Medicinal herbal preparations and herbal medicines for complex therapy and rehabilitation of COPD in elderly patients
- Authors: Chevidaev V.V.1, Rodin M.N.1, Bokov D.O.1,2, Bessonov V.V.2,3, Samylina I.A.1
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Affiliations:
- Sechenov First Moscow State Medical University (Sechenov University)
- Scientific Institution “Federal Research Center of Nutrition and Biotechnology”
- Peoples' Friendship University of Russia (RUDN University)
- Issue: Vol 74, No 1 (2025)
- Pages: 13-21
- Section: Pharmaceutical chemistry and pharmacognosy
- URL: https://journals.eco-vector.com/0367-3014/article/view/656655
- DOI: https://doi.org/10.29296/25419218-2025-01-02
- ID: 656655
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Abstract
Introduction. Chronic obstructive pulmonary disease (COPD) ranks high in mortality worldwide. In addition to preventive recommendations, the implementation of which allows the patient to reduce or eliminate the influence of certain risk factors that cause or aggravate COPD, there are also pharmacotherapeutic approaches. Thus, as part of complex pharmacotherapy and rehabilitation of COPD in elderly patients, medicinal plant raw materials (MPRMs), which are part of medicinal herbal preparations (MHP) or herbal medicines (HM), can be used as mucoactive components. This article provides information on trade names, international nonproprietary names (INN), release forms and manufacturers of drugs of the plant origin expectorants pharamacotherapeutic group on the Russian pharmaceutical market.
The purpose of the work is to analyze the nomenclature of medicinal herbal preparations and medicinal plant products registered in the territory of the Russian Federation and used in the complex therapy of COPD in elderly patients.
Material and methods. Information and analytical search for names of herbal medicines and herbal medicines in specialized databases.
Results. Analysis of the nomenclature of herbal medicines and herbal medicines revealed 63 trade names. Among them, the most common herbal medicines are licorice roots, common thyme herb, marshmallow roots, creeping thyme herb, vascular adathoda leaves, common ivy leaves, large plantain leaves, long pepper fruits, medicinal ginger rhizomes and spring primrose roots. The main groups of biologically active compounds (BACs) in the most common herbal medicines are polysaccharides, essential oils, saponins, flavonoids, alkaloids.
Conclusion. The number of trade names, the number of single-component and multicomponent herbal medicines and herbal medicines were determined. The most common herbal medicines in the composition of these drugs were established. The prevailing dosage forms were identified. Information on groups of BACs prevailing on the Russian pharmaceutical market of medicinal plant raw materials is reflected.
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About the authors
Vladimir Viktorovich Chevidaev
Sechenov First Moscow State Medical University (Sechenov University)
Author for correspondence.
Email: chevidaev_v_v@staff.sechenov.ru
ORCID iD: 0000-0003-4696-9960
assistant in pharmaceutical sciences of the Pharmaceutical Natural Sciences Department
Russian Federation, st. Trubetskaya, 8, bldg. 2, Moscow, 119991Mikhail Nikolaevich Rodin
Sechenov First Moscow State Medical University (Sechenov University)
Email: rodin_m_n@staff.sechenov.ru
ORCID iD: 0000-0001-9532-6879
PhD student of the Pharmaceutical Natural Sciences Department
Russian Federation, st. Trubetskaya, 8, bldg. 2, Moscow, 119991Dmitry Olegovich Bokov
Sechenov First Moscow State Medical University (Sechenov University); Scientific Institution “Federal Research Center of Nutrition and Biotechnology”
Email: bokov_d_o@staff.sechenov.ru
ORCID iD: 0000-0003-2968-2466
PhD in Pharmaceutical Sciences, Associate Professor of the Pharmaceutical Natural Sciences Department at Institute of Pharmacy named after A.P. Nelyubin, Sechenov First Moscow State Medical University (Sechenov University); Researcher of laboratory of chemistry of food products at the Federal State Budgetary Scientific Institution “Federal Research Center of Nutrition and Biotechnology”
Russian Federation, st. Trubetskaya, 8, bldg. 2, Moscow, 119991; Ustinsky proezd, building 2/14, Moscow, 109240Vladimir Vladimirovich Bessonov
Scientific Institution “Federal Research Center of Nutrition and Biotechnology”; Peoples' Friendship University of Russia (RUDN University)
Email: bessonov@ion.ru
ORCID iD: 0000-0002-3587-5347
Doctor of Biological Sciences, Head of the Laboratory of Food Chemistry, laboratory of chemistry of food products at the Federal State Budgetary Scientific Institution “Federal Research Center of Nutrition and Biotechnology”; Professor of the Department of Ecology and Food Safety, Peoples' Friendship University of Russia (RUDN University)
Russian Federation, Ustinsky proezd, building 2/14, Moscow, 109240; Miklukho-Maklaya St., 6, Moscow, 117198Irina Alexandrovna Samylina
Sechenov First Moscow State Medical University (Sechenov University)
Email: samylina_i_a@staff.sechenov.ru
ORCID iD: 0000-0002-4895-0203
Doctor of Pharmaceutical Sciences, corresponding member of the RAS, professor of the Pharmaceutical Natural Sciences Department
Russian Federation, st. Trubetskaya, 8, bldg. 2, Moscow, 119991References
- World Health Organization. Chronic obstructive pulmonary disease (COPD). Accessed: March 16, 2023.
