Clinical and diagnostic significance of evaluationof enzyme activity of purine metabolism adenyl branchin rheumatoid arthritis
- Authors: Zborovskiy AB1, Ushakova IS1, Zborovsky AB1, Uchakova IS1
-
Affiliations:
- Issue: Vol 4, No 3 (2007)
- Pages: 53-58
- Section: Articles
- URL: https://journals.eco-vector.com/1994-9480/article/view/140052
- ID: 140052
Cite item
Full Text
Abstract
The activity of adenosine deaminase (ADA), adenine deaminase (AD) and AMP-deaminase (AMPDA) in lymphocyte and erythrocyte lysates of peripheral blood was studied in 77 patients with rheumatoid arthritis (RA) upon
admission it hospital, after 10-12 days of treatment and on completion of inpatient care course.
While the AMPDA and AD activity was increased in erythrocyte lysates in patients with RA upon admission to hospital, the ADA, AD activity was reduced in lymphocytes, with AMPDA activity increased.
The enzymatic studies made it possible to diagnose the activity of the pathological process and the efficiency
of a complex treatment of the patients with RA.
admission it hospital, after 10-12 days of treatment and on completion of inpatient care course.
While the AMPDA and AD activity was increased in erythrocyte lysates in patients with RA upon admission to hospital, the ADA, AD activity was reduced in lymphocytes, with AMPDA activity increased.
The enzymatic studies made it possible to diagnose the activity of the pathological process and the efficiency
of a complex treatment of the patients with RA.
References
- Девятаева Н.М. Клинико-диагностическое значение исследования активности 5'-нуклеотидазы, АМФ-дезаминазы, адениндезаминазы, аденозиндезаминазы в лизатах лимфоцитов, эритроцитов и плазме крови больных системной красной волчанкой: дис. … канд. мед. наук. Волгоград, 2005. 226 с.
- Карпищенко А.Н. Медицинские лабораторные технологии: Справочник. СПб.: Интермедика, 2002. 600 с.
- Эрдес Ш.Ф., Фоломеева О.М. // Рус. мед. журн. 2004. Т. 12, № 20 (220). С. 1121-1122.
Supplementary files
