Antihistamines of the 2nd and 3rd generation in Russia
- Authors: Krylova O.V.1, Mamontova E.R.2, Marchenko S.D.1, Radushnova M.V.1, Paskar N.G.1
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Affiliations:
- Sechenov First Moscow State Medical University
- Pirogov Russian National Research Medical University
- Issue: Vol 74, No 3 (2025)
- Pages: 62-68
- Section: Organization and economy
- URL: https://journals.eco-vector.com/0367-3014/article/view/680121
- DOI: https://doi.org/10.29296/25419218-2025-03-09
- ID: 680121
Cite item
Abstract
Introduction. Antihistamines play an important role in the treatment of allergic diseases, which are becoming more common in metropolitan areas. Currently, more and more patients are turning to specialists with symptoms of allergic rhinitis. According to the clinical guidelines for the treatment of allergic rhinitis, approved in 2024 and revised no later than 2026, all patients with allergic rhinitis are recommended to prescribe systemic antihistamines without sedation in order to reduce itching in the nasal cavity, sneezing, rhinorrhea, and nasal congestion:
- Desloratadine (ATC code: R06AX27);
- Levocetirizine (ATC code: R06AE09);
- Loratadine** (ATC code: R06AX13);
- Cetirizine** (ATC code: R06AE07);
The purpose of this study is to compare antihistamine drugs (drugs) of different generations according to the following criteria: the range of prescriptions according to ICD-10, adverse reactions during use, the range of these drugs; to study the trend of demand and seasonality.
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About the authors
Olga Valerievna Krylova
Sechenov First Moscow State Medical University
Email: krylova_o_v@staff.sechenov.ru
ORCID iD: 0000-0002-0552-639X
Associate Professor at the Department of Pharmacy of the Nelyubin Institute of Pharmacy
Russian Federation, MoscowElsa Ruslanovna Mamontova
Pirogov Russian National Research Medical University
Email: elza.mamontova@mail.ru
ORCID iD: 0000-0001-8199-2053
Associate Professor at the Department of Pharmacy of the Institute of Pharmacy and Medicinal Chemistry
Russian Federation, MoscowSevara Dzhurabekovna Marchenko
Sechenov First Moscow State Medical University
Email: marchenko_s_d@staff.sechenov.ru
ORCID iD: 0000-0002-0177-6826
Associate Professor at the Department of Organization and Management in the Field of Drug Circulation of the Institute of Professional Education
Russian Federation, MoscowMaria Vladislavovna Radushnova
Sechenov First Moscow State Medical University
Email: masharadushnova@list.ru
ORCID iD: 0009-0004-3722-6756
5th-Year Student at the Nelyubin Institute of Pharmacy
Russian Federation, MoscowNikita Grigorievich Paskar
Sechenov First Moscow State Medical University
Author for correspondence.
Email: nnikpaskar@yandex.ru
ORCID iD: 0009-0002-6656-6667
5th-Year Student at the Nelyubin Institute of Pharmacy
Russian Federation, MoscowReferences
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