Trace element status of plant for standardizing of herb raw material
- 作者: Kruglov D.S.1, Prokuscheva D.L.1, Velichko V.V.1
-
隶属关系:
- Novosibirsk State Medical University
- 期: 卷 72, 编号 6 (2023)
- 页面: 12-18
- 栏目: Pharmaceutical chemistry and pharmacognosy
- URL: https://journals.eco-vector.com/0367-3014/article/view/624327
- DOI: https://doi.org/10.29296/25419218-2023-06-02
- ID: 624327
如何引用文章
详细
Introduction. Standardizing herb raw material which guarantees the reproducibility of the quality of phytomedicines is important procedure for plants sources having multicomponent composition of biologically active compounds. The trace element composition plants is determined primarily by the species of the plant like as biological compound composition. The formed cluster of high-quality herb raw material should differ significantly from the non-quality one.
Objective: Assess the possibility of using clusters of trace element statuses for standardization of phytomedicine «Thymi serpyllii herba».
Material and methods. The above-ground shoots of Thymus vulgaris L., Th. serpyllum L., Th. marschallianus Willd., Th. iljinii Klokov & Des.-Shost., and Ziziphora clinopodioides Lam. In addition, the objects of the study were: a phytomedicine from pharmacy assortment «Thymi serpyllii herba» (as a reference drug) and created mixtures of thyme and ziziphora as samples that did not meet the requirements of the standard. The content of trace elements was determined by mass spectroscopy with inductively coupled plasma.
Results. It was established samples of wild thyme and pharmacy phytomedicine which was taken as a standard, form one cluster that is different from the others. At the same time, raw materials Th. serpyllum with an adulterant of Ziziphora clinopodioides fall into clusters different from the cluster of quality samples of Th. serpyllum.
Conclusion. As a result of the work carried out, it was established that the trace element composition of plants allows, using the method of cluster analysis, to form a certain reference cluster.
全文:
![受限制的访问](https://journals.eco-vector.com/lib/pkp/templates/images/icons/text_lock.png)
作者简介
Dmitriy Kruglov
Novosibirsk State Medical University
编辑信件的主要联系方式.
Email: kruglov_ds@mail.ru
ORCID iD: 0000-0002-6027-5730
PhD in Technical Sciences, Associate Professor, Associate Professor at the Department of Pharmacognosy and Botany of Novosibirsk State Medical University
俄罗斯联邦, Krasny prospect, 52, Novosibirsk, 630091Daria Prokuscheva
Novosibirsk State Medical University
Email: mak_dl@mail.ru
ORCID iD: 0009-0009-0480-2311
PhD in Pharmaceutical Sciences, Associate Professor, Associate Professor at the Department of Pharmacognosy and Botany of Novosibirsk State Medical University
俄罗斯联邦, Krasny prospect, 52, Novosibirsk, 630091Viktoriya Velichko
Novosibirsk State Medical University
Email: velichkvik@rambler.ru
ORCID iD: 0000-0002-9224-9350
PhD in Pharmaceutical Sciences, Associate Professor, Head of Department of Pharmacognosy and Botany of Novosibirsk State Medical University
俄罗斯联邦, Krasny prospect, 52, Novosibirsk, 630091参考
- Kruglov D.S., Ovchinnikova S.V. Trace element composition of the family Boraginaceae plant. Rastitel'nyj mir Aziatskoj Rossii. 2013; 1 (9): 77–95 (in Russian)
- Kruglov D.S., Prokuscheva D.L. Trace element composition of the most weidespread of the genus Artemisia L. plants. Khimija Rastitel’nogo Syr’ja. 2022; 3: 139–49. DOI: 10.14258 (in Russian)
- Tikhonov L.A. An overview of capabilities for cluster analysis of data found in the statistica advanced software package. Polytechnichnij molodezhnij zhurnal. 2018; 01: 1–10. doi: 10.18698/2541-8009-2018-01-230 (in Russian)
- Knyazev M.S. Review of Species of the Genus Thymus (Lamiaceae) in Eastern Europe and the Urals. Botanicheskij zhurnal. 2015; 2: 4–141. doi: 10.1134/S0006813615020027 (in Russian)
- Agili F.A. Chemical Composition, Antioxidant and Antitumor Activity of Thymus vulgaris L. Essential Oil. Middle-East Journal of Scientific Research. 2014; 21 (10): 1670–6. doi: 10.5829/idosi.mejsr.2014.21.10.85182
- Durnova N.A., Romanteeva Y.V., Kovtun A.N. The chemical composition of the essential oil of Thymus marshallianus Willd. and Thymus pallasianus H. BR., growing in the Saratov region. Khimija Rastitel’nogo Syr’ja. 2014; 2: 115–9. doi: 10.14258/jcprm.1402115 (in Russian)
- Sefidkon F., Dabiri M., Mirmostafa S. A. The Composition of Thymus serpyllum L. Oil. Journal of Essential Oil Research. 2011; 16 (3): 184–5. doi.Org/10.1080/10412905.2004.9698691
- Tkachev A.V., Prokuscheva D.L., Domrachev D.V. Wild essential oil plants of Southern Siberia. Novosibirsk: “Ofset-Tm”, 2017; 575 (in Russian)
- Sadgrove N.J., Padilla-Gonzalez G.F., Phumthum M. Fundamental Chemistry of Essential Oils and Volatile Organic Compounds, Methods of Analysis and Authentication. Plants. 2022; 11 (6): 2–34 https://doi.org/10.3390/plants11060789
补充文件
![](/img/style/loading.gif)