Vol 28, No 10 (2017)

Current possibilities of thoracic anesthesiology, intensive-care medicine, and surgical technologies allow simultaneous operations with immediate and long-term results comparable to those after staging surgery.

Diverticular disease of the colon is often asymptomatic, its marked clinical manifestations occur only during the development of complications, such as inflammation, abscess, or perforation. The symptoms of the disease are varied and nonspecific, which requires that more sophisticated diagnostic methods be developed. According to the magnitude of clinical manifestations and the severity of patients’ status, medical or surgical treatment for this disease can be both outpatient and inpatient. The current methods for the diagnosis and treatment of diverticular disease and its complications are reviewed.

Urethrooculosynovial syndrome is a systemic disease with the incompletely understood etiology and mechanisms of development. Early eradication of trigger infection and adequate anti-inflammatory and immunomodulatory therapy may achieve a complete cure.

Chronic pulmonary infection is a consequence of impaired mucociliary clearance in cystic fibrosis (CF). Patients with CF receive long-term cycles of high-dose antibacterial therapy (ABT). A study of the causes of antibiotic resistance and adverse reactions (ARs) is promising in these patients. The impact of polymorphic variants in the CYP3A4 gene on the risk of ARs during ABT and on the predisposition to gram-negative infection was investigated in children with CF.

Mirizzi syndrome (MS) is a rare, severe complication of cholelithiasis, the original morphological sign of which is the compression of the proximal part of the hepaticocholedochus, which culminates in the formation of either a stricture or a cholecystobiliary fistula. For the preliminary diagnosis of MS, it is necessary to remember its basic and additional criteria (clinical, instrumental, including ultrasonographic and laboratory). The preoperative diagnosis of MS is a very difficult task for surgeons and ultrasonic diagnosticians; its solution makes it possible to choose adequate diagnostic and treatment tactics and to avoid complications during surgery for complicated calculous cholecystitis.

Применение токолитической терапии позволило уменьшить количество осложнений у новорожденных, родившихся в сроки до 33 нед гестации.

The paper presents the combined use of botulinum toxin type A and the antidepressant venlafaxine in patients with chronic migraine. The findings indicate the efficacy and safety of the proposed therapeutic strategy that has simultaneously an impact on different pathophysiological mechanisms of migraine as a primary disease and on comorbidities and modifiable factors for chronicity of headache, the most important of which are depression and excessive use of analgesics.

The paper shows the features of treatment in children with speech disorders due to hypoxic and ischemic lesions in the central nervous system. It presents data on the combined use of glycine, logopedic massage, and artificial local hypothermia.

The use of flupirtine in chronic low back pain contributed to less pain intensity with a significant decrease in the levels of anxiety and depression and with better quality of life in patients.

The paper compares the efficiency of visual diagnostic techniques in patients with drug-induced osteonecrosis and aseptic osteomyelitis of the jaw bone.

Exostosis is a nontumor bony outgrowth that is usually located on the surface of the intact bone. The paper describes a rare clinical case of multiple recurrent existoses in maxillary sinus in the presence of chronic purulent and productive hemisinusitis.

The paper gives data on the diagnostic value of cartilage oligomeric matrix protein in connective tissue disease. The authors briefly outline the results of their own investigation aimed at determining the level of this protein as a biomarker of cartilage metabolism in children with hip dysplasia.