Vol 26, No 3 (2015)

The paper considers occupational lesions of the cardiovascular system upon exposure to harmful physical and chemical factors of production, as well as diseases caused by functional overexertion.

The paper gives the results of an investigation assessing arterial rigidity, clinical status, and prog-nosis in the active and standard management of patients with prior myocardial infarction and symptoms of chronic heart failure.

The high prevalence and social significance of diseases associated with Helicobacter pylori (Нр), its increased antibiotic resistance, and the lower efficiency of eradication therapy necessitate a search for ways to enhance therapeutic efficiency. One of them is adjuvant probiotic intake that contributes to a reduction in antibiotic-associated adverse reactions and increases adherence to treatment. Lactobacillus reuteri DSMZ 17648 is noted to form specific coaggregates with Hp, and to decrease gastric bacterization, which may promote the higher efficiency of eradication therapy. The possibility of monotherapy with a L. reuteri DSMZ 17648 agent in Hp-infected persons who have no strict indications for eradication is being investigated.

The paper considers the pathogenesis of dyspeptic symptoms in patients who have undergone cholecystectomy, and, among other issues, specifies the role of small intestinal bacterial overgrowth. It is shown that Zacofalc may be the drug of choice in the combination therapy of patients with cholelithiasis after cholecystectomy. This therapy is aimed at relieving dyspeptic symptoms, the pathogenesis of which involves the impaired small and large intestinal microflora that occupies a prominent place.

Anomalous origin of the right coronary artery from the pulmonary trunk concurrent with aortopulmonary septal defect is an extremely rare abnormality. The paper describes a clinical case of this abnormality in a 2-month-old infant who underwent one-stage radical surgery for the defect: plasty of aortopulmonary septal defect with a xenopericardial flap; creation of an intrapulmonary tunnel with a xenopericardial flap (Takeuchi procedure); ligation of the patent ductus arteriosus; suture of the patent fenestra vestibuli under extracorporeal circulation and hypothermia.

Sixty-seven patients with nonrheumatic myocarditis (NRM) were examined to evaluate the efficiency of a cycle of combination therapy with Galavit. Thirty-two patients received Galavit (5 intramuscular injections and 10 suppositories for one month according the scheme) in addition to basic therapy. The use of Galavit in the combination therapy in patients with NRM was ascertained to promote elimination of myocardial inflammatory processes, improvement of intracardiac hemodynamic parameters, and stabilization of the general clinical status and immunological parameters.

The paper describes the efficacy of Thiotriazoline used in the combination antiinflammatory therapy of acute salpingoophoritis in correcting the most important components of its pathogenesis - lipid peroxidation and antioxidant defense system. There is convincing evidence that Thiotriazoline has a positive effect on these homeostatic parameters in the patients; it is concluded that it is justifiable to use the drug regardless of the site of an inflammatory process.

The paper gives the current definition, classification, pathogenesis of dysmenorrhea in adolescent girls, and principles of its treatment and discusses the efficiency of the latter with nonsteroidal anti-inflammatory drugs.

The paper assesses the results of surgical treatment in 25 patients operated on by X-ray surgical procedures for ulceronecrotic changes in the distal lower extremities in the presence of severe arterial ischemia. The minimal risk of infectious complications and the possibility of performing surgery in severely somatically ill patients are the major benefits of angioplasty and stenting in the presence of a purulent focus in the foot. An immediate postoperative positive result as resolved critical ischemia and a preserved foot could be obtained in 21 (84%) patients. In the late postoperative period of 6 months to 3 years, the results were traced in 19 (76%) patients; the limb preservation rate was 73.7%.

Left ventricular noncompaction (LVNC) is rare form of genetically heterogeneous primary cardiomyopathy. The diagnosis, clinical manifestations, and treatment of LVNC are discussed.

A questionnaire survey was conducted to assess the awareness of the physicians of therapeutic-and-prophylactic institutions about coronary heart disease patients’ referrals for sociomedical examination after coronary bypass surgery.