Email this article Copper-containing nanosystems based on macromolecular hydrophilic stabilizers
- Authors: Valueva S.V.1, Nazarova O.V.1, Vylegzhanina M.E.1, Borovikova L.N.1, Zolotova Y.I.1, Panarin E.F.1,2
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Affiliations:
- Institute of Macromolecular Compounds of the Russian Academy of Sciences
- Peter the Great St.Petersburg Polytechnic University
- Issue: Vol 489, No 3 (2019)
- Pages: 254-257
- Section: Chemistry
- URL: https://journals.eco-vector.com/0869-5652/article/view/18582
- DOI: https://doi.org/10.31857/S0869-56524893254-257
- ID: 18582
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Abstract
An original method for the synthesis of copper-containing nanosystems for biomedical applications using hydrazine hydrate as a reducing agent, intermediate stage of formation of complex ion [Cu(NH3)4]2+, which allows to obtain Cu0 nanoparticles without impurities of oxides has been developed. As a macromolecular hydrophilic stabilizer copolymer of 2-deoxy‑2-methacrylamido-D‑glucose with 2-dimethylaminoethylmethaacrylate or bovine serum albumin were used. It has been shown that such stabilization allows to achieve almost unimodal distribution of copper nanoparticles in aqueous solutions due to their rather good shielding by macromolecules.
About the authors
S. V. Valueva
Institute of Macromolecular Compounds of the Russian Academy of Sciences
Author for correspondence.
Email: svalu67@mail.ru
Russian Federation, 31, Bolshoy prospect, St-Petersburg 199004
O. V. Nazarova
Institute of Macromolecular Compounds of the Russian Academy of Sciences
Email: svalu67@mail.ru
Russian Federation, 31, Bolshoy prospect, St-Petersburg 199004
M. E. Vylegzhanina
Institute of Macromolecular Compounds of the Russian Academy of Sciences
Email: svalu67@mail.ru
Russian Federation, 31, Bolshoy prospect, St-Petersburg 199004
L. N. Borovikova
Institute of Macromolecular Compounds of the Russian Academy of Sciences
Email: svalu67@mail.ru
Russian Federation, 31, Bolshoy prospect, St-Petersburg 199004
Yu. I. Zolotova
Institute of Macromolecular Compounds of the Russian Academy of Sciences
Email: svalu67@mail.ru
Russian Federation, 31, Bolshoy prospect, St-Petersburg 199004
E. F. Panarin
Institute of Macromolecular Compounds of the Russian Academy of Sciences; Peter the Great St.Petersburg Polytechnic University
Email: svalu67@mail.ru
Corresponding Member of the Russian Academy of Sciences
Russian Federation, 31, Bolshoy prospect, St-Petersburg 199004; 29, Polytechnitcheskaya street, St.-Petersburg, 195251References
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