Correction of complications in patients with invasive bladder cancer after the combination therapy



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Abstract

Among the urinary organs neoplasms, bladder tumors are on the first place and account for 70% of all neoplasms. Increasing of lifetime in the developed countries and the worldwide tendency to ageing of the population, stipulates the malignant neoplasms morbidity. Despite the modern opportunity of early detection of bladder cancer (8C), in Russia only 70% cases are non-invasive tumors and 30% cases are muscular invasion. Approximately V, of patients with the II stage of disease have distant metastasis at the moment of establishing diagnosis. Transurethral resection (TUR) as a medical diagnostic procedure is of much importance and it is added by biopsy of tumor base including muscular tissue of ВС. BC division on the basis of muscular invasion degree has principal significance as treatment variants radically differ. The standard treatment of invasive BC is radical cystectomy with lymphadenectomy. This way of treatment is usual for patients with invasive BC without distant metastasis and involvement of regional lymphagland that is the stage T2-T36NOMO. 5-year survival rate of patients with invasive BC who were performed with radical cystectomy with lymphadenectomy, amounted to 58%. However, as a result of combination therapy usage including TUR with the follow-up radiochemotherapy, only 60-80% of patients were observed to have full tumor regression according to the data of several authors. It can be correlated to the application of radical cystectomy, but at the same time possible correction variants of complications after these different treatment methods are not investigated till the end.

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About the authors

A D Kaprin

FSI Russian Scientific Rentgenradiology Centre, Moscow

N Yu Dobrovolskaya

FSI Russian Scientific Rentgenradiology Centre, Moscow

A Vladimirovich Shestakov

FSI Russian Scientific Rentgenradiology Centre, Moscow

Email: alexast@inbox.ru

M Kh Shaipov

FSI Russian Scientific Rentgenradiology Centre, Moscow

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Copyright (c) 2011 Kaprin A.D., Dobrovolskaya N.Y., Shestakov A.V., Shaipov M.K.

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