Vol 6, No 2 (2009)

Articles

UP-TO-DATE INFORMATION ON THE ISSUE OF SURGICAL TREATMENTOF THE FOREFOOT DEFORMATIONS

Petrov D.Y., Teterin O.G., Malanin D.A., Gunin K.V., Lemeshkin S.S., Chernyavskiy M.A., Makarov A.D., Petrov D.Y., Teterin O.G., Malanin D.A., Gunin K.V., Lemeshkin S.S., Chernyavsky M.A., Makarov A.D.

Abstract

Methods of the surgical treatment of the forefoot deformation (osteotomy, operations on the soft tissues and mixed operations) are described.
Journal of Volgograd State Medical University. 2009;6(2):3-6
pages 3-6 views

INNOVATIVE TECHNOLOGIES IN RESTORATION OF DAMAGEDOR DISEASED KNEE JOINT

Malanin D.A., Novochadov V.V., Samusev S.R., Teterin O.G., Suchilin I.A., Zhulikov A.L., Malanin D.A., Novochadov V.V., Samusev S.R., Teterin O.G., Suchilin I.A., Julikov A.L.

Abstract

This review discusses present-day approaches to treatment of articular cartilage damages using autologous chondrocyte transplantation method (ACT). There are clinical and experimental studies based on evidence based medicine demonstrating the possibilities of clinical application of ACT.
Journal of Volgograd State Medical University. 2009;6(2):7-13
pages 7-13 views

CRISIS OF HEALTH AND MORTALITY INDICES IN RUSSIA AND POSSIBLE WAYS OF OVERCOMING IT (SURVEY)

Kamruzzaman S., Plutnitskiy A.N., Avakyan A.A., Voloshina L.V., Golovina S.M., Kamruzzaman S., Plutnitskiy A.N., Avakjan A.A., Voloshina L.V., Golovina S.M.

Abstract

The essence of the present crisis of indices of health and mortality in Russia and ways of overcoming it are described. The situation calls for decisive measures aimed at decreasing the death-rate among able-bodied men, infants and mothers, bringing down disablement and morbidity. It is important to improve diagnostics of death causes to determine the priorities in their elimination.
Journal of Volgograd State Medical University. 2009;6(2):14-19
pages 14-19 views

ANALYSIS OF METHYLATION STATUS ANALYSIS OF RASSF1A, BRCA1, HIN1IN BREAST AND OVARIAN CANCER CELL LINES

Potapova A.A., Ostrovskiy O.V., Dudchenko G.P., Potapova A.A., Ostrovskiy O.V., Dudchenko G.P.

Abstract

Several tumor suppressor genes have been found to be hypermethylated in many tumor types, including breast and ovarian cancer but to be unmethylated in normal cells. Here we have examined by bisulfite sequencing the methylation status of the following tumor-suppressor genes: RASSF1A, BRCA1 and HIN1. For this study we used genomic DNA from five different breast cancer cell lines (MDA231, MDA435, MCF7, T47D, HS-578T) and five different ovarian cancer cell lines (A2780, SKOV3, OVCAR10, OVCAR5, OVCAR3) as well as from normal tissue. We found promoter region of RASSF1A and HIN1 to be hypermethylated in several cancer cell lines in both types of cancer. At the same time the promoter region of BRCA1 was unmethylated in all analyzed cancer cell lines.
Journal of Volgograd State Medical University. 2009;6(2):20-22
pages 20-22 views

COMBINED PLASTY OF DEFECTS OF CRANIAL VAULT IN COMPLEX TREATMENT OF PATIENTS WITH LOCALLY-ADVANCED SKIN CANCER

Dashkova I.R., Irkhina A.N., Dashkova I.R., Irkhina A.N.

Abstract

Combined reparative surgery is most acceptable in view of its relative simplicity and convenience in replacement of anatomically complex and very extensive defects of skin occurring after excision of advanced tumours of the scalp. We have applied this method when all other plastic operations failed, in cases of extensive skin lesions with infiltration of underlying tissues, i.e. in cases presenting technical limit of possible excision. Complete engraftment in combined plastic surgery is possible even in cases of vast excision of tumour with ablation of underlying bone.
Journal of Volgograd State Medical University. 2009;6(2):23-26
pages 23-26 views

HEALTH-RESOR FACTORS OF THE TINAKI REHABILLITATION CENTEIN THE TREATMENT OF GYNECOLOGIC PATIENTS

Kuz'mina M.A., Ipatova M.V., Sinchikhin S.P., Navruzova Z.T., Kuzmina M.A., Ipatova M.V., Sinchikhin S.P., Navruzova Z.T.

