Cough in women
- Authors: Klyachkina I.L.1
-
Affiliations:
- Russian Medical Academy of Continuous Professional Education
- Issue: Vol 26, No 5 (2019)
- Pages: 127-132
- Section: Articles
- URL: https://journals.eco-vector.com/2073-4034/article/view/297673
- DOI: https://doi.org/10.18565/pharmateca.2019.5.127-132
- ID: 297673
Cite item
Open Access
Access granted
Abstract
A description of the pathogenesis of chronic cough (CC) in women is presented. Gender and age differences in the prevalence of CC and the sensitivity of the cough receptors are shown. The role of the female sex hormones and their effect on the cough receptors in the pathogenesis of CC is formulated. Based on the data obtained, the pathogenetic concept of CC as an independent disease is defined. Considering the difficulties of using antitussive drugs with their limited focus on either central mechanisms or peripheral receptors, such drug as Rengalin is considered, which combines antitussive, anti-inflammatory and bronchodilatory actions with the possibility of effective treatment of any type of cough in acute and chronic infectious and inflammatory allergic diseases.
Full Text
About the authors
Irina L. Klyachkina
Russian Medical Academy of Continuous Professional Education
Email: formozailk2012@yandex.ru
PhD, Associate Professor at the Department of Pulmonology
References
- Morice A.H., Jakes A.D., Faruqi S., et al. A worldwide survey of chronic cough: a manifestation of enhanced somatosensory response. Eur Respir J. 2014;44:1149-45. doi: 10.1183/09031936.0021781.
- Irwin R.S., French C.L., Chang A.B., et al. Classification of cough as a symptom in adults and management algorithms. Chest guideline and expert panel report. Chest. 2018;153(1):196-209.
- Song W.J., Chang Y.S., Faruqi S., et al. The global epidemiology of chronic cough in adults: a systematic review and meta-analysis. Eur Respir J. 2015;45(5):1479-81. doi: 10.1183/09031936.00218714.
- Irwin R.S, Boulet L.P, Cloutier M.M., et al. Managing cough as a defense mechanism and as a symptom: a consensus panel report of the American College of Chest Physicians. Chest. 1998;114:133-81.
- Morice A.H., Jakes A.D., Faruqi S., et al. A worldwide survey of chronic cough: a manifestation of enhanced somatosensory response. Eur Respir J. 2014;44:1149-55. Doi:10.1183 / 09031936.00217813.
- Escamilla R., Roche N. Cough hypersensitivity syndrome: towards a new approach to chronic cough. Eur Respir J. 2014;44:1103-106.
- Pavord I.D., Chung K.F Management of chronic cough. Lancet. 2008;371:1375-84.
- Brooks S.M. Perspective on the human cough refex. Cough. 2011;7:10. doi: 10.1186/1745-9974-7-10.
- Ramya R.S., Jayanthi N., Alexander PC., et al. Gastroesophageal refux disease in pregnancy: a longitudinal study. Trop Gastroenterol. 2014;35:168-72.
- Dicpinigaitis PV., Rauf K. The influence of gender on cough reflex sensitivity. Chest. 1998;113(5):1319-21.
- Gibson G.R. Enalapril-induced cough. Arch Intern Med. 1989;149:2701-703.
- Fujimura M., Sakamoto S., Kamio Y, Matsuda T. Sex difference in the inhaled tartaric acid cough threshold in non-atopic healthy subjects. Thorax. 1990;45:633-33.
- Fujimura M., Sakamoto S., Matsuda T. Bronchodilator-resistive cough in atopic patients: bronchial reversibility and hyper responsiveness. Intern Med. 1992;31:447-52.
- Fujimura M., Kasahara K., Yasui M., et al. Atopy in cough sensitivity to capsaicin and bronchial responsiveness in young females. Eur Respir J. 1998;11:1060-63.
- Varechova S., Plevkova J., Hanacek J., Tatar M. Role of gender and pubertal stage on cough sensitivity in childhood and adolescence. J Physiol Pharmacol. 2008;59(Suppl. 6):719-26.
- Boileau S., Deschildre A. Acute respiratory distress in the newborn and the child. Foreign bodies of the upper respiratory tract. Rev Prat. 2010;60:715-20.
- Thach B.T. Maturation of cough and other refexes that protect the fetal and neonatal airway Pulm Pharmacol Ther. 2007;20:365-70.
- Undem B.J., Carr M.J., Kollarik M. Physiology and plasticity of putative cough fbers in the guinea pig. Pulm Pharmacol Ther. 2002;15:193-98.
- Li J.S, Peat J.K., Xuan W., Berry G. Meta-analysis on the association between environmental tobacco smoke (ETS) exposure and the prevalence of lower respiratory tract infection in early childhood. Pediatr Pulmonol. 1999;27:5-13.
- Carskadon M.A., Acebo C. A self-administered rating scale for pubertal development. J Adolescent Health. 1993;14:190-95.
- Peng H.Y., Huang PC., Liao J.M., et al. Estrous cycle variation of TRPV1-mediated crossorgan sensitization between uterus and NMDAdependent pelvic-urethra refex activity. Am J Physiol Endocrinol Metab. 2008;295:559-68.
- Brugman S. The many faces of vocal cord dysfunction. What 36 years of literature tell us. Am J Respir Crit Care Med. 2003;167:A588.
- Amir O., Biron-Shental T. The impact of hormonal fuctuation on female vocal folds. Curr Opin Otolaryngol. Head Neck Surg. 2004;3:180-84.
- Morris M.J., Allan PF., Perkins PJ. Vocal cord dysfunction: etiologies and treatment. Clin Pulm Med. 2006;13:73-86.
- Gibson P.G., Vertigan A.E. Speech pathology for chronic cough: a new approach. Pulm Pharmacol Ther. 2009;22:159-62.
- Ryan N.M., Vertigan A.E., Gibson PG. Chronic cough and laryngeal dysfunction improve with specific treatment of cough and paradoxical vocal fold movement. Cough. 2009;5:4. doi: 10.1186/1745-9974-5-4.
- Niimi A., Torrego A., Nicholson A.G., et al. Nature of airway inflammation and remodeling in chronic cough. J Allergy Clin Immunol. 2005; 116:566-56.
- McGarvey L., Heaney L., MacMahon J., Ennis M. Eosinophilic bronchitis is an important cause of chronic cough. Am J Respir Crit Care Med. 2000;151:1753-54.
- Zaitsu M., Narita S.I., Lambert K.C., et al. Estradiol activates mast cells via a non-genomic estrogen receptor-а and calcium infux. Mol Immunol. 2007;44:1977-85.
- Zierau O., Zenclussen A.C., Jensen F Role of female sex hormones, estradiol and progesterone, in mast cell behavior. Front Immunol. 2012;3:169. doi: 10.3389/fmmu. 2012.00169.
Supplementary files
