OUTCOMES OF DYSMETABOLIC NEPHROPATHIES: RESULTS OF THE RETROSPECTIVE STUDY
- Authors: Maksudova Adelya Nailevna -1, Salikhov Il'dar Gazimdzhanovich -1, Mal'tsev Stanislav Viktorovich -1
-
Affiliations:
- Issue: No 5 (2011)
- Pages: 51-53
- Section: Articles
- URL: https://journals.eco-vector.com/2075-3594/article/view/246018
- ID: 246018
Cite item
Full Text
Abstract
Aim. Assessment of long-term outcomes of dysmetabolic nephropathy.
Methods. 40 patients (14 male, 26 female, age 16 - 28 years) with dysmetabolic nephropathy in childhood were included into the study. 30 healthy volunteers served as controls. In all patients parameters, characterizing renal function, were determined.
Results. 2 patients demonstrated isolated crystaluria, 21 - signs of dysmetabolic nephropathy, 10 had tubulo-interstitial nephritis, 7 - isolated changes in urinalysis. In comparison with healthy controls, group of patients, who had dysmetabolic nephropathy in childhood, shown decreased tubular water reabsorbtion, elevated uric acid clearance, fractional excretion of uric acid and calcium, and raised urinary concentration of oxalic acid.
Conclusion. Long-term outcomes of dysmetabolic nephropathy are variable and may be considered for long monitoring of signs of chronic kidney disease in this patients.
Methods. 40 patients (14 male, 26 female, age 16 - 28 years) with dysmetabolic nephropathy in childhood were included into the study. 30 healthy volunteers served as controls. In all patients parameters, characterizing renal function, were determined.
Results. 2 patients demonstrated isolated crystaluria, 21 - signs of dysmetabolic nephropathy, 10 had tubulo-interstitial nephritis, 7 - isolated changes in urinalysis. In comparison with healthy controls, group of patients, who had dysmetabolic nephropathy in childhood, shown decreased tubular water reabsorbtion, elevated uric acid clearance, fractional excretion of uric acid and calcium, and raised urinary concentration of oxalic acid.
Conclusion. Long-term outcomes of dysmetabolic nephropathy are variable and may be considered for long monitoring of signs of chronic kidney disease in this patients.
About the authors
- Maksudova Adelya Nailevna
- Salikhov Il'dar Gazimdzhanovich
- Mal'tsev Stanislav Viktorovich
References
- Мальцев С.В. Физиология и патология минерального обмена у детей, Каз. мед. журнал, 1997; 5: 3-11
- Мальцев С.В., Давыдова В.М., Землякова Э.И. Клиника и диагностика обменных нефропатий у детей. Каз.мед.журнал 1986; 5: 358-360.
- Багдасарова И.В., Стоева Т.В., Желтовская Н.И. Изучение клинико-лабораторных особенностей при дисметаболических нефропатиях у детей. Перинатология и педиатрия 2009; 3: 71-73.
- Малкоч А.В., Гаврилова В.А Дисметаболические нефропатии у детей. Леч врач 2001; 6:32-36.
- Воронина Н.В. Оксалатно-кальциевая нефропатия у взрослых. Тер. арх. 2007; 6: 82-85.
- Rastegar А, Kasgarian М..The clinical spectrum of tubulointerstitial nephritis. Kidney Int 1998; 54:313-327
Supplementary files