- Lamprecht B., McBurney M.A., Vollmer W.M., Gudmundsson G., Welte T., Nizankowska-Mogilnikka E., Studnicka M., Bateman E., Anto J., Berni P., Mannino D.M., Buist S.A., BOLD Collaborative Research Group. COPD in never smokers: results form the population-based burden of obstructive lung disease study. Chest. 2011; 139: 752–63. doi: 10.1378/chest.10-1253.
- Mehta A.J., Miedinger D., Keidel D., Betschart R., Bircher A., Bridevo P-O, Kururik I., Kromhout H., Rocha T., Rothe T., Russi E.V., Schikowski T., Schindler S., Schwarz J., Türk A., Vermeulen R., Probst-Hensch N., Künzli N., SAPALDIA team. Occupational exposure to dusts, gases, and fumes and incidence of chronic obstructive pulmonary disease in the Swiss Cohort Study on Air Pollution and Lung and Heart Diseases in Adults. Am. J. Respir Crit Care Med. 2012; 185: 1292–300. doi: 10.1164/rccm.201110-1917OC.
- Eisner M.D., Antonisen N., Coultas D., Kuenzli N., Perez-Padilla R., Postma D., Romier I., Silverman E.K., Balmes J.R., COPD Committee for Nonsmokers, Assembly on Environmental and Occupational Health. An official American Thoracic Society public policy statement: novel risk factors and the global burden of chronic obstructive pulmonary disease. Am. J. Respir Crit Care Med. 2010; 182: 693–718. doi: 10.1164/rccm.200811-1757ST.
- Чичкова Н.В. Растительные препараты в комплексной терапии заболеваний органов дыхания. Фарматека. 2017; 14: 46–51. [Chichkova N.V. Plant-based preparations in the complex therapy of respiratory diseases. Farmateka. 2017; 14: 46–51 (in Russian)]
- Государственная фармакопея Российской Федерации XV издания. Доступ: https://pharmacopoeia.regmed.ru/pharmacopoeia/izdanie-15/ [State Pharmacopoeia of the Russian Federation, XV edition. Retrieved from https: //pharmacopoeia.regmed.ru/pharmacopoeia/izdanie-15/ (in Russian)]
- Mamedov N.A., Egamberdieva D. Phytochemical constituents and pharmacological effects of licorice: a review. Plant and Human Health, Volume 3: Pharmacology and Therapeutic Applications. 2019; 1–21. doi: 10.1007/978-3-030-04408-4_1.
- Patil S.M., Ramu R., Shirahatti P.S., Shivamallu K., Amachavadi R.G. A systematic review on ethnopharmacology, phytochemistry and pharmacological aspects of Thymus vulgaris Linn. Helion. 2021; 7 (5). doi: 10.1016/j.heliyon.2021.e07054.
- Al-Snafi A.E. The pharmaceutical importance of Althaea officinalis and Althaea rosea: A review. Int J. Pharm Tech Res. 2013; 5 (3): 1387–5.
- Carneiro M.R.B., Salloum L.O., Martins H.L.R., Peixoto J.D.C., Napolitano H.B., Rosseto L.P. Overview of the Justicia genus: insights into its chemical diversity and biological potential. Molecules. 2023; 28 (3): 1190. doi: 10.3390/molecules28031190.
- Salaria D., Rolta R., Lal U.R., Dev K., Kumar V. A comprehensive review on traditional applications, phytochemistry, pharmacology, and toxicology of Thymus serpyllum. Indian J. of Pharmacology. 2023; 55 (6): 385–94. doi: 10.4103/ijp.ijp_220_22.
- Shokry A., El-Sheikh R., Kamel G., Ramadan A. Phytochemical contents, biological activities and therapeutic applications of Hedera helix (ivy leaf) extracts: a review. The Natural Products J. 2022; 12 (4): 22–32. doi: 10.2174/2210315511666210917111801.
- Adom M.B., Taher M., Mutalabisin M.F., Amri M.S., Qudos M.B.M., Sulaiman Wang M.W.A., Sengupta P., Susanti D. et al. Chemical constituents and medical benefits of Plantago major. Biomedicine and pharmacotherapy. 2017; 96: 348–60. doi: 10.1016/j.biopha.2017.09.152.
- Khushbu K., Roshni S., Anar P., Carol M., Mayuri P. Phytochemical and therapeutic potential of Piper longum Linn a review. International J. of Research in Ayurveda and Pharmacy. 2011; 2 (1): 157–61.
- Быков И.И., Компанцев Д.В., Привалов И.М. Экстрагирование биологически активных веществ из Zingiber officinalе Roscoe в технологии фитопрепаратов (обзор). Вестник Смоленской государственной медицинской академии. 2017; 2. [Bykov I.I., Kompantsev D.V., Privalov I.M. Extraction of biologically active substances from Zingiber officinale Roscoe in herbal remedies technology (review). Vestnik Smolenskoi gosudarstvennoi meditsinskoi akademii. 2017; 2 (in Russian)].
- Müller A., Gansera M., Stuppner H. Analysis of phenolic glycosides and saponins in Primula elatior and Primula veris (primula root) by liquid chromatography, evaporative light scattering detection and mass spectrometry. J. of Chromatography A. 2006; 1112 (1–2): 218–23. doi: 10.1016/j.chroma.2005.10.067.
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