Clinical significance of investigation of purine metabolismenzyme activity in patients with systemic scleroderma
- Authors: Karpova OV1, Rybak VA1, Karpova OV1, Rybak VA1
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Affiliations:
- Issue: Vol 4, No 1 (2007)
- Pages: 58-61
- Section: Articles
- URL: https://journals.eco-vector.com/1994-9480/article/view/140050
- ID: 140050
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Abstract
The activity of xanthine oxidase, xanthine dehydrogenase and 5'-nucleotidases in lymphocyte lysates and
blood plasma was studied in 50 patients with systemic scleroderma upon admission to hospital, after 10-12 days of treatment
and on completion of the inpatient care course.
Considerable changes of enzyme activity depending on the intensity of pathologic process, the nature of the clinical
course and the stage of disease were clearly recognizable. As the activity of the process increased, the enzyme activity
reduced in lymphocyte lysate and rose in blood plasma.
blood plasma was studied in 50 patients with systemic scleroderma upon admission to hospital, after 10-12 days of treatment
and on completion of the inpatient care course.
Considerable changes of enzyme activity depending on the intensity of pathologic process, the nature of the clinical
course and the stage of disease were clearly recognizable. As the activity of the process increased, the enzyme activity
reduced in lymphocyte lysate and rose in blood plasma.
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