The changes of immune homeostasis at patientswith gastroesophageal reflux disease and Barrett'sEsophagus
- Authors: Kozlova IV1, Lipatova TE1, Shuman Mohamad Ali Trad -1
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- Issue: Vol 3, No 2 (2006)
- Pages: 27-32
- Section: Articles
- URL: https://journals.eco-vector.com/1994-9480/article/view/117804
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Abstract
The purpose of the research was the study of cellular immune status and serum cytokines at patients with gastroesophageal reflux disease (GERD) and Barrett's esophagus. We have studied 70 patients with erosive GERD and 42 patients with Barrett's esophagus. 30 patients with chronic gastritis and 25 healthy subjects comprised the groups of control. Endoscopy, morphological, immunological methods of research have been used. Distinctions in parameters of cellular immune status and serum level of interleukin-4, interleukin-8, interleukin-10 and tumor necrosis factor-alpha at patients with GERD in dynamics of treatment and patients with Barrett's esophagus were determined.
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