Efficiency of differention immunotherapy in HBS-antigen and chronic hepatitis B virus carriers

Using technique worked out by the authors, the immune disorders in HBS-antigen and chronic hepatitis B virus carriers were analysed. In such patients typical changes of immunolaboratory parameters develop. The changes are marked in chronic hepatitis B virus carriers and accompanied by modified liver tunction of dexofication. The administration of anti-viral vaccine in HBC-antigen carriers improves the immunolaboratory status which becomes more noticeable when modulators such as derinate and especially sodium nucleinate are used. The basic treatment of patients with chronic hepatitis B yirus vields marked improvement of the parameters under study. Special vaccines may make this effect more noticeable. Among the administered adjuvants derinate proved to be most effective.