Email this article Kinetics of chemical processes in the human brain. Modeling of the BOLD-signal at f-MRT research
- Authors: Varfolomeev S.D.1,2, Semenova N.A.1, Bykov V.I.1, Tsybenova S.B.1
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Affiliations:
- Institute of Biochemical Physics of the Russian Academy of Sciences
- Lomonosov Moscow State University
- Issue: Vol 488, No 2 (2019)
- Pages: 157-161
- Section: Physical chemistry
- URL: https://journals.eco-vector.com/0869-5652/article/view/16067
- DOI: https://doi.org/10.31857/S0869-56524882157-161
- ID: 16067
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Abstract
A kinetic model describing the impulse of increasing oxygen in the excited nervous tissue of the human brain in response to an external signal is presented. The model is based on biochemical data and describes experimental data on an impulsed hemodynamic response. The model predicts the dynamic behavior of the process participants, which preceding the oxygen impulse and determining the level of the BOLD-signal.
About the authors
S. D. Varfolomeev
Institute of Biochemical Physics of the Russian Academy of Sciences; Lomonosov Moscow State University
Email: vibykov@mail.ru
Corresponding Member of the Russian Academy of Sciences
Russian Federation, 4, Kosygina street, Moscow, 119991; 1, Leninskie gory, Moscow, 119991N. A. Semenova
Institute of Biochemical Physics of the Russian Academy of Sciences
Email: vibykov@mail.ru
Russian Federation, 4, Kosygina street, Moscow, 119991
V. I. Bykov
Institute of Biochemical Physics of the Russian Academy of Sciences
Author for correspondence.
Email: vibykov@mail.ru
Russian Federation, 4, Kosygina street, Moscow, 119991
S. B. Tsybenova
Institute of Biochemical Physics of the Russian Academy of Sciences
Email: vibykov@mail.ru
Russian Federation, 4, Kosygina street, Moscow, 119991
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