Vol 28, No 4 (2017)

In the presented review of literature examined the morphological changes and dysfunction of mitochondria, especially in cardiomyocytes, due to the cardiotoxic side effect of antipsychotics. Special attention is paid to the pathogenesis of mitochondrial dysfunction, as well as one of its main manifestations of oxidative stress.

Diabetes mellitus (DM) retains its value as one of the most important cardiovascular risk factors in both the general population and patients with verified cardiovascular diseases. Moreover, the assessment of an individual risk for cardiovascular events in DM is a subject of scientific debate. The possibility of stratifying patients with DM into groups at risk for poor prognosis, by using biological markers, is considered.

The paper presents the results of osteoarthritis treatment based on the Plasmolifting™ technology (a stimulation technique for tissue regeneration using autologous platelet-rich plasma).

The given observation will contribute to an improvement in the early diagnosis of the manifestations of extrapulmonary tuberculosis in patients with HIV infection and disseminated pulmonary tuberculosis. The arising difficulties are related to the peculiarities of the course of tuberculosis in the presence of immunosuppressive diseases.

The paper gives data from investigations of Coenzyme Q10 used to treat cardiovascular diseases in adults and children, as well as the results of clinical trials of this drug that has shown its efficacy and safety.

The authors investigated the impact of simulating the intraoperative casing position by the Bernoulli techniques (to set up the casing in the horizontal position) on the duration of surgery and the stone-free state during minipercutaneous nephrolithotomy.

The authors retrospectively analyzed the functional results of 40 sphincter-sparing resections and quality of life indicators during 71 operations for rectal cancer (40 patients underwent intersphincteric resection (ISR) and 31 extralevator abdominoperineal extirpations (EAPE); the distal edge of the tumor from the anal verge was <5 cm). The functional results (the quality of anal continence) met the patients’ expectations in 89.8% of cases; the signs of low anterior resection syndrome were recorded in 94% of the cases. The quality of life indicators did not significantly differ in patients undergoing ISR and EAPE (p=0.046).

The diagnostic capabilities of diffusion-weighted magnetic resonance imaging versus multislice spiral computed tomography in the staging of ovarian cancer are estimated.

The paper gives data on the mechanisms of action of homeopathic remedies. The authors present their own results of using complex homeopathic medicines in emergency situations without a prior or subsequent cycle of treatment

Due to the fact that there is no classification of bone defects in primary knee arthroplasty, the Anderson Orthopedic Research Institute (AORI) classification (for revision arthroplasty) is used most commonly. The authors propose a classification to describe bone defects in primary arthroplasty on the affected side, the area and depth of involvement in the pathological process.

Research is made according to the algorithms of the program of World Health Organization «MONICA - psychosocial» on the representative population sample in Tyumen among men in an amount of 850 people. The analysis of this study showed that in men aged 25-64 years Tyumen was unfavorable epidemiological situation on the prevalence of coronary heart disease. The highest readiness to implement prevention programs among the urban population of the city of Tyumen found in groups of individuals with already identified pathology that reduces the likelihood of the potential effectiveness of these programs in the General population. In General, the presented data demonstrate a high need in the prevention of coronary heart disease in people of working age, who demonstrated in groups of men aged 25-64 years with and without coronary heart disease.