EFFECT OF SOME NEUROTROPIC SUBSTANCES ON OXYGEN CONSUMPTION IN MITOCHONDRIA OF RAT BRAIN
- Authors: Yasnetsov V.V.1, Yasnetsov VV1
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Affiliations:
- Issue: Vol 6, No 2 (2009)
- Pages: 72-73
- Section: Articles
- URL: https://journals.eco-vector.com/1994-9480/article/view/118047
- ID: 118047
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Abstract
It was estimated by polarographic measurement of oxygen consumption in rat brain mitochondria that a new substance
IBCP-2 (in about a half of all cases), mexidol and amtizol succinate can nearly equally increase oxygen consumption. Other
new substances IBCP-1 and IBCP-3 as well as amtizol and emoxipin, have no such ability. Unlike preparations including
succinate (mexidol and amtizol succinate), IBCP-2 stimulates mitochondrial respiration by way of complex I.
IBCP-2 (in about a half of all cases), mexidol and amtizol succinate can nearly equally increase oxygen consumption. Other
new substances IBCP-1 and IBCP-3 as well as amtizol and emoxipin, have no such ability. Unlike preparations including
succinate (mexidol and amtizol succinate), IBCP-2 stimulates mitochondrial respiration by way of complex I.
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