Email this article Chronic exposure to ultrasonic frequencies results in selective increase of aggression level in rats
- Authors: Gorlova A.V.1, Pavlov D.P.1,2, Ushakova V.M.1, Zubkov E.A.3, Morozova A.Y.3, Zorkina Y.A.3, Inozemtsev A.N.1, Chekhonin V.P.3
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Affiliations:
- Lomonosov Moscow State University
- Institute Of General Pathology And Pathophysiology
- Serbsky National Medical Research Centre of Psychiatry and Narcology under the RF Ministry of Public Health
- Issue: Vol 486, No 6 (2019)
- Pages: 753-755
- Section: Physiology
- URL: https://journals.eco-vector.com/0869-5652/article/view/14520
- DOI: https://doi.org/10.31857/S0869-56524866753-755
- ID: 14520
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Abstract
We studied aggression in male Sprague-Dawley rats in a model of a depressive-like state induced by unpredictable treatment with ultrasonic waves with the frequencies of 20-45 kHz for 1, 2 or 3 weeks. We did not find any increase in the number of animals exhibiting aggression in the “Resident- intruder” test after the treatment of any chosen duration. However, the aggressive animals exposed to ultrasound exhibited increased number of attacks and their total duration as well as decreased latency of the first attack compared to the respective scores in the animals of the control group. Taking this into account, we suggest that the initial level of aggression increases in a model of ultrasonic chronic stress.
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About the authors
A. V. Gorlova
Lomonosov Moscow State University
Author for correspondence.
Email: anna.gorlova204@gmail.com
Russian Federation, 1, Leninskie gory, Moscow, 119991
D. P. Pavlov
Lomonosov Moscow State University; Institute Of General Pathology And Pathophysiology
Email: anna.gorlova204@gmail.com
Russian Federation, 1, Leninskie gory, Moscow, 119991; 8, Baltiyskaya st., Moscow, 125315
V. M. Ushakova
Lomonosov Moscow State University
Email: anna.gorlova204@gmail.com
Russian Federation, 1, Leninskie gory, Moscow, 119991
E. A. Zubkov
Serbsky National Medical Research Centre of Psychiatry and Narcology under the RF Ministry of Public Health
Email: anna.gorlova204@gmail.com
Russian Federation, 23, Kropotkin lane, Moscow, 119034
A. Y. Morozova
Serbsky National Medical Research Centre of Psychiatry and Narcology under the RF Ministry of Public Health
Email: anna.gorlova204@gmail.com
Russian Federation, 23, Kropotkin lane, Moscow, 119034
Y. A. Zorkina
Serbsky National Medical Research Centre of Psychiatry and Narcology under the RF Ministry of Public Health
Email: anna.gorlova204@gmail.com
Russian Federation, 23, Kropotkin lane, Moscow, 119034
A. N. Inozemtsev
Lomonosov Moscow State University
Email: anna.gorlova204@gmail.com
Russian Federation, 1, Leninskie gory, Moscow, 119991
V. P. Chekhonin
Serbsky National Medical Research Centre of Psychiatry and Narcology under the RF Ministry of Public Health
Email: anna.gorlova204@gmail.com
Academician of the Russian Academy of Sciences Russian Federation, 23, Kropotkin lane, Moscow, 119034
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