Anticoagulant therapy after discharge from hospital in patients with COVID-19.
- Authors: Demyanenko А.V.1, Afonaskov О.V.1, Zelenov М.V.1, Pogozhiy Y.S.1
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Affiliations:
- The P.V.Mandryka Central Military Clinical Hospital of the Ministry of Defense of the Russian Federation
- Issue: Vol 345, No 1 (2024)
- Pages: 36-39
- Section: Treatment and prophylactic issues
- URL: https://journals.eco-vector.com/0026-9050/article/view/627327
- DOI: https://doi.org/10.52424/00269050_2024_345_1_36
- ID: 627327
Cite item
Abstract
The feasibility of prescribing anticoagulants and the role of prolonged anticoagulant therapy in the period after discharge from hospital currently remain incompletely studied. From December 2020 to December 2021, dynamic monitoring of patients who had COVID-19 was carried out. The number of confirmed cases of pulmonary embolism, deep and superficial vein thrombosis, and major bleeding within 30 days after discharge was determined. There were 2 cases of pulmonary embolism, 4 cases of deep vein thrombosis of the leg according to color duplex scanning, 6 cases (1.04%). There was no bleeding. The prescription of direct oral anticoagulants in prophylactic doses after COVID-19 is justified if indicated.
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About the authors
А. V. Demyanenko
The P.V.Mandryka Central Military Clinical Hospital of the Ministry of Defense of the Russian Federation
Author for correspondence.
Email: theicemann99@gmail.com
заслуженный врач РФ, кандидат медицинских наук, полковник медицинской службы
Russian Federation, MoscowО. V. Afonaskov
The P.V.Mandryka Central Military Clinical Hospital of the Ministry of Defense of the Russian Federation
Email: theicemann99@gmail.com
доктор медицинских наук, полковник медицинской службы
Russian Federation, MoscowМ. V. Zelenov
The P.V.Mandryka Central Military Clinical Hospital of the Ministry of Defense of the Russian Federation
Email: theicemann99@gmail.com
кандидат медицинских наук, подполковник медицинской службы
Russian Federation, MoscowYu. S. Pogozhiy
The P.V.Mandryka Central Military Clinical Hospital of the Ministry of Defense of the Russian Federation
Email: theicemann99@gmail.com
капитан медицинской службы
Russian Federation, MoscowReferences
- Временные методические рекомендации по лечению новой коронавирусной инфекции. Версия 15.
- Есипов А.В., Алехнович А.В., Абушинов В.В. COVID-19: Первый опыт оказания медицинской помощи и возможные решения проблемных вопросов (Обзор) // Госпит. медиц.: наука и практика. – 2020. – № 1. – С. 5–9.
- Зайцев А.А., Савушкина О.И., Черняк А.В., Кулагина И.Ц., Крюков Е.В. Клинико-функциональная характеристика пациентов, перенесших новую коронавирусную инфекцию COVID-19 // Практич. пульмонол. – 2020. – № 1. – С. 78–81.
- Зайцев А.А., Чернов С.А., Стец В.В., Паценко М.Б., Кудряшов О.И., Чернецов В.А., Крюков Е.В. Алгоритмы ведения пациентов с новой коронавирусной инфекцией COVID-19 в стационаре: Метод. реком. // Consilium Medicum. – 2020. – Т. 22, № 11. – С. 91–97.
- Крайнюков П.Е., Демьяненко А.В., Афонасков О.В., Гудантов Р.Б., Попов А.В., Диева Т.В. Опыт лечения тяжелой формы коронавирусной инфекции COVID-19 в центральном военном госпитале // Воен.-мед. журн. – 2020. – Т. 341, № 10. – С. 63–66.
- Крайнюков П.Е., Демьяненко А.В., Машков Т.Н., Абашин В.Г. Клиническое течение новой коронавирусной инфекции у лиц диспансерной группы // Воен.-мед. журн. – 2021. – Т. 342, № 10. – С. 31–36.
