Biomorphological features and antioxidant activity of mint species of non-hybrid origin growing in the North Caucasus region

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Abstract

Introduction. Modern researchers note the role of antioxidants in the correction of fat and carbohydrate metabolism, so the search for new raw materials for obtaining substances with antioxidant activity is relevant. Polyphenolic compounds are considered the most powerful natural antioxidants. Our attention was drawn to non-hybrid mint species growing in the North Caucasus region.

Objective. Study of biomorphological features and economically valuable characteristics of the species Mentha L. (Lamiaceae), their phytochemical characteristics based on the content of essential oil and some phenolic compounds, determination of antioxidant activity to substantiate the prospects for use in medicine and pharmacy.

Material and methods. The studies were carried out according to the methods of the State Pharmacopoeia (SP) XIV and XV editions. Samples of raw mint (M. arvensis L.), watermint (M. aquatica L.), longleaf mint (M. longifolia (L.) Huds.), flea mint (M. pulegium L.), m spicata (M. spicata L.), harvested in forest-steppe and steppe zones, as well as on mountain slopes, damp places, sometimes in wastelands, in North Ossetia – Alania, Karachay-Cherkessia, Kabardino-Balkaria and the Stavropol Territory in their natural places of growth (end of July–August 2021–2023). Objects were dried using the air-shadow method. Antioxidant activity was determined by amperometric and titrimetric methods.

Results. Non-hybrid mint species growing in the North Caucasus contain essential oils, hydroxycinnamic and triterpene acids, flavonoids and polyphenolic compounds. The established antioxidant properties of hydroalcoholic extracts of mint species, in addition to the traditionally known choleretic and antispasmodic effects, can be considered significant for reducing body weight.

Conclusion. The content of essential oil and polyphenolic compounds in various types of mint, as well as the established antioxidant properties of aqueous-alcoholic extracts, in addition to the traditionally known choleretic and antispasmodic effects, can be considered significant for weight loss.

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About the authors

Ivan V. Popov

Pyatigorsk Medical and Pharmaceutical Institute, branch of the Volgograd State Medical University

Author for correspondence.
Email: beegeeslover@mail.ru
ORCID iD: 0009-0002-1163-057X

Candidate of pharmaceutical sciences, associate professor of the department of pharmacognosy, botany and technology of herbal medicines

Russian Federation, Kalinin Avenue, 11, Pyatigorsk, 357532

Stella G. Yakovleva

Pyatigorsk Medical and Pharmaceutical Institute, branch of the Volgograd State Medical University

Email: ystella@mail.ru
ORCID iD: 0000-0002-8911-720X

Candidate of pharmaceutical sciences, associate professor of the department of pharmacognosy, botany and technology of herbal medicines

Russian Federation, Kalinin Avenue, 11, Pyatigorsk, 357532

Olga I. Popova

Pyatigorsk Medical and Pharmaceutical Institute, branch of the Volgograd State Medical University

Email: beegeeslover@mail.ru
ORCID iD: 0009-0004-8235-073X

Doctor of pharmaceutical sciences, professor, professor of the department of pharmacognosy, botany and technology of herbal medicines

Russian Federation, Kalinin Avenue, 11, Pyatigorsk, 357532

Irina A. Samylina

FSAEI of HE I.M.Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)

Email: samylina_i_a@staff.sechenov.ru
ORCID iD: 0000-0002-4895-0203

Doctor of Pharmaceutical Sciences, corresponding member of the RAS, Professor, professor of the Pharmaceutical Natural Sciences Department at Institute of Pharmacy named after A.P. Nelyubin

Russian Federation, Trubetskaya str., 8/2, Mosсow, 119991

Elena V. Kovtun

Pyatigorsk Medical and Pharmaceutical Institute, branch of the Volgograd State Medical University

Email: elena.f.73@mail.ru
ORCID iD: 0000-0003-3437-760X

Сandidate of Pharmaceutical Sciences, аssociate Professor of the Department of Pharmaceutical Technology with a course in Medical Biotechnology

Russian Federation, Kalinin Avenue, 11, Pyatigorsk, 357532

Dmitry O. Bokov

FSAEI of HE I.M.Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University); Federal Research Center of Nutrition and Biotechnology

Email: bokov_d_o@staff.sechenov.ru
ORCID iD: 0000-0003-2968-2466

Сandidate of Pharmaceutical Sciences, associate professor, associate professor of the Pharmaceutical Natural Sciences Department at Institute of Pharmacy named after A.P. Nelyubin; researcher of laboratory of chemistry of food products

Russian Federation, Trubetskaya str., 8/2, Mosсow, 119991; Ustinsky proezd, build. 2/14, Moscow, 109240

Tatyana Y. Tatarenko-Kozmina

Moscow State Medical and Dental University named after A.I. Evdokimov

Email: kosmtina025@gmail.com
ORCID iD: 0009-0000-8569-9209

Doctor of Biological Sciences, Professor, Head of Department of Medical Biology with the Fundamentals of Cellular and Molecular Biotechnology of the Scientific Research Institute “Clinical Medicine named after Semashko"

Russian Federation, st. Delegatskaya, 20, build. 1, Moscow, 127473

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