Abstract

The paper present facts of effectiveness and pathogenetic substantiation of natural physical factors (sulfide-sludge mud and iodide-bromine waters) of the Tinaki Rehabillitation Center, in the treatment of women with chronic inflammatory diseases of small pelvis.
Journal of Volgograd State Medical University. 2009;6(2):26-29
pages 26-29 views

INVESTIGATION OF DEVELOPMENT OF ADDICTIVE BEHAVIOURIN SENIOR HIGH SCHOOL ADOLESCENTS

Lifanova E.V., Verstakova O.E., Budnikov M.Y., Lifanova E.V., Verstakova O.E., Budnikov M.Y.

Abstract

This paper is devoted to investigation of psychophysiological correlates of addictive behaviour in senior high school adolescents and development of individual algorithm of practical use for increasing adaptation potential, decreasing anxiety, increasing emotional stability, enhancement of cognitive functions, optimization of central nervous system functioning, balancing of autonomic nervous system functioning.
Journal of Volgograd State Medical University. 2009;6(2):30-32
pages 30-32 views

EFFECT OF SEX AND CONSTITUTION ON DEVELOPMENT OF FOOT DISEASES IN MEDICAL STUDENTS

Mandrikov V.B., Gavrikov K.V., Klauchek S.V., Vorob'ev A.A., Perepelkin A.I., Mandrikov V.B., Gavrikov K.V., Klauchek S.V., Vorobiev A.A., Perepelkin A.I.

Abstract

Using a flatbed foot scanner we determined the correlation between anatomical and physiological condition of foot on the one hand, and sex and constitution, on the other. A hardware and software package for investigation of longitudinal and transverse foot arch was developed and implemented. This package consists of a special scanner and a program obtaining the foot image for analysis and diagnostic conclusion. 600 students of the Volgograd state medical university were observed by using this technology.
Journal of Volgograd State Medical University. 2009;6(2):33-36
pages 33-36 views

ERRORS AND COMPLICATIONS IN DIAGNOSTICS AND TREATMENTOF FOREIGN BODIES IN THE ALIMENTARY TRACT

Ovseychik M.Y., Popova I.S., Ovseichik M.Y., Popova I.S.

Abstract

An analysis was made to assess the results of treatment of 130 patients with foreign bodies swallowed into the alimentary tract. Active-conservative tactics of treatment was used for 78 patients (60 %); endoscopic removal of foreign bodies was performed in 4 patients (3 %), 48 patients underwent surgery (37 %). Complications of foreign bodies presence in the alimentary tract and different errors at stages of diagnostics and treatment were shown.
Journal of Volgograd State Medical University. 2009;6(2):36-39
pages 36-39 views

SPECIFICS OF IMMUNE STATUS IN TENAGERS WITH DIFFERENT VEGETATIVE TONUS DIRECTIONS IN YAMAL REGION

Polovodova N.S., Mal'tseva T.V., Polovodova N.S., Maltseva T.V.

Abstract

Data characterizing the specifics of immunity in native and non-native schoolchildren are presented. The examined children live in the Yamal region and are characterized by different directions of vegetative tonus. The greatest imbalance of immune-status indices was defined in sympathetico-tonic non-native europeoid children in comparison with parasympathetic children of the analogous ethnos. When comparing immunologic indices of native and non-native children, some significant differences were determined.
Journal of Volgograd State Medical University. 2009;6(2):39-42
pages 39-42 views

COMPARATIVE EFFECTIVENESS OF TRADITIONAL RELAXATIONAND BIOLOGICAL FEEDBACK METHODS IN TREATMENTOF ATTENTION-DEFICIT HYPERACTIVITY DISORDER

Tonkonozhenko N.L., Klitochenko G.V., Tonkonozhenko N.L., Klitochenko G.V.

