Comparative evaluation of the efficiency of the impact of Aquashine line preparations on skin fibroblasts under aging in vitro (cell-molecular research)
- Authors: Polyakova V.O1,2, Gazitaeva Z.I3,4, Kleimenova T.S1,5, Drobintseva A.O1,5, Prokopov A.Y.6, Kvetnoy I.M1,2
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Affiliations:
- Ott Research Institute of Obstetrics, Gynecology, and Reproductology
- St. Petersburg State University
- Institute of Beauty «Fijie»
- St. Petersburg Institute of Bioregulation and Gerontology
- St. Petersburg State Pediatric Medical University
- ROS-Chemistry Laboratory
- Issue: Vol 17, No 3 (2019)
- Pages: 37-42
- Section: Articles
- URL: https://journals.eco-vector.com/1728-2918/article/view/113094
- DOI: https://doi.org/10.29296/24999490-2019-03-07
- ID: 113094
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Abstract
Introduction. Skin aging is a natural process that cannot be stopped. However, there are many ways to help stop premature aging of the skin and reduce the signs that have already appeared. One of them is the subcutaneous administration of preparations containing biomimetic peptides capable of interacting with growth factor receptors and providing an anti-aging clinical effect. The purpose of this study was to compare the geroprotective properties of the preparations Aquashine and Aquashine HA. Methods. To study the aging of skin fibroblasts in culture, the cell culture method was used, and immunocytochemistry and confocal microscopy were used to identify markers of aging. Results. The preparation Aquashine HA has the ability to activate proliferative processes in the skin, and, by virtue of its properties, regulates the processes of cell renewal through increased cell apoptosis. Conclusion. Aquashine HA has a more pronounced geroprotective effect compared to Aquashine.
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About the authors
V. O Polyakova
Ott Research Institute of Obstetrics, Gynecology, and Reproductology; St. Petersburg State University
Z. I Gazitaeva
Institute of Beauty «Fijie»; St. Petersburg Institute of Bioregulation and Gerontology
T. S Kleimenova
Ott Research Institute of Obstetrics, Gynecology, and Reproductology; St. Petersburg State Pediatric Medical University
A. O Drobintseva
Ott Research Institute of Obstetrics, Gynecology, and Reproductology; St. Petersburg State Pediatric Medical University
Email: anna.drobintseva@gmail.com
A. Yu Prokopov
ROS-Chemistry Laboratory
I. M Kvetnoy
Ott Research Institute of Obstetrics, Gynecology, and Reproductology; St. Petersburg State University
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