OXYGEN-REALTED BIOCIDITY OF NEUTROPHILS IN RATSWITH PARODONTAL INFLAMMATION IN HYPOTHYROIDISM
- Authors: Vokhmintseva LV1, Rymar SS1
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Affiliations:
- Issue: Vol 6, No 3 (2009)
- Pages: 63-66
- Section: Articles
- URL: https://journals.eco-vector.com/1994-9480/article/view/140266
- ID: 140266
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Abstract
To study the effect of experimental hypothyroidism on oxygen-related neutrophils biocidity in a rat model of acute
gingival trauma we investigated the spontaneous and stimulated nitroblue tetrazolium test. Hypothyroid state in rat was induced by administration of 25 mg/kg mercazolyl for 21 days. Inflammation in rats with acute gingival trauma and hypothyroidism leads to a reduction in spontaneous and stimulated nitroblue tetrazolium test, diminished levels of malondialdehyde and glutathione in gingival tissue, a decrease in serum malondialdehyde level and in hemolysate
glutathione level.
gingival trauma we investigated the spontaneous and stimulated nitroblue tetrazolium test. Hypothyroid state in rat was induced by administration of 25 mg/kg mercazolyl for 21 days. Inflammation in rats with acute gingival trauma and hypothyroidism leads to a reduction in spontaneous and stimulated nitroblue tetrazolium test, diminished levels of malondialdehyde and glutathione in gingival tissue, a decrease in serum malondialdehyde level and in hemolysate
glutathione level.
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