Abstract

The research was focused on comparative effectiveness of non-medication treatment of attention-deficit hyperactivity disorder (ADHD) based on dynamic analysis of electroencephalographic findings. The method of biological feedback applying respiratory sinus arrhythmia has proved to be more effective than the method of traditional relaxation.
Journal of Volgograd State Medical University. 2009;6(2):43-45
pages 43-45 views

MONITORING, PROGNOSIS AND NEW TECHNOLOGY IN SURGICAL TREATMENT OF ULCER DISEASE

Topchiev M.A., Zav'yalov D.N., Zhidovinov A.A., Antonyan V.V., Topchiev M.A., Zavyalov D.N., Jidovinov A.A., Antonyan V.V.

Abstract

15-40 % of patients subjected to stomach resection have the postgastroresectional syndrome (dumping-syndrome, reflux-gastritis etc.). To determine the risk of dumping-syndrome in the preoperative period prognostic estimations were used, and a way of stomach resection with creation of a valve in closed apparatus of its stump was proposed, which enables one to reduce the rate of development of postgastroresectional syndrome.
Journal of Volgograd State Medical University. 2009;6(2):45-48
pages 45-48 views

DISTRIBUTION OF CELLULAR ELEMENTS IN COMPLETEPERITONEAL ADHESIONS OF EPIGASTRIUM

Barkanov V.B., Vorob'ev A.A., Poroyskiy S.V., Poluos'mak B.B., Goryachev A.N., Barkanov V.B., Vorobjev A.A., Poroysky S.V., Poluosjmak B.B., Goryachev A.N.

Abstract

A variety of cellular content and of its distribution was established on morphological analysis of complete peritoneal adhesion of epigastrium which had been dissected during cholesystectomy. These differences heavily d epended on attachment place of adhesions. The tissue in adhesion to gallbladder has relatively much mesothelium and endoteliocytes in comparison with macrophages. The adhesions to liver contained a lot of macrophages and mesothelium, but they were poorly vascularized. The adhesions to duodenum were enriched by endothelium, but few macrophages or mesothelium. Omental adhesions had many macrophages and endothelium, but little mesothelium. These data may particularly explain the differences in dynamics of adhesive process in epigastrium, and their probable sensitivity to prevention and treatment.
Journal of Volgograd State Medical University. 2009;6(2):48-51
pages 48-51 views

EFFECT OF CARDIOSELECTIVITY AND INTRINSIC SYMPATHOMIMETIC ACTIVITY OF BETA-ADRENORECEPTOR BLOCKERS ON HEART RATE VARIABILITY IN WAKING AND NARCOTIZED RATS

Sal'nikov E.V., Fateev M.M., Fedorov V.N., Sidorov A.V., Salnikov E.V., Fateev M.M., Fedorov V.N., Sidorov A.V.

Abstract

In narcotized and waking immobilized rats β-adrenoreceptor blockers led to an increase in the total heart rate variability, adaptation capability; they enhanced parasympathetic activity and decreased the sympathetic one. Increase in LF power in waking immobilized rats in the presence of β-adrenoreceptor blockers requires a comprehensive study to define more precisely the physiological role of this parameter. Among three β-adrenoreceptor blockers pindolol demonstrated the least activity compared to preparations without intrinsic sympathomimetic activity such as propranolol (most pronounced effect in narcotized rats) and bisoprolol (more effective in waking immobilized rats).
Journal of Volgograd State Medical University. 2009;6(2):52-55
pages 52-55 views

CLINICOPATHOGENETIC IMPORTANCE OF ANALYSIS OF PURINE METABOLISM ENZYME ACTIVITY IN LYMPHOCYTE LYSATES AND ERYTHROCYTES OF PATIENTS WITH OSTEOARTROSIS

Gerusov Y.I., Zborovskaya I.A., Martem'yanov V.F., Bedina S.A., Mozgovaya E.E., Gerusov Y.I., Zborovskaya I.A., Martemjanov V.F., Bedina S.A., Mozgovaya E.E.

