Study of the functioning of mirror neurons in normal conditions, in neurological and psychiatric diseases: a systematic review of the literature

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Abstract

The mirror neuron system is a fundamental brain system of the brain that provides the ability to understand the actions of others and plays a key role in motor learning and empathy. In this review, we have thoroughly examined the internal and external factors that influence the functioning of the mirror neuron system. Issues such as difficulties in interpreting the mu rhythm and its relationship to theory of mind, which are particularly salient when analysing the mirror neuron system in the context of mental illness, have been identified. The role of the mirror neuron system in the formation of various mental disorders and neurological diseases has been considered. Additionally, a promising direction for future research is highlighted — the study of the mirror neuron system in the context of Parkinson's disease, focusing on the peculiarities of the functioning of the dopaminergic system of the mirror neuron system under normal conditions and in the presence of pathology. Prospective directions for further research are suggested, including the analysis of the mu-rhythm, the role of mentalization, studying the mirror neuron system in mental and neurological diseases.

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About the authors

Aynur A. Ragimova

Center for Cognition and Decision Making, Institute for Cognitive Neuroscience, HSE University; Research Center of Neurology

Email: ragimovaasia@gmail.com
ORCID iD: 0000-0002-4370-4249
SPIN-code: 8489-7627

MD, Cand. Sci. (Med.), Researcher, psychiatrist, psychotherapist

Russian Federation, Moscow; Moscow

Gleb S. Perevoznyuk

Center for Cognition and Decision Making, Institute for Cognitive Neuroscience, HSE University

Email: gotlibb@gmail.com
ORCID iD: 0000-0002-7521-2767
SPIN-code: 3777-9849

MD, Life Sciences Master

Russian Federation, Moscow

Beatrice A. Volel

First Moscow State Medical University named after I.M. Sechenov

Email: beatrice.volel@gmail.com
ORCID iD: 0000-0003-1667-5355
SPIN-code: 1120-7630

MD, Dr. Sci. (Med.), Prof., Director, N.V. Sklifosovsky Institute of Clinical Medicine

Russian Federation, Moscow

Dmitry S. Petelin

First Moscow State Medical University named after I.M. Sechenov

Author for correspondence.
Email: petelinhome1@yandex.ru
ORCID iD: 0000-0002-2228-6316
SPIN-code: 4426-2811

MD, Cand. Sci. (Med.), Assistant, Depart. of Psychiatry and Psychososmatics, N.V. Sklifosovsky Institute of Clinical Medicine

Russian Federation, Moscow

Daria S. Ponomareva

Center for Cognition and Decision Making, Institute for Cognitive Neuroscience, HSE University

Email: dsponomareva_1@edu.hse.ru
ORCID iD: 0009-0004-3871-9763

Master Student

Russian Federation, Moscow

Mikhail I. Salamatin

Center for Cognition and Decision Making, Institute for Cognitive Neuroscience, HSE University

Email: mihail.salamatin@gmail.com
ORCID iD: 0009-0004-1063-5509

Master Student

Russian Federation, Moscow

Artyom A. Batov

Center for Cognition and Decision Making, Institute for Cognitive Neuroscience, HSE University; First Moscow State Medical University named after I.M. Sechenov

Email: batov3003t@gmail.com
ORCID iD: 0000-0002-1153-9947

Specialist Student

Russian Federation, Moscow; Moscow

Matteo Feurra

Center for Cognition and Decision Making, Institute for Cognitive Neuroscience, HSE University

Email: mfeurra@hse.ru
ORCID iD: 0000-0003-0934-6764

Assoc. Prof., Institute for Cognitive Neuroscience

Russian Federation, Moscow

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2. Fig. 1. Literature selection system.

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3. Fig. 2. Prevalence of year of publication of articles.

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4. Fig. 3. Frequency of occurrence of the most common words in English literature.

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5. Fig. 4. Frequency of occurrence of the most common words in Russian-language literature (some of the abstracts of Russian-language articles were given in English).

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