The aim of this study was the evaluation of the neuropathic component influence on the pain intensity, formation of anxiety, depression and pain catastrophization in patients with RA. It was found that the presence of neuropathic pain in RA was associated with higher indexes of depression, anxiety, pain catastrophization level. Furthermore, neuropathic pain in RA led to more frequent occurrence of personal anxiety in more severe form and increased the pain catastrophization level. It turned out to be the aggravating influence of neuropathic pain on the level of psychological comfort and the formation of maladaptive pain settings in RA patients.

About the authors

Elena V Muslimova

Kazan State Medical University

Department of Hospital Therapy with the course of Endocrinology 420012, Каzan, Butlerov str., 49

Svetlana P Yakupova

Kazan State Medical University

Department of Hospital Therapy with the course of Endocrinology 420012, Каzan, Butlerov str., 49

Eduard Z Yakupov

Kazan State Medical University

Department of Neurology, Neurosurgery and Medical Genetics 420012, Каzan, Butlerov str., 49

Tatyana G Sakovets

Kazan State Medical University

Department of Neurology and Rehabilitation 420012, Каzan, Butlerov str., 49


  1. Ахунова Р.Р. Cоматопсихические взаимоотношения при ревматоидном артрите: Дис. … канд. мед. наук. Оренбург: Оренб. гос. мед. академия, 2012. C. 20.
  2. Данилов А.Б., Данилов Ал.Б. Биопсихосо-циокультурная модель и хроническая боль // Боль. 2013. № 1. C. 30-36.
  3. Девликамова Ф.И., Cафина Д.Р. Факторы, cпособствующие длительному сохранению нейропатической боли при травмах периферических нервов // Практическая медицина. 2012. № 2. Режим доступа: boli-pri-travmax-perifericheskix-nervov/
  4. Зелтынь А.Е., Фофанова Ю.C., Лисицына Т.А. и др. Хронический стресс и депрессия у больных ревматоидным артритом // Социальная и клиническая психиатрия. 2009. №2. C. 69-76.
  5. Cаковец Т.Г. Особенности нейропатической боли при поражении суставов // Практическая медицина. 2014. T.1, № 4 (80). C. 105.
  6. Филатова Е.C. Алексеев В.В., Эрдес Ш.Ф. Болевой синдром при ревматоидном артрите // Научно-практическая ревматология. 2011. № 6. C. 32-35.
  7. Чичасова Н.В. Лечение невоспалительной боли в практике ревматолога // Современная ревматология. 2013. № 2. C. 24.
  8. Adebajo A., Fabule J. Management of radicular pain in rheumatic disease: insight for the physician // Ther. Adv. Musculoscel. Dis. 2012. № 4(3). P. 141.
  9. Covic T., Adamson B., Spencer D. et al. A biopsychosocial model of pain and depression in rheumatoid arthritis: a 12-month longitudinal study // Rheumatology (Oxford). 2003. № 42 (11). P. 1287-1294.
  10. Frank R.G. Beck N.C., Parker J.C. et al. Depression in rheumatoid arthritis // J. Rheumatol. 1988. № 15. P. 920-944.
  11. Gautreau C.M., Sherry S.B., Sherry D.L. et al. Does Catastrophizing of Bodily Sensations Maintain Health-Related Anxiety? A 14-Day Daily Diary Study with Longitudinal Follow-Up // Behav. Cogn. Psychother. 2014. May Vol. 1. P. 1-11. [Epub ahead of print].
  12. Jensen M.P. Turner J.A., Romano J.M. Changes in beliefs, catastrophising and coping are associated with improvement in multidisciplinary pain treatment // J. Consult Clin. Psychol. 2001. № 69. P. 655-662.
  13. Mankovsky T., Lynch M., Clark A. et al. Pain catastrophizing predicts poor response to topical analgesics in patients with neuropathic pain // Pain Res Manage. 2012. №17 (1). P. 10-14.
  14. Perrot S., Dieude P., Perocheoue D. et al. Comparison of pain, pain burden, coping strategies and attitudes between patients with systemic sclerosis and patients with rheumatoid arthritis: a cross-sectional study // PainMed. 2013. № 14 (11). P. 1776-1785.
  15. Sullivan M.J.L. Theoretical perspectives on the relation between catastrophizing and pain // Clin. J. Pain. 2001. №17. P. 52-64.
  16. Sullivan M.J.L., Bishop S., Pivic J. The Pain Catastrophizing Scale: Development and Validation // Psychological Assessment. 1995. № 7 ( 4). P. 524-532.
  17. Turk D.C., Monarch E.S. Biopsychosocial perspective on chronic pain. In: Psychological Approaches to Pain Management: A Practitioner’s Handbook, 2nd edition. New York: Guilford, 2002.
  18. Yalcin I. Barthas F., Barrot M. Emotional consequences of neuropathic pain: Insight from preclinical studies // Neurosci. Biobehav. Rev. 2014. P. 154-164. [Epub ahead of print].



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