Features of blood transfusions in the period of traumatic shock in patients with severe concomitant injury with acute massive blood loss of severe and extremely severe stage

Acute massive blood loss remains the leading cause of death in the first hours of traumatic disease in more than 50% of deceased patients. In this regard, in the case of acute massive and extremely severe blood loss and delayed evacuation of the wounded, it is advisable to study the efficacy and safety of transfusions of red blood-containing blood products of the universal donor (0 (I) Rh-), starting with the first level of care (first aid, first medical). It has been established that involuntary use of red blood cells containing blood products of a universal donor in the first hours after injury in victims with acute massive severe blood loss is as effective as the use of phenotyped red blood cells containing drugs authentic in group and rhesus affiliation and is not accompanied by the development of blood transfusion reactions. In addition, early (in the first 6 hours) and complete replenishment of acute massive blood loss of an extremely severe degree compared with double replenishment of such blood loss (within 24 hours) is accompanied by a more stable course of traumatic disease, reduces the required volume of blood transfusions in the first 3 days (on average 0.96± 0.11 l), and does not entail an increase in the frequency and severity of the massive hemotransfusion syndrome.

severe concomitant injury, acute massive blood loss, blood transfusion