34687f2219-8202.JAD.2020.03.0002
- Bakulin I.S., Tanashyan M.M., Raskurazhev A.A. Endothelial dysfunction and oxidative stress in cerebral atherosclerosis and the possibilities of their pathogenetic correction. Nervous diseases. 2018; (2): 3–10. doi: 10.24411/2226-0757-2018-12016
- Doronin A.A., Pavlina V.A., Sivakova L.V. et al. Etiology and pathogenesis of atherosclerosis. European Journal of Natural History. 2022; (4): 31–35. doi: 10.17513/ejnh.34285
- Susekov A.V. Fenofibrate in the treatment of patients with hypertriglyceridemia and atherosclerosis: new data. Medical business. 2020; (1): 24–37. doi: 10.24411/2071-5315-2020-12189
- Kalinin R.E., Suchkov I.A., Klimentova E.A. et al. Markers of apoptosis, cell proliferation, endothelial dysfunction in atherosclerosis of the arteries of the lower extremities. Bulletin of the National Medical and Surgical Center named after N. I. Pirogov. 2021; 16 (1): 29–32. doi: 10.25881/BPNMSC.2021.26.94.005
- Savitsky D.V., Linkova N.S., Kozhevnikova E.O. et al. SASP of endothelium and vascular smooth muscle cells: role in the pathogenesis and therapy of atherosclerosis. Molecular medicine. 2022; 20 (4): 9–15. doi: 10.29296/24999490-2022-04-02
- Uchasova E.G., Gruzdeva O.V., Dyleva Yu.A. Ceramides and their role in the development of cardiovascular diseases. Clinical laboratory diagnostics. 2020; 65 (6): 341–346. doi: 10.18821/0869-2084-2020-65-6-341-346
- Ilyicheva T.N., Netesov S.V., Abubakirova O.A., Gureev V.N. Respiratory viral infections and their role in human cardiovascular diseases. Siberian Journal of Clinical and Experimental Medicine. 2022; 37 (4): 14–21. doi: 10.29001/2073-8552-2022-37-4-14-21
- Madieva M.I., Abilmazhinova G.D. Modern ideas about the role of infectious agents in the development of cardiovascular diseases. Science and Healthcare. 2020; 3 (22): 42–54. doi: 10.34689/SH.2020.22.3.007
- Klimchuk A.V., Beloglazov V.A., Zalyaeva A.A. Atherosclerosis: immunological aspects of pathogenesis, the role of inflammation, therapeutic strategies, prospects for the use of nanotechnology. Tauride Medico-Biological Bulletin. 2021; 24 (3): 77–89.
- Morozov A.M., Zhukov S.V., Morozova A.D. et al. Modern markers of inflammation. Vrach 2022; 33 (11): 47–52. doi: 10.29296/25877305-2022-11-08
- Morozov A.M., Sergeev A.N., Zhukov S.V. et al. Modern markers of the inflammatory process in surgical practice. Outpatient surgery. 2022; 19 (1): 147–156. doi: 10.21518/1995-1477-2022-19-1-147-156
- Zinoviev P.A., Shubina I.Zh., Yamenskov V.V. et al. Chronic inflammation in the elderly: mechanisms of development and connection with atherosclerosis. Russian Biotherapeutic Journal. 2021; 20 (2): 10–18. doi: 10.17650/1726-9784-2021-20-2-10-18
- Mokhov E.M., Morozov A.M., Kadykov V.A. et al. On the possibility of using C-reactive protein and procalcitonin as relevant and accessible markers of inflammation in surgery. Moscow Surgical Journal. 2018; 2 (60): 24–29. doi: 10.17238/issn 2072-3180.2018.2.24-29
- Kubekina M.V., Nikiforov N.G., Karagodin V.P. et al. Analysis of macrophage transcriptome in atherogenesis. Russian Journal of Cardiology. 2019; (2): 92–98. doi: 10.15829/1560-4071-2019-2-92-98