- Крюков Е.В., Тришкин Д.В., Салухов В.В., Ивченко Е.В. Опыт военной медицины в борьбе с новой коронавирусной инфекцией // Вестн. Рос. акад. наук. – 2022. – Т. 92, № 7. – С. 699–706. doi: 10.31857/S086958732207009X
- Тришкин Д.В., Крюков Е.В., Чернецов В.А., Чернов С.А. Лечение пациентов с тяжелой коронавирусной инфекцией // Воен.-мед. журн. – 2021. – Т. 342, № 2. – С. 66–68.
- Courtney L.A., Toby C.T. Evaluation of the Clinical Impact of Thromboprophylaxis in Patients With COVID-19 Following Hospital Discharge // The Annals of Pharmacotherapy. – 2022. – Vol. 56, N 9. – P. 981–987.
- Dobesh P.P., Trujillo T.C. Coagulopathy, Venous Thromboembolism, and Anticoagulation in Patients with COVID-19 // Pharmacotherapy. – 2020. – Vol. 40, N 11. – P. 1130–1151.
- Giannis D., Allen S.L. Postdischarge thromboembolic outcomes and mortality of hospitalized patients with COVID-19: the CORE-19 registry // Blood. – 2021. – Vol. 137, N 20. – P. 2838–2847.
- Granger C.B., Alexander J.H. Apixaban versus warfarin in patients with atrial fibrillation // N. Engl. J. of Medicine. – 2011. – Vol. 365, N 11. – P. 981–992.
- Iturbe-Hernandez T., Garcнa de Guadiana Romualdo L. Dabigatran, the oral anticoagulant of choice at discharge in patients with non-valvular atrial fibrillation and COVID-19 infection: the ANIBAL protocol // Drugs in Context. – 2020. – Vol. 9. – P. 2020.
- Jimйnez D., Garcнa-Sanchez А. Incidence of VTE and Bleeding Among Hospitalized Patients With Coronavirus Disease 2019: A Systematic Review and Meta-analysis // Chest. – 2021. – Vol. 159. – P. 1182–1196.
- Moores L.K., Tritschler T. Thromboprophylaxis in Patients With COVID-19: A Brief Update to the CHEST Guideline and Expert Panel Report // CHEST. – 2022. – Vol. 162, N 1. – P. 213–225.
- Patell R., Bogue T. Postdischarge thrombosis and hemorrhage in patients with COVID-19 // Blood. – 2020. – Vol. 136, N 11. – P. 1342–1346.
- Ramacciotti E., Leandro B.A. Rivaroxaban versus no anticoagulation for post-discharge thromboprophylaxis after hospitalisation for COVID-19 (MICHELLE): an open-label, multicentre, randomised, controlled trial // Lancet (London, England). – 2022. – Vol. 399, N 10319. – P. 50–59.
- Roberts L.N., Whyte M.B. Postdischarge venous thromboembolism following hospital admission with COVID-19 // Blood. – 2020. – Vol. 136, N 11. – P. 1347–1350.
- Schulman S., Kearon C. Definition of major bleeding in clinical investigations of antihemostatic medicinal products in non-surgical patients // J. of Thrombosis and Haemostasis. – 2005. – Vol. 3. – P. 692–694.
- Singhania N., Bansal S. Current Overview on Hypercoagulability in COVID-19 // Am. J. of Cardiovascular Drugs: Drugs, Devices and Other Interventions. – 2020. – Vol. 20, N 5. – P. 393–403.
- Spyropoulos A.C. Extended post-discharge thromboprophylaxis in hospitalized COVID-19 patients // Expert Rev. of Hematology. – 2022. – Vol. 15, N 7. – P. 597–605.
- Spyropoulos A.C., Levy J.H. Scientific and Standardization Committee communication: Clinical guidance on the diagnosis, prevention, and treatment of venous thromboembolism in hospitalized patients with COVID-19 // J. of Thrombosis and Haemostasis. – 2020. – Vol. 18, N 8. – P. 1859–1865.
- Spyropoulos A.C., Lipardi C. Modified IMPROVE VTE Risk Score and Elevated D-Dimer Identify a High Venous Thromboembolism Risk in Acutely Ill Medical Population for Extended Thromboprophylaxis // TH Open: Companion J. to Thrombosis and Haemostasis. – 2020. – Vol. 4, N 1. – P. e59–e65.