Acute phase proteins lactoferrin and ceruloplasminin ulcer disease of stomach and duodenum
- Authors: Vorob'eva AA1, Demidov AA1, Vorobуeva AA1, Demidov AA1
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- Issue: Vol 4, No 3 (2007)
- Pages: 62-65
- Section: Articles
- URL: https://journals.eco-vector.com/1994-9480/article/view/140077
- ID: 140077
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Abstract
The clinical and pathogenical significance of lactoferrin (Lf) and ceruloplasmin (CP) in gastric and duodenal
ulcer disease was evaluated. In acute phase of ulcer disease the level of Lf and CP was elevated 2- fold and 2,8- fold
accordingly while in remission it was normal. There were no correlation between clinical manifestations and Lf and CP level. In helicobacter-positive patients the level of Lf and CP was higher than in helicobacter-negative patients. These
findinsg suggest that the increase of Lf and CP in acute phase of ulcer disease was pathogenically beneficial and led to improved reparation of ulcer defect and increased antimicrobial resistance.
ulcer disease was evaluated. In acute phase of ulcer disease the level of Lf and CP was elevated 2- fold and 2,8- fold
accordingly while in remission it was normal. There were no correlation between clinical manifestations and Lf and CP level. In helicobacter-positive patients the level of Lf and CP was higher than in helicobacter-negative patients. These
findinsg suggest that the increase of Lf and CP in acute phase of ulcer disease was pathogenically beneficial and led to improved reparation of ulcer defect and increased antimicrobial resistance.
References
- Данилов А.В., Федулова И.В., Рязанцева Е.В. и др. // Тез. III съезда ревматологов России. Рязань, 2001. С. 33.
- Ким Л.Б., Калмыкова Е.Ю. // Клин. лаб. диагностика. 2006. № 5. С. 13-18.
- Коновалов А.П. // Врач. дело. 1988. № 9. С. 71-72.
- Марри Р., Греннер Д., Мейес П. и др. Биохимия человека. М.: Мир, 1993. 251 с.
- Мирошников В.М. Восстановительные реакции организма и стадиоспецифические антигены. Саратов, 1992. 156 с.
- Назаров П.Г., Полевщиков А.В. // Белки - маркеры патологических состояний: матер. 2-й школы-семинара и научной конференции молодых ученых с международным участием. Астрахань; Москва. 2001. С. 44-50.
- Шевченко О.П., Орлова О.В. // Клин. лаб. диагностика. 2006. № 7. С. 23-33.
- Яковлев А.М., Туркин В.В., Толмазова Т.В. // ЖМЭИ. 1988. № 10. С. 75-78.
- Bistrian B.R. Acute phase proteins and the systemic inflammatory response. // Crit. Care Med. 1999. № 27 (3). P. 452-453.
- Goldblum S.E., Cohen D.F., Jay M., et al. // Am. J. Physiol. 1997. № 252 (10). P. 27-32.
- Kataranovski M., Magic Z., Pejnovic N. // Physiol. Res. 1999. № 48 (6). P. 473-482.
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