Rational Choice of Treatment for Initial Stages of Gonarthrosis in Patients with Systemic Osteoporosis



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Abstract

Results of open controlled study of 60 outpatients aged 45-70 years, with systemic osteoporosis (postmenopausal and idiopathic) and I-II stages of gonarthrosis by Kellgren - Lawrence classification are presented. All patients were divided into 2 groups: study group (n=30) and control group (n=30). Additional treatment for gonarthrosis (Artra drug for 3 months) was prescribed only to patients from the study group. It was shown that study drug decreased significantly (p<0.001) pain intensity by VAS that was accompanied by either marked elimination or disappearance of synovitis by US study results. On the contrary, patients from control group showed trustworthy increase of pain intensity (p=0.015) by that term. Improvement of condition in study group was achieved in 90.4% of patients by physician’s assessment and in 95.5% by patients’ assessment. On the contrary, in control group aggravation of condition was observed in 75.0% and 84.8% of patients, respectively.

About the authors

S. S Rodionova

Central Institute of Traumatology and Orthopaedics named after N.N. Priorov, Moscow, Russia

Email: rod06@inbox.ru

N. A Es’kin

Central Institute of Traumatology and Orthopaedics named after N.N. Priorov, Moscow, Russia

N. Yu Matveeva

Central Institute of Traumatology and Orthopaedics named after N.N. Priorov, Moscow, Russia

N. S Morozova

Central Institute of Traumatology and Orthopaedics named after N.N. Priorov, Moscow, Russia

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