ТHE PSYCHOPHARMACOLOGIC PROPERTIES OF THE DERIVATIVESOF GAMMA-AMINOBUTYRIC ACID (GABA) WITH THE HETEROCYCLIC SUBSTITUTEIN THE β-POSITION
- 作者: Tyurenkov IN1, Merkushenkova OV1, Bagmetova VV1, Tyurenkov IN1, Merkuschenkova OV1, Bagmetova VV1
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隶属关系:
- 期: 卷 5, 编号 4 (2008)
- 页面: 83-86
- 栏目: Articles
- URL: https://journals.eco-vector.com/1994-9480/article/view/118025
- ID: 118025
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There was carried out a study of the psychopharmacologic properties of the derivatives of gamma-aminobutyric acid with
the heterocyclic substitute in the в-position - the compounds with the laboratorial cipher РГПУ-136 and РГПУ-160. It was ascertained that the compound РГПУ-136 possesses nootropic activity and increases exercise performance; РГПУ-160 shows
distinct anxiolytic action comparable the preparation of positive control diazepam in intensity, reduces exercise performance as well as muscular tonus and muscle strength of the animals.
the heterocyclic substitute in the в-position - the compounds with the laboratorial cipher РГПУ-136 and РГПУ-160. It was ascertained that the compound РГПУ-136 possesses nootropic activity and increases exercise performance; РГПУ-160 shows
distinct anxiolytic action comparable the preparation of positive control diazepam in intensity, reduces exercise performance as well as muscular tonus and muscle strength of the animals.
参考
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