THE REINFORCEMENT OF RENIN-ANGEOTENSIN-ALDOSTERON SYSTEMBLOCKAGE: COMPARISON OF THE RESULTS OF THE MONOTHERAPYBY CARDOSTEN AND THE COMBINATION OF CARDOSTEN AND ENALAPRILAMONG THE PATIENTS WITH ARTERIAL HYPERTENSION IN COMBINATIONWITH METABOLIC SYNDROME
- Authors: Frolova EV1, Avdienko AA1, Frolova EV1, Avdienko AA1
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Affiliations:
- Issue: Vol 6, No 4 (2009)
- Pages: 90-92
- Section: Articles
- URL: https://journals.eco-vector.com/1994-9480/article/view/118078
- ID: 118078
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Abstract
We studied the possibility of extra blockage of renin-angeotensin-aldosteron system as a result of combined therapy
by ultra small doses of antibodies to C-end fragment of AT-1 receptor of angiotensin II cardosten and angiotensin-converting
enzyme inhibitor among patients with the first degree arterial hypertension in combination with metabolic syndrome. The angiotensin-converting enzyme inhibitor enalapril supplement in dose of 10 mg two times a day to the monotherapy by cardosten speeds up and strengthens the hypotensive effect, it favorably influences on the data of lipid and carbohydrate
metabolism during first three months of treatment. Further the phenomenon of recession effect develops and the results
of treatment aren't different from the monotherapy by cardosten.
by ultra small doses of antibodies to C-end fragment of AT-1 receptor of angiotensin II cardosten and angiotensin-converting
enzyme inhibitor among patients with the first degree arterial hypertension in combination with metabolic syndrome. The angiotensin-converting enzyme inhibitor enalapril supplement in dose of 10 mg two times a day to the monotherapy by cardosten speeds up and strengthens the hypotensive effect, it favorably influences on the data of lipid and carbohydrate
metabolism during first three months of treatment. Further the phenomenon of recession effect develops and the results
of treatment aren't different from the monotherapy by cardosten.
References
- Беленков Ю. Н., Оганов Р. Г. Кардиология. Национальное руководство. - М.: Гэотар-Медиа, 2007. - С. 611-624.
- Беленков Ю. Н., Чазова И. Е., Мычка В. Б. // Артеральные гипертензии. - 2003. - № 96. - С. 196-199.
- Гороховская Г. Н., Чернецова Е. В., Петина М. М. Принципы диагностики и лечения метаболического синдрома. - М., 2008. - С. 22-24.
- Мамедов М. Н., Косматова О. В., Чудакова И. В. и др. // Сердце. - 2006. - Т. 5, № 3 (27). - С. 129-133.
- Чазова И. Е., Мычка В. Б. Метаболический синдром. - М.: Media Medica, 2004.
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