Study of the elemental composition of extracts from different fractions of maral antlers
- 作者: Galenko M.S.1, Safronov S.M.2, Gravel I.V.1
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隶属关系:
- I.M. Sechenov First Moscow State Medical University (Sechenov University)
- Visterra LLC
- 期: 卷 27, 编号 11 (2024)
- 页面: 80-84
- 栏目: Bioelementology
- URL: https://journals.eco-vector.com/1560-9596/article/view/642198
- DOI: https://doi.org/10.29296/25877313-2024-11-10
- ID: 642198
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Introduction. Currently, medicines based on antler raw materials are gaining popularity due to their rich biological composition and biostimulating activity. However, these drugs must be safe for medical use, so it is necessary to study their mineral composition.
The aim of the study – to determine the mineral composition, including heavy metals and arsenic in dry extracts from maral antlers.
Material and methods. The objects of the study were various fractions of maral antlers produced in a pharmaceutical factory. Mineralization of the samples was carried out by microwave decomposition. The elemental composition of the studied objects was determined by inductively coupled plasma mass spectrometry.
Results: The content of 27 elements (Li, Na, Mg, Al, P, K, Ca, Cr, Mn, Fe, Co, Ni, Cu, Zn, Ga, As, Sr, Mo, Pd, Ag, Cd, Sb, Ba, Hg, Tl, Pb, Bi) in the studied extracts was determined. Manganese, silver, cadmium, mercury, thallium, bismuth were not detected in the samples, the content of 21 elements was in the range of 0.009 – 70740,912 mg / kg, the amounts of toxic elements (Pb, Cd, As, Hg) were from 0 to 1.741 mg / kg. Calcium, phosphorus, sodium and potassium were found in the largest quantities, iron and copper were the microelements, and cobalt, molybdenum and arsenic were found in the smallest quantities. The maximum number of elements was contained in the bone-mineral component, and the minimum in the water-protein component. This is due to the biological characteristics of the original medicinal raw material.
Conclusion. The results of the study are consistent with the literature data. The possible intake of minerals into the human body was calculated when consuming extracts from different fractions of maral antlers. It was found that the number of elements does not exceed the upper permissible levels of daily consumption and the extracts are safe for medical use.
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作者简介
M. Galenko
I.M. Sechenov First Moscow State Medical University (Sechenov University)
编辑信件的主要联系方式.
Email: marta.galenko@mail.ru
ORCID iD: 0000-0002-9050-5947
Applicant of the Department of Pharmaceutical Natural Science, Institute of Pharmacy
俄罗斯联邦, MoscowS. Safronov
Visterra LLC
Email: director@visterra.ru
Ph.D. (Chem.), General Director
俄罗斯联邦, AltayskoeI. Gravel
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Email: gravel_i_v@staff.sechenov.ru
ORCID iD: 0000-0002-3735-2291
Dr. Sc. (Pharm.), Professor of the Department of Pharmaceutical Natural Science, Institute of Pharmacy
俄罗斯联邦, Moscow参考
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