Diagnostic and prognostic value of platelet adhesiveness, microcirculation and lipid peroxidation abnormalitiesin coronary heart disease
- Authors: Gal'chenko OE1, Babaeva AR1, Galchenko OE1, Babaeva AR1
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Affiliations:
- Issue: Vol 4, No 4 (2007)
- Pages: 53-56
- Section: Articles
- URL: https://journals.eco-vector.com/1994-9480/article/view/140068
- ID: 140068
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Abstract
Platelet adhesion, microcirculation and lipid peroxidation reaction were assessed in patients with different
clinical forms of coronary heart disease (CHD). Platelet adhesion and blood viscosity were elevated in all forms of the
disease. Rheological abnormalities were associated with increased lipid peroxidation activity and decreased superoxide
dismutase activity. A close correlation between laboratory and clinical data was revealed. The degree of laboratory abnormalities
depended on severity of CHD. On the basis of the data obtained a mathematical model for prognostic purposes
was suggested.
clinical forms of coronary heart disease (CHD). Platelet adhesion and blood viscosity were elevated in all forms of the
disease. Rheological abnormalities were associated with increased lipid peroxidation activity and decreased superoxide
dismutase activity. A close correlation between laboratory and clinical data was revealed. The degree of laboratory abnormalities
depended on severity of CHD. On the basis of the data obtained a mathematical model for prognostic purposes
was suggested.
References
- Ольбинская Л.И., Кочкарева Ю.Б., Колосова К.Ю. // Сердечная недостаточность. 2004. Т. 5, № 3 (25). С. 127-130.
- Панченко Е.П. // Сердце. 2002. Т. 1, № 1 (1). С. 24-29.
- Петрищев Н.Н., Власов Т.Д. Эндотелий, адгезия и агрегация тромбоцитов: Дисфункция эндотелия / Под ред. Н.Н. Петрищева. СПб., 2003. С. 22-24.
- Сидоренко Б.А., Затейщиков Д.А., Баринов В.Г. и др. // Кремл. медицина. 2001. № 4. С. 16-18.
- Ситникова М.Ю., Иванов С.Г., Шляхто Е.В. // Сердечная недостаточность. 2006. Т. 7, № 4. С. 188-191.
- Guzk P., Burduk P., Bronisz M., et al. // Eur. Heart J. 2000. № 21 (Suppl). Р. 112.
- Yasunori Shintani, Hiroshi Ito, Katsuomi Iwakura, et al. // Amer.J. Cardiol. 2004. Vol. 93. Р. 974-978.