Abstract

Activities of adenosine deaminase (ADA), adenosine monophosphate deaminase (AMPHDA) and adenin deaminase (AD) were determined depending on clinical features of the disease in lyzates of lymphocytes and erythrocytes in blood of 52 patients with ostheoarthrosis. The results of the investigation demonstrated that the greatest changes in enzymatic activity were observed in patients with synovitis and a high degree of functional insufficiency of the joints. A severe course of the disease was accompained by a considerable reduction of the activity of ADA in lymphocytes and a high activity of ADA, AMPHDA and AD in erythrocytes. Investigation of enzymatic activity promoted the control of objectivity and effectiveness of treatment.
Journal of Volgograd State Medical University. 2009;6(2):56-59
pages 56-59 views

NEUROINFORMATION TECHNOLOGIES USED IN CHRONIC OPISTHORCHOSIS DIAGNOSTICS IN ORDER TO IMPROVE LIFE QUALITY

Fedorovskiy A.F., Zasorina N.V., Karbysheva N.V., Fedorovsky A.F., Zasorina N.V., Karbischeva N.V.

Abstract

At present the incidence rate of chronic opisthorchosis among the able-bodied population is gaining a socio-economic character. Despite successful diagnostics of this condition, the problem perseveres and requires development and implementation of new, more precise and economic diagnostic methods, which help to identify an early invasion. This paper describes a new method of opisthorchosis invasion detection based on using neuronetwork techno logies. The analysis of the endoscopic view of upper gastrointestinal pathological changes yielded typical endoscopic criteria of chronic opisthorchosis. A new neuronetwork computer program was developed in accordance with these factors. This program is easy to use, economic and more effective than present screening tests.
Journal of Volgograd State Medical University. 2009;6(2):60-62
pages 60-62 views

CHANGE OF EXPRESSION OF ANGIOGENIC GROWTH FACTORS AND THEIRRECEPTORS DURING DEVELOPMENT OF INFERTILITY IN EXTERNAL GENITAL ENDOMETRIOSIS

Ermolova N.V., Ermolova N.V.

Abstract

The content of epidermal growth factor, vascular endothelial growth factor and receptors for this factors of blood serum and peritoneal fluid in patients with external genital endometriosis and infertility was investigated. An increased level of endothelin-1 in peritoneal fluid of patients of this group was revealed.
Journal of Volgograd State Medical University. 2009;6(2):63-66
pages 63-66 views

MEDICO-SOCIAL RISK FACTORS OF PROSPECTIVE CONSCRIPTS AND CONSCRIPTS

Kuznetsova O.A., Kuznetzova O.A.

Abstract

By way of anonymous questionnaires we examined a subjective estimation of health and medicosocial risk factors among juveniles aged 16-27. It was revealed that most respondents consider themselves to be healthy as well as having unfavourable social factors. Bad habits are quite prevalent. The most common bad habits are drinking and smoking. A low level of information awareness and medical competence among prospective conscripts and conscripts was reevaled.
Journal of Volgograd State Medical University. 2009;6(2):66-68
pages 66-68 views

LIFE QUALITY OF SCHOOL-AGE CHILDREN AND ITS AGE- AND GENDER-RELATED FEATURES (ACCORDING TO CHQ-87 AND SF-36)

Rychkova S.V., Rychkova S.V.

Abstract

A dependence of life quality on age and sex in children and teenagers was investigated. It is established that age dynamics of life quality is sex-related. In girls the index of life quality associated with health decreases earlier than in boys.
Journal of Volgograd State Medical University. 2009;6(2):69-71
pages 69-71 views

EFFECT OF SOME NEUROTROPIC SUBSTANCES ON OXYGEN CONSUMPTION IN MITOCHONDRIA OF RAT BRAIN

Yasnetsov V.V., Yasnetsov V.V.

Abstract

It was estimated by polarographic measurement of oxygen consumption in rat brain mitochondria that a new substance IBCP-2 (in about a half of all cases), mexidol and amtizol succinate can nearly equally increase oxygen consumption. Other new substances IBCP-1 and IBCP-3 as well as amtizol and emoxipin, have no such ability. Unlike preparations including succinate (mexidol and amtizol succinate), IBCP-2 stimulates mitochondrial respiration by way of complex I.
Journal of Volgograd State Medical University. 2009;6(2):72-73
pages 72-73 views

STRUCTURAL ALTERATIONS OF HYPOTHALAMUSIN EXPERIMENTAL MODELING OF WEST NILE ENCEPHALITIS

Glukhov V.A., Smirnov A.V., Shmidt M.V., Butenko A.M., Khutoretskaya N.V., Larichev V.F., Glukhov V.A., Smirnov A.V., Schmidt M.V., Butenko A.M., Khutoretskaya N.V., Larichev V.P.

