Vol 4, No 1 (2016)

The article describes the possible side responses on cosmetic procedures. There is a review of pharmaceutical and cosmeceutical agents for external use to treat and prevent the complications. We have described the reason - ability of the external dosage forms use of antihistaminic action.

The microscopical diagnostic elements of powdered raw materials in the tablets «GINK- GOTROPIL» were studied. It was concluded that the tablets «GINKGOTROPIL» contain the leaves of Ginkgo biloba L. and the herbs of a Filipendula ulmaria (L.) Maxim. Diagnosis of anatomic signs of plant components allows for the standardization of the drug in terms of«Microscopy».

Chromatographic researches conducted have allowed determination of the flavonoids presence in raw materials of Salvia farinacea Benth. They were rutin, quercetin, hyperoside, and 5 phenol carbonic acids: caffeic, p-coumaric, ferulic, gallic, and cinnamic acids. The quantitative content of the sum of flavonoids in Salvia farinacea Benth. was conducted by the method of differential spectrophotometry, and it amounted to 0.55-0.60% in terms of rutin. The research conducted made it possible to expand the scientific data of phenolic compounds of Salvia farinacea Benth. and to offer the possibility of recycling, monitoring procurement and targeted use of Salvia farinacea Benth. herb in pharmacy and medicine.

Distillers grains are a huge secondary raw material resource, prospective for different fields, including pharmaceutical use, because of a rich content of biologically active com- pounds. The purpose of this paper was to esti- mate possibilities of the pharmaceutical use of distillers grains as the additive agent by means of surface-active properties of distillers grains study as well as pectins, isolated from them. We have established the surface-active properties of the liquid phase of the distillers wheat grains by means of higher pressure of air bubbles with the use of Rehbinder’s apparatus. It contained 6.67 mol/m3 pectins, and pectins isolated from a solid phase of the same distillers grains: sur- face activity 11.67 and 7.54, saturated surface excess amounted to 1.28×10-5 and 6.25×10-5 mol/m2, critical concentration of micelle forma- tion amounted to 1.32 mol/m3 and 1.48 mol/m3 respectively. Surface-active characteristics of distillers grains and isolated pectins are compa- rable with well-known natural polysaccharides (sodium alginate, polygalacturonic acid, beet bin pectin), which are used as additive agents in technology of medicinal plants. We have de- termined the sizes of pectins molecules from distillers grains in the unsaturated adsorption layers, which differed from the well-known polysaccharides by lesser square (2.658 Å2), radius (0.920 Å), diameter of cross-section (1.840 Å) and the volume (2727 Å3) at the bigger mass per surface unit (1.031×10-4 кг) and a length (1026 Å). The data obtained by the sizes of pectin molecules are the favorable factor, which conduced their high biological availability.

Various interactive teaching methods and techniques are extensively used in modern higher schools. Their implementation is considered to be one of the most significant and efficient ways to improve quality of pharmaceutical professional training. Efficiency of these interactive techniques applied at the Department of Economics and Management of Pharmaceutical Business of Smolensk State Medical University has been comprehensively investigated and assessed. Obtained results are presented in the paper, as well as students’ survey data as consumers of educational services. Fifth year full-time students were involved into the study. Students’ awareness on potentials and significance of applied interactive teaching methods, as well as their interest in innovative forms to gain professional knowledge comprised 93.3%. Potentials of interactive techniques to teach students to deal with a diversity of real life practical professional tasks and problems are particularly emphasized in the study (86.7% students).