Evaluation of the effectiveness of herbal medicine in the complex treatment of urolithiasis

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Abstract

Introduction. Based on research of scientific data, to conduct a comprehensive review and comparative characteristics of the effectiveness of the use of herbal medicines for the treatment of urolithiasis.

Aim. Study of scientific works on the analysis of their influence on stones and clinical outcomes at the stages of preparation for remote lithotripsy and in the postoperative period, as well as comparison of their therapeutic activity with the use of only antispasmodics or lithotripsy without additional pharmacotherapy.

Methods. The following information resources were used to search for relevant studies: electronic databases PubMed, Google Scholar, elibrary, CyberLeninka and Cochrane Library. The following key queries were used in the work: “urolithiasis”, “phytotherapy”, “rowatinex”, “canephron”, “urolesan”, “phytolysin”, “cystone”. The search depth was 33 years (1992–2025). A total of 2330 publications were found, after excluding duplicates, invalid works, publications with no free access to the full text, the final number of works included in this literature review in the direction of “herbal medicine” and “urolithiasis” was 16. The total number of sources in the article is 34.

Results. The conducted analysis of scientific literature allowed to establish that medicinal herbal preparations demonstrate significant efficiency in the treatment of urolithiasis. Combined use of herbal preparations with remote lithotripsy showed advantages in decreasing the frequency of complications, decreasing the size of stones, facilitating their passage and decreasing the need for repeated procedures. The review confirms the advisability of including herbal medicine in complex treatment regimens for urolithiasis.

Conclusion. Analysis of literary data confirmed the effectiveness of herbal medicines in the treatment of urolithiasis, in combination with lithotripsy.

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About the authors

Yulia Vitalievna Shikova

Federal State Budgetary Educational Institution of Higher Education “Bashkir State Medical University”, Ministry of Health of the Russian Federation

Author for correspondence.
Email: shikmann@mail.ru
ORCID iD: 0000-0001-7593-2839

Doctor of Pharmaceutical Sciences, Professor, Head of the Department of Pharmaceutical Technology and Biotechnology

Russian Federation, st. Lenina, 3, Ufa, 450008, Republic of Bashkortostan

Victoria Vitalievna Petrova

Federal State Budgetary Educational Institution of Higher Education “Bashkir State Medical University”, Ministry of Health of the Russian Federation

Email: petrovaviki@yandex.ru
ORCID iD: 0009-0004-6948-8005

Candidate of Pharmaceutical Sciences, Associate Professor, Department of pharmaceutical technology and biotechnology

Russian Federation, st. Lenina, 3, Ufa, 450008, Republic of Bashkortostan

Ekaterina Ilyinichna Ziva

Federal State Budgetary Educational Institution of Higher Education “Bashkir State Medical University”, Ministry of Health of the Russian Federation

Email: katya.ziva@gmail.com
ORCID iD: 0009-0000-4213-3838

Assistant of the Department of Pharmaceutical Technology and Biotechnology

Russian Federation, st. Lenina, 3, Ufa, 450008, Republic of Bashkortostan

Vladimir Khamitovich Bikbulatov

Federal State Budgetary Educational Institution of Higher Education “Bashkir State Medical University”, Ministry of Health of the Russian Federation

Email: cent71@mail.ru
ORCID iD: 0009-0007-4397-6790

assistant of the department of pharmaceutical technology and biotechnology

Russian Federation, st. Lenina, 3, Ufa, 450008, Republic of Bashkortostan

Aleksey Vitalievich Likhoded

City Center of Dentistry LLC

Email: Shikmann555@gmail.com
ORCID iD: 0009-0008-2346-1922

Candidate of Medical Sciences, Dentist-Therapist

Russian Federation, st. 50-letiya Oktyabrya, 2, prem. 2, Ufa, 450005, Republic of Bashkortostan

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2. Fig. 1. Effect of Rovatinex on the passage of stones [17]

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3. Fig. 2. Effect of Urolesan on the size of stones [23]

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4. Fig. 3. Effect of Urolesan on the density of stones [23]

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5. Fig. 4. The effect of Phytolysin on the passage of stones and general urine analysis [34]

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