CLINICAL AND PATHOGENETIC SIGNIFICANCE OF SERUM RESISTIN DETERMINATION IN OSTEOARTHRITIC PATIENTS


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Abstract

Thе present study shows that resistin may have an important significance in pathogenesis of ОА. Osteoarthritic patients with high serum resistin level have a more aggressive form of the disease. In this study serum resistin was clearly elevated and strongly correlated with systemic inflammation and functional impairment in OA. Thus, serum resistin could be used as a marker of OA progression.

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Copyright (c) 2011 Popov D.A., Zavodovsky B.V., Sivordova L.E., Fofanova N.A., Zborovskaya I.A.

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