Mineral-polymer composites based on hydroxyapatite with polyvynylpyrrolidon for medicine

Cover Page

Abstract


Composites of hydroxyapatite (HA) with polyvinylpyrrolidone (PVP) were synthesized by precipitation in water solutions, mass relations of HA/PVP varied in region 3,6-14,5. The composite materials were investigated using XRD, IR, electron paramagnetic resonance (EPR) spectroscopy and transmission electron microscopy (TEM). Based on the TEM results it was found that during calcination of composites at 400 °C small agglomerates consisting of individual crystalline HA particles were formed, resulting in a particle size (according to TEM) slightly larger than coherent scattering region. Using the method of photoinduced EPR spectroscopy confirmed the presence of interaction between HA and PVP. The resulting composites can be used as materials for reconstructive surgery.


About the authors

I. V. Fadeeva

Baikov Institute of Metallurgy and Materials Science of the Russian Academy of Sciences

Author for correspondence.
Email: fadeeva_inna@mail.ru

Russian Federation, 49, Leninskii Prospect, Moscow, 119334

F. I. Grabovenko

Lomonosov Moscow State University

Email: fadeeva_inna@mail.ru

Russian Federation, 1, Leninskie gory, Moscow, 119991

A. S. Fomin

Baikov Institute of Metallurgy and Materials Science of the Russian Academy of Sciences

Email: fadeeva_inna@mail.ru

Russian Federation, 49, Leninskii Prospect, Moscow, 119334

S. M. Barinov

Baikov Institute of Metallurgy and Materials Science of the Russian Academy of Sciences

Email: fadeeva_inna@mail.ru

Russian Federation, 49, Leninskii Prospect, Moscow, 119334

Corresponding Member of the Russian Academy of Sciences

F. F. Murzakhanov

Kazan Federal University

Email: fadeeva_inna@mail.ru

Russian Federation, 18, Kremliovskaya street, Kazan, 420008

A. I. Ahmed

Kazan Federal University

Email: fadeeva_inna@mail.ru

Russian Federation, 18, Kremliovskaya street, Kazan, 420008

G. V. Mamin

Kazan Federal University

Email: fadeeva_inna@mail.ru

Russian Federation, 18, Kremliovskaya street, Kazan, 420008

References

  1. Vallet-Regi M. Ceramics for Medical Applications // J. Chem. Soc. Dalton Trans. 2001. № 2. С. 97-108.
  2. Баринов С. М. Керамические и композиционные материалы на основе фосфатов кальция для медицины // Успехи химии. 2010. Т. 79. № 1. С. 15-32.
  3. Zhang Y., Lu J. A Mild and Efficient Biomimetic Synthesis of Rodlike Hydroxyapatite Particles with a High Aspect Ratio Using Polyvinylpyrrolidone as Capping Agent // Crystal Growth and Design. 2008. V. 8. № 7. P. 2101-2107.
  4. Schöller K., Ethirajan A., Zeller A., Landfester K. Biomimetic Route to Calcium Phosphate Coated Polymeric Nanoparticles: Influence of Different Functional Groups and pH // Macromol. Chem. and Phys. 2011. V. 212. P. 1165-1175.
  5. Langroudi M.M., Saravani M. G., Nouri A. Surfactant-Assisted Synthesis of Polyvinylpyrrolidone-Hydroxyapatite Composites as a Bone Filler // J. Appl. Biomaterials & Funct. Materials. 2017. V. 15. № 4. P. 334-340.
  6. Сидельковская Ф. П. Химия N винилпирролидона и его полимеров. М.: Наука, 1970. 155 с.
  7. Ronfard H.J.C., Lablache C. A., Chachaty C. Electron Spin Resonance of Gamma Irradiation Induced Free Radicals in Polyvinylpyridines // J. Phys. Chem. 1974. V. 78. № 9. P. 899-907.
  8. Пшежецкий С.Я., Котов А. Г., Милинчук В. К. и др. ЭПР свободных радикалов в радиационной химии. М.: Химия, 1972. 480 с.
  9. Радциг В. А. Механохимия полимеров глазами метода ЭПР (обзор) // Хим. физика. 2004. Т. 23. № 10. С. 70-109.
  10. Gabbasov B., Gafurov M., Starshova A., Shurtakova D., Murzakhanov F., Mamin G., Orlinskii S. Conventional, Pulsed and High-Field Electron Paramagnetic Resonance for Studying Metal Impurities in Calcium Phosphates of Biogenic and Synthetic Origins // J. Magnetism and Magnetic Materials. 2019. V. 470. P. 109-117.
  11. Gafurov M., Biktagirov T., Mamin G., Orlinskii S. A DFT, X and W Band EPR and ENDOR Study of Nitrogen-Centered Species in (Nano) Hydroxyapatite // Appl. Magnetic Resonance. 2014. V. 45. № 11. P. 1189-1203.

Statistics

Views

Abstract - 260

PDF (Russian) - 190

PlumX


Copyright (c) 2019 Russian academy of sciences

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies