Open Access Open Access  Restricted Access Access granted  Restricted Access Subscription or Fee Access

No 1 (2011)


Diagnosis and treatment of urolithiasis in combination with infravesical obstruction in presenile and senile patients

Trapeznikova M.F., Dutov V.V., Gal'ko A.A., Rumyantsev A.A., Zlobin A.N., Belyaev V.V., Shvedov M.Y., Trapeznikova M.F., Dutov V.V., Galko A.A., Rumyantsev A.A., Zlobin A.N., Belyaev V.V., Shvedov M.Y.


The analysis of the results of examination and treatment of 510 urolithiasis patients with organic infravesical obstruction (IVO) treated in the urological clinic of M.F. Vladimirsky Moscow Regional Research Clinical Institute and in the urological department of Zhukovsky city hospital from 1995 to 2009 made it possible to arrive at the following conclusions: the above patients have obstruction symptoms in 100% cases, irritative symptoms - in more than 2/3 of the patients; combined use of low invasive, endoscopic and open methods reestablishes urodynamics of the lower urinary tract in more than 90% patients; the decision on the treatment policy and techniques depends on severity of clinical symptoms caused by IVO and urolithiasis as well as disturbance of upper and lower urinary tract urodynamics. In adequate choice of the patients and correct indications combined use of low invasive, endoscopic and open methods provides good treatment effect in patients with IVO and urolithiasis.
Urologiia. 2011;(1):3-6
pages 3-6 views

Effects of water regimens on crystallization intensity in experimental nephrolithiasis

Bryukhanov V.M., Zverev Y.F., Lampatov V.V., Zharikov A.Y., Kudinov A.V., Motina N.V., Bryukhanov V.M., Zverev Y.F., Lampatov V.V., Zharikov A.Y., Kudinov A.V., Motina N.V.


We studied effects of water regimens on crystallization efficacy in experimental nephrolithiasis on 3 groups of Wistar male rats with initial experimental nephrolithiasis (ethylene glycol model). The animals were on free, limited and supernormal liquid intake regimen. For 3 weeks each 3-4 days we estimated 24-h diuresis, urine concentration of calcium, phosphate and oxalate ions. After 3 weeks we made a morphological examination of the kidneys. We found that limited drinking leads to an increase in urinary concentrations of oxalate- and phosphate ions which stimulate enhanced formation of calcium-containing concrements. More water intake considerably reduces oxalate and phosphate concentrations in the urine resulting in reduction of the number and size of calcium deposits in renal tissue. Thus, low liquid intake leads to intensification of urine oversaturation causing formation of renal concrements. Much liquid intake weakens oversaturation and reduces the number and size of calcium deposits in the kidneys.
Urologiia. 2011;(1):6-11
pages 6-11 views

Urinary inflammation after polytrauma: pathogenesis and treatment

Donskov V.V., Startsev V.Y., Movchan K.N., Polyushkin S.V., Donskov V.V., Startsev V.Y., Movchan K.N., Polyushkin S.V.


Urinary tract infectious-inflammatory complications frequently occur after polytrauma. Among many causes of such complications is low resistance to infection. Addition of the immunomodulator cycloferon to combined treatment of polytrauma improves prophylaxis and treatment of acute pyelonephritis in patients with combined trauma.
Urologiia. 2011;(1):11-13
pages 11-13 views

Efficacy and safety of cefixim and ciprofloxacin in acute cystitis (a multicenter randomized trial)

Galkin V.V., Malev I.V., Dovgan' E.V., Kozlov S.N., Rafal'skiy V.V., Galkin V.V., Malev I.V., Dovgan E.V., Kozlov S.N., Rafalsky V.V.


A prospective multicenter randomized trial enrolled 104 females aged 18-55 years with acute un-complicated cystitis. The patients were randomized into two groups: 49 patients of group 1 received cefixim in a single dose 400 mg/day for 5 days; 55 patients of group 2 were given ciprofloxacin in a dose 250-500 mg twice a day for 5 days. Clinical and microbiological assessment of efficacy and safety was made before treatment and on treatment day 8 and 28. Significant differences were found between groups 1 and 2 in parameters of bacteriological and clinical efficacy. Eradication of the agent and persistent bacteriological response was seen in 95.9 and 100% patients of group 1, 66 and 100% patients of group 2, respectively. Complete and partial response was observed in 55.1 and 75.5% patients of group 1, 37.3 and 58.1% patients of group 2, respectively. Thus, cefixim in a single dose 400 mg/day for 5 days has a higher microbiological efficacy than ciprofloxacin in a dose 250-500 mg twice a day. Side effects occurred less frequently in the treatment with cefixim.
Urologiia. 2011;(1):13-16
pages 13-16 views

Treatment of patients with resistant urogenital infection

Kul'chavenya E.V., Breusov A.A., Kulchavenya E.V., Breusov A.A.


In our trial 43 patients with urogenital infections resistant to standard therapy received the same basic therapy (4 tablets of safocid a day for 5 days) which, on demand, was combined with pathogenetic and symptomatic treatment. The effect was achieved by both subjective and objective parameters: pathogenic microflora was not detected after 10 days in 39 (90.7%) patients; none of the patients discharged protozoa, fungi. Tests for chlamidia were negative in all the carriers in 2 months, for ureaplasma - in 94.1% males and 83.3% females, respectively. A significant response was observed in 38 of 43 (88.4%) patients, improvement was seen in 5 (11.6%) patients. The above results persisted for 2 months of follow-up.
Urologiia. 2011;(1):17-21
pages 17-21 views

Treatment of prostatic adenoma with comorbid chronic bacterial prostatitis

Davidov M.I., Davidov M.I.


A randomized trial of efficacy and safety of vitaprost plus and vitaprost forte has been made in 70 patients with prostatic adenoma comorbid with chronic bacterial prostatitis. The patients were randomized into two groups: group 1 patients received vitaprost plus in rectal suppositoria for 1 months, then vitaprost forte for 2 months; group 2 patients (control) received gentos and lomefloxacin per os. Short- and long-term results were evaluated in 3 and 6 months. By all parameters group 1 achieved better treatment results than controls. Immediate positive response was observed in 97.1% patients, long-term positive effects were observed in 85.7%. Total points of prostatic adenoma symptoms reduced by 37%, chronic prostatitis - by 55%, residual urine diminished by 66%, Qmax increased, quality of life improved by 45%, sexual function enhanced. Size of the prostate decreased by 7.4 cm3, leukocyte count in prostatic secretion fell 6-fold, eradication of prostatitis causing agent was achieved in 3 m onths in 80% patients. Side effects and complications were not registered. Thus, vitaprost plus and vitaprost forte are highly effective and safe for treatment of patients with combination of prostatic adenoma with chronic bacterial prostatitis.
Urologiia. 2011;(1):21-28
pages 21-28 views

Alfusozine treatment of prostatic adenoma: efficacy in relation to sexuality

Kogan M.I., Kireev A.Y., Kogan M.I., Kireev A.Y.


Blood levels of total PSA and testosterone, size of the prostatic gland, Qmax were measured in 40 patients with prostatic adenoma symptoms treated with alfusozine in a dose 10 mg/day before the treatment, on the treatment week 4, 12 and 24. At the same time the examinees were questioned using IPSS, MSHQ, IIEF questionnaires. The sexuality phenotype was estimated according to the Rostov Questionnaire of Integral Male Sexuality. It was found that sexuality phenotypes (hypo-, normo- and hypersexuality) occur with the same frequency in males with prostatic adenoma symptoms. Hypersexual men with prostatic adenoma have more definite lower urinary tract symptoms, worse erection and ejaculation, more frequent signs of hypogonadism. The highest alfusozine efficacy was observed in normo- and hyposexual men with prostatic adenoma who achieved better results in improvement of Qmax, symptoms of the lower urinary tract, erectile and ejaculation function. The treatment efficacy in the hypersexual men is low.
Urologiia. 2011;(1):28-31
pages 28-31 views

Structural and functional properties of erythrocytes, endothelial dysfunction and lipid peroxidation in patients with prostatic adenoma and comorbid chronic prostatitis

Shatokhin M.N., Teodorovich O.V., Konoplya A.I., Dolgareva S.A., Gavrilyuk V.P., Shatokhin M.N., Teodorovich O.V., Konoplya A.I., Dolgareva S.A., Gavrilyuk V.P.


Patients with prostatic adenoma combined with chronic prostatitis were found to have abnormal content of proteins in peripheral blood erythrocytic membrane, erythrocytic sorption, concentration of nitric oxide stable metabolites, endotheline-1 and lipid peroxidation products in blood plasma before and after transurethral resection of the prostate. Different dosage forms of the drug longidase were tested for efficacy in correction of impairment of structural and functional properties of erythrocytes, endothelial dysfunction and lipid peroxidation in the above patients.
Urologiia. 2011;(1):31-34
pages 31-34 views

The role of ACE gene polymorphism in development of erectile dysfunction in patients with metabolic syndrome

Gamidov S.I., Iremashvili V.V., Nosikov V.V., Gamidov S.I., Iremashvili V.V., Nosikov V.V.


To ascertain relations between angiotensin converting enzyme (ACE) gene polymorphism and erectile dysfunction (ED) in male citizens of Russia with metabolic syndrome, we made a retrospective comparative analysis of ACE gene polymorphism incidence rate in two groups of males with metabolic syndrome: with ED (n = 385) and free of ED (n = 152). We discovered that ED patients have DD genotype and D-allele more frequently (68.3 vs 38.2%, p < 0.001 and 81.3 vs 63.8%, p < 0.001, respectively). Moreover, severe ED is associated with significantly more frequent incidence of genotype DD compared to moderate and mild ED. Incidence of allele D is also more frequent in patients with severe ED (93.4%). Thus, D-allele of ACE gene is an ED risk factor in males with metabolic syndrome. Therefore, ED can be considered as one of vascular complications of metabolic syndrome.
Urologiia. 2011;(1):34-37
pages 34-37 views

Transurethral holmium enucleation of prostatic adenoma

Martov A.G., Maksimov V.A., Yarovoy S.Y., Ergakov D.V., Kornienko S.I., Fakhredinov G.A., Martov A.G., Maximov V.A., Yarovoi S.Y., Ergakov D.V., Kornienko S.I., Fahredinov G.A.


Laser (holmium) enucleation of the prostate (LEP) for infravesical obstruction caused by prostatic adenoma up to 60 cm3 in size was made in 42 patients in the Moscow city urological hospital N 47 from January to July 2009. Transurethral resection (TUR) of the prostate was made in 42 matched controls. All the patients from both groups have undergone the same standard clinical and laboratory examination before the treatment, 1, 3 and 6 months after it. Duration of surgery was shorter in the TUR group (42.4±26.1 min vs 74.8±39.7 min). Washing system operated longer in the TUR group (23±7 vs 10±5 h). The LEP group patients stayed in the hospital for much shorter time (3.1±1.2 days vs 4.6±1.8 days). No significant differences between the groups by basic postoperative parameters were found 1, 3 and 6 months after the operation. Postoperative complications were rare in both groups. Hemorrhagic complications were absent in the LEP group. This makes it possible to recommend LEP for patients with coagulopathy. Trauma of the bladder occurred in 1 case of LEP because of a complicated technique of LEP and the absence of conventional endoscopic reference points characteristic for TUR. Thus, our initial experience with transurethral LEP in comparison with TUR leads us to the conclusion that LEP is effective and safe in surgical treatment of patients with prostatic adenoma. Further gain of experience with LEP conduction may make this method alternative to open adenomectomy.
Urologiia. 2011;(1):38-43
pages 38-43 views

Prophylaxis of early postoperative complications after transurethral prostatic resection (an experimental study)

Volkov D.Y., Artifeksov S.B., Artifeksova A.A., Volkov D.Y., Artifeksov S.B., Artifeksova A.A.


Modelling of transurethral resection (TUR) of the prostate on the animals has shown that changes in the region of postoperative wound progress by inflammatory stages - primary, then secondary alteration. These changes are confirmed by the morphological picture, shifts in enzyme levels, findings of the spectral analysis typical for systemic inflammatory reaction. Approaches to prevention of early postoperative complications based on principal components of pathogenesis are proposed.
Urologiia. 2011;(1):44-46
pages 44-46 views

Urinary bladder hemangiomas in children: experience with endoscopic treatment

Abdullaev F.K., Nikolaev V.V., Kulaev V.D., Cherkashina E.N., Abdullaev F.K., NIkolaev V.V., Kulaev V.D., Cherkashina E.N.


Urgent arrest of bleeding is often required in hemangiomas. Endoscopic photocoagulation withNe YAG-laser was applied in the department of urology of the Central Children's Hospital in Moscow to arrest bleeding in 5 children (2 boys and 3 girls aged 3-12 years) with hemangioma of the bladder in 1998-2009. In 3 cases the tumors were solitary (up to 5 cm), in 2 cases (multiple small 1-3 cm). The intervention was performed in the presence of hemorrhage in 3 children. One girl had intensive bleeding in photocoagulation and urgent resection of the bladder was made. Immediate hemostasis in hemorrhage was achieved in 2 of 3 patients. After a single procedure, 2 children had no bleeding for 1 and 5 years, respectively, but they retained endoscopic picture of angiomatosis. One boy after 4 sessions of photocoagulation performed with intervals 6-13 months has no manifestations of hemangioma for 4 years. A girl with multiple hemangioma undergoes photocoagulation for recurrent macrohematuria each 8-26 months. Another girl operated for bladder hemangioma has no endoscopic signs of the tumor recurrence for 2 years. Thus, photocoagulation of bladder hemangioma is an effective method of hemostasis but probability of a late recurrent bleeding after photocoagulation is higher than in open interventions. Therefore, long-term follow-up is needed and repeated endoscopic investigations with prophylactic impact on thin-walled or erosive sites of hemangioma should be made.
Urologiia. 2011;(1):46-49
pages 46-49 views

Water-electrolyte homeostasis and hemostasis system after transurethral resection of the prostate

Muradyan A.A., Madatyan A.U., Muradyan A.A., Madatyan A.U.


Changes in coagulogram and water-electrolyte homeostasis were studied in 89 patients surgically treated for prostatic adenoma (TUR). The patients were divided into 2 groups: group 1 (n = 21) was operated with use of distilled water, group 2 - with 5% glucose solution. The following examinations were made in all the patients: extended coagulogram, total blood count, concentration of electrolytes, creatinin, plasma urea and glucose, osmolality measurements. These were made thrice: before the operation, on postoperative day 1, postoperative day 3. Postoperative changes of hemostasis and water-electrolyte homeostasis of plasma were less significant in group 2. The risk of postoperative hemorrhage is higher in patients of group 1.
Urologiia. 2011;(1):50-53
pages 50-53 views

A giant Buschke-Lowenstein condiloma

Larionov I.N., Belozerov N.Y., Romanov G.V., Uglova N.V., Larionov I.N., Belozerov N.Y., Romanov G.V., Uglova N.V.
Urologiia. 2011;(1):54-56
pages 54-56 views

A successful treatment of external ileac artery stenosis in a woman after kidney transplantation

Yankovoy A.G., Vatazin A.V., Astakhov P.V., Budarina E.Y., Demidov I.N., Stepanov V.A., Yankovoi A.G., Vatazin A.V., Astakhov P.V., Budarina E.Y., Demidov I.N., Stepanov V.A.
Urologiia. 2011;(1):56-59
pages 56-59 views

Pelvic prolapse

Pushkar' D.Y., Gvozdev M.Y., Malkhasyan V.A., Pushkar D.Y., Gvozdev M.Y., Malkhasyan V.A.
Urologiia. 2011;(1):59-63
pages 59-63 views

Primary obstructive megaureter of the newborns and infants: diagnosis, treatment, follow-up

Yushko E.I., Strotskiy A.V., Yushko E.I., Strotsky A.V.
Urologiia. 2011;(1):63-67
pages 63-67 views
pages 67-68 views
pages 68-68 views

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies