Complex research herb of the Fragrant violet growing in the North Caucasus and ways of its use
- 作者: Yakovleva S.G.1, Yurtaeva E.A.2, Stepanova E.F.2, Kovtun E.V.2, Pogrebnyak L.V.2, Tatarenko-Kozmina T.Y.3,4, Pleten A.P.4
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隶属关系:
- Pyatigorsk Medical and Pharmaceutical Institute – branch of the Federal State Budgetary Educational Institution of Higher Education Volgograd State Medical University of the Ministry of Health of Russia
- Pyatigorsk Medical and Pharmaceutical Institute – branch of the Volgograd State Medical University of the Ministry of Health of Russia
- Scientific Research Institute of Clinical Medicine named after Semashko
- Moscow State Medical and Dental University named after A.I. Evdokimov of the Ministry of Health of the Russia
- 期: 卷 27, 编号 4 (2024)
- 页面: 36-41
- 栏目: Pharmaceutical chemistry
- URL: https://journals.eco-vector.com/1560-9596/article/view/631279
- DOI: https://doi.org/10.29296/25877313-2024-04-05
- ID: 631279
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Introduction. Fragrant violet (Viola odorata L., family Violaceae) is a perennial herbaceous plant, widespread in the North Caucasus and the European part of Russia. The aerial part of the plant contains various active biologically active substances, such as phenolic and triterpene glycosides, polysaccharides, phenolic compounds, coumarins and flavonoids, ascorbic acid, macro and microelements, which are responsible for its medicinal properties. In modern herbal medicine, fragrant violet is used as an anti-inflammatory, analgesic, antioxidant, diuretic, antihypertensive and antibacterial agent. However, further research is needed to confirm these medicinal properties.
Objectives. Preparation of a dry extract from the herb violet fragrant and evaluation of its antibacterial activity against the clinical strain of Staphylococcus aureus III.
Material and methods. The object of the study was a dry extract from the herb of fragrant violet, collected on the territory of three municipalities of the Stavropol Territory in the flowering phase of 2020-2022, obtained by exhaustive extraction with 70% ethyl alcohol. For microbiological studies, the serial dilution method was used. Meat-peptone broth (MPB) was used as a control, without adding a suspension of microorganisms to control the sterility of the environment and with the addition of microorganisms to control the growth of the microorganism, as well as a number of serial dilutions of the reference drug: “Ceftriaxone”. Results. It was established that the studied extract from fragrant violet has antibacterial properties, which is confirmed by the identified bacteriostatic effect (reduction in the number of colonies formed compared to the control) and a change in the cultural properties of the colonies relative to the control.
Conclusions. The obtained screening results actualize further study of the extract from the herb violet fragrant in relation to representatives of opportunistic flora and the prospects of its use as an antimicrobial and anti-inflammatory agent of plant origin.
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作者简介
S. Yakovleva
Pyatigorsk Medical and Pharmaceutical Institute – branch of the Federal State Budgetary Educational Institution of Higher Education Volgograd State Medical University of the Ministry of Health of Russia
Email: elena.f.73@mail.ru
Ph.D. (Pharm.), Associate Professor of the Department of Pharmacognosy, Botany and Technology of Phytopreparations
俄罗斯联邦, PyatigorskE. Yurtaeva
Pyatigorsk Medical and Pharmaceutical Institute – branch of the Volgograd State Medical University of the Ministry of Health of Russia
Email: elena.f.73@mail.ru
Ph.D. (Pharm.), Associate Professor, Department of Microbiology and Immunology
俄罗斯联邦, PyatigorskE. Stepanova
Pyatigorsk Medical and Pharmaceutical Institute – branch of the Volgograd State Medical University of the Ministry of Health of Russia
Email: elena.f.73@mail.ru
Dr.Sc. (Pharm.), Professor, Professor of the Department of Pharmaceutical Technology with a Course of Medical Biotechnology
俄罗斯联邦, PyatigorskE. Kovtun
Pyatigorsk Medical and Pharmaceutical Institute – branch of the Volgograd State Medical University of the Ministry of Health of Russia
编辑信件的主要联系方式.
Email: elena.f.73@mail.ru
Ph.D. (Pharm.), Associate Professor, Department of Pharmaceutical Technology with Medical Biotechnology
俄罗斯联邦, PyatigorskL. Pogrebnyak
Pyatigorsk Medical and Pharmaceutical Institute – branch of the Volgograd State Medical University of the Ministry of Health of Russia
Email: elena.f.73@mail.ru
Ph.D. (Pharm.), Associate Professor, Department of Pharmaceutical Technology with a Course in Medical Biotechnology
俄罗斯联邦, PyatigorskT. Tatarenko-Kozmina
Scientific Research Institute of Clinical Medicine named after Semashko; Moscow State Medical and Dental University named after A.I. Evdokimov of the Ministry of Health of the Russia
Email: elena.f.73@mail.ru
Dr.Sc. (Biol.), Professor, Head of Department of Medical Biology with the Fundamentals of Cellular and Molecular Biotechnology
俄罗斯联邦, Moscow; MoscowA. Pleten
Moscow State Medical and Dental University named after A.I. Evdokimov of the Ministry of Health of the Russia
Email: elena.f.73@mail.ru
Dr.Sc. (Biol.), Professor of the Department of Biological Chemistry
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