Abstract

We modeled West Nile encephalitis by way of infecting white mice subcutaneously. Clinical symptoms of meningoencephalitis were found on the 7th day of experiment. Ultrastructural alterations in neurons, damage of myelin sheaths in the hypothalamus indicate cytopathic action of West Nile virus.
Journal of Volgograd State Medical University. 2009;6(2):74-76
pages 74-76 views

USE OF TRANSVAGINAL COLOR DOPPLER ULTRASOUND FOR PRENATALDIAGNOSIS OF VASA PREVIA

Sokolova M.S., Sokolova M.S.

Abstract

Vasa previa is a condition in which the intramembranous fetal blood vessels cross the internal os. Fetal mortality is high because of the hemorrhage that occurs when these vessels are torn during labor, delivery or when the amniofetal membranes rupture. Reduction in perinatal mortality from this condition depends on its prenatal diagnosis. А first case of color Doppler endovaginal prenatal ultrasound diagnosis of vasa previa in Russia is presented.
Journal of Volgograd State Medical University. 2009;6(2):77-78
pages 77-78 views

MORPHOFUNCTIONAL CHARACTERISTIC OF BONE FORMATION USING IMPLANTSWITH NANOSTRUCTURAL BIOCERAMIC COVERINGS (experimental research)

Kraynov E.A., Lantsov Y.A., Malanin D.A., Derevyanko I.V., Suchilin I.A., Krainov E.А., Lantsov Y.А., Malanin D.А., Derevyanko I.V., Suchilin I.A.

Abstract

Morphological and physicomechanical characteristics of neoplastic tissue on the border of «bone - implant» using various bioceramic coating are discussed in the article.
Journal of Volgograd State Medical University. 2009;6(2):78-81
pages 78-81 views

MORPHOLOGIC EVALUATION OF STRESS-RELATED CHANGESIN THE FOLLICULAR COMPARTMENT OF THYROID GLAND IN EXPOSURETO SEVERE STRESSOR

Smirnova T.S., Degtyar' Y.V., Kokin N.I., Sharaevskaya M.V., Kapitonova M.Y., Smirnova T.S., Degtyar Y.V., Kokin N.I., Sharaevskaya M.V., Kapitonova M.Y.

Abstract

Comparative evaluation of age-related structural changes in the follicular compartment of the thyroid gland under severe stress conditions is provided in the article.
Journal of Volgograd State Medical University. 2009;6(2):82-84
pages 82-84 views

ANTIBIOTIC THERAPY OF COMPLICATED NONHOSPITAL PNEUMONIA(clinicoeconomic analysis)

Molchanova O.V., Suleymanov S.S., Ostrovskiy A.B., Repina G.D., Shchennikov E.L., Molchanova O.V., Suleymanov S.S., Ostrovsky A.B., Repina G.D., Schennikov E.L.

Abstract

In treatment of complicated nonhospital pneumonia antibiotic therapy has advantages both from the point of view of medicine and economy: beta lactam [cefotaxim intravenously] in combination with macrolides [azithromycin].
Journal of Volgograd State Medical University. 2009;6(2):85-87
pages 85-87 views

EARLY RHEUMATOID ARTHRITIS: CONCEPT OF EARLY DIAGNOSTICS AND TREATMENT

Babaeva A.R., Cherevkova E.V., Solodenkova K.S., Babaeva A.R., Tcherevkova E.V., Solodenkova K.S.

Abstract

This review provides novel information on pathogenesis, clinical characteristics, diagnostic and therapeutic approaches to early rheumatoid arthritis. TA possibility of affecting the natural course of this disease using early, aggressive disease-modifying antirheumatic therapy is discussed. Rapid and sustained disease control with biologics was shown in recent placebo-controlled studies. The novel original preparations containing ultra-low doses of antibodies against tumor necrosis factor-a (TNF-a) and interferon-g (INF-g) were approved for rheumatoid arthritis treatment. Our previous investigations have confirmed good efficacy and safety of ultra-low anti-TNF-a preparation (artrofoon) and its combination with ultra-low anti-INF-g (anaferon) in long-term rheumatoid arthritis therapy. The possibility of preventing disease progression prevention using these drugs in early rheumatoid arthritis should be assessed.
Journal of Volgograd State Medical University. 2009;6(2):88-93
pages 88-93 views

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