Application of continuous amnioinfusion via a subcutaneous port system for premature rupture of membranes and at less than 28 weeks of gestation. The first experience in Russia


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Abstract

Premature rupture of membranes (PROM) is one of the major causes of high neonatal mortality and morbidity. Very preterm PROM, fetal pulmonary hypoplasia, and fetal inflammatory response syndrome are associated with the loss of amniotic fluid and the development of oligo/anhydramnios. Objective. To extend the duration of pregnancy prolongation without increasing the infection risk with continuous amnioinfusion via a subcutaneous port system. Materials and methods. A patient with PROM at 25 weeks’ gestation had continuous amnioinfusion (100 ml/h, 2400 ml/day, SDP (4±2 cm)) via a subcutaneous port, by using a hypotonic solution by the properties similar to those of amniotic fluid. Conclusion. The f irst experience with continuous amnioinfusion allowed us to increase the interval of pregnancy prolongation up to 10 days in PROM. This new method can certainly be used in pregnant women with PROM and oligo/anhydramnios at term < 28/0 weeks of gestation.

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About the authors

Vitaly B. Tskhai

Krasnoyarsk State Medical University named after V.F. Voyno-Yasenetsky

Email: tchai@yandex.ru
MD., prof., Head of Department of Perinatology, Obstetrics and Gynecology, Medical Faculty

Yury I. Naberezhnev

Voronezh State University; Voronezh State University

Email: rubick@yandex.ru
M.D., senior researcher, Department of Genetics, Cytology and Bioengineering

Michael N. Chirikov

University Hospital Halle (Saale), Martin Luther University Halle-Wittenberg; Voronezh State University

Prof. MD, PhD, Director of Department of Obstetrics and Prenatal Medicine, Center of Fetal Surgery

Tatjana T. Lobanova

Krasnoyarsk Regional Clinical Center of Maternity and Childhood

Email: oufd_pc@pericentr.ru
Head of Department of Ultrasound and Functional diagnostics

Anna Yu. Dudina

V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; Krasnoyarsk Regional Clinical Center of Maternity and Childhood

Email: anybar@mail.ru
assistant of Department of Perinatology, Obstetrics and Gynecology, Medical Faculty; Obstetrician-gynecologist of Department of Pregnancy Pathology Unit №1.

Oleg V. Golovchenko

Belgorod National Research University

Email: capit68@mail.ru
M.D., Associate Professor, Department of Obstetrics and Gynecology Medical Faculty

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