GENOME POLYMORPHISM STREPTOCOCCUS DYSGALACTIAE SUBSPECIES EQUISIMILIS



Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

Streptococcus dysgalactiae subspecies equisimilis is the most wide-spread representative of group G streptococci and an essential aetiologic agent of most human deseases. Despite of the published genome-wide sequence of S. dysgalactiae subsp. equisimilis, there are almost no data on the genetic heterogeneity of this subspecies provided in the present-day literature. This document provides for the comparative analysis of a vast collection of S. dysgalactiae subsp. equisimilis strains isolated in various geographic regions. Virulence genes scpG, lmb, nga, speG and ska have been analyzed for presence. High-grade heterogeneity of scpG gene has been detected. Some strains have been subjected to emm-genotyping. Strains have been analyzed through the pulsed-field electrophoresis. As a result, the significant genome polymorphism of S. dysgalactiae subsp. equisimilis was found out.

Full Text

Restricted Access

About the authors

Yu Yu Uliasov

Institute of Experimental Medicine NWB RAMS

Email: kolpino@hotmail.com
St.-Petersburg, Russia

A V Dmitriev

Institute of Experimental Medicine NWB RAMS

St.-Petersburg, Russia

References

  1. Broyles L. N., Van Beneden C., Beall B. et al. Populaion-based study of invasive disease due to P-hemolytic streptococci of groups other than A and B // Clin. Infect. Dis.- 2009.- Vol. 48.- P. 706-712.
  2. Facklam R. What happened to streptococci: overview of taxonomic and nomenclature changes // Clin. Microbiol. Rev.- 2002.- Vol. 15.-P. 613-630.
  3. Ruoff K. L., Whiley R. A., Beighton D. Streptococcus // Manual of clinical microbiology.- 2003.- P. 405-421.
  4. Lancefield R. C., Hare R. The serological differentiation of pathogenic and non-pathogenic streptococci from parturient woman // J. Exp. Med.- 1935.- Vol. 61.- P. 335 -349.
  5. Nohlgard C., Bjorklind A., Hammar H. Group G streptococcal infections on a dermatological ward // Acta Derm. Venereol.- 1992.- Vol. 72.- P. 128-130.
  6. Alberti 5., Garcia-Rey C., Garcia-Laorden M. I. et al. The Spanish surveillance group for respiratory pathogens: survey of emm-like gene sequences from pharyngeal isolates of group C and group G streptococci collected in Spain // J. Clin. Microbiol.- 2005.- Vol. 43.-P. 1433-1436.
  7. Reissmann S., Friedrichs C., Rajkumari R. et al. Contribution of Streptococcus anginosus to infections caused by groups C and G streptococci in Southern India // Emerg. Infect. Dis.- 2010.- Vol. 16.- P. 656-663.
  8. Barnham M. R. D., Weightman N. C., Anderson A. W., Tanna A. Streptococcal toxic shock syndrome: a description of 14 cases from North Yorkshire, UK // Clin. Microbiol. Infect.- 2002.- Vol. 8.- P. 174-181.
  9. Hashikawa S., Iinuma Y., Furushita M. et al. Characterization of group C and G streptococcal strains that cause streptococcal toxic shock syndrome // J. Clin. Microbiol.- 2004.- Vol. 42.- P. 186-192.
  10. Natoli S., Fimiani C., Faglieri N. et al. Toxic shock syndrome due to group C streptococci. A case report // Intensive Care Med.- 1996.-Vol. 22.- P. 985-989.
  11. Wagner J. G., Schlievert P. M., Assimacopoulos A. Р. et al. Acute group G streptococcal myositis associated with streptococcal toxic shock syndrome: case report and review // Clin. Infect. Dis.- 1996.- Vol. 23.- P. 1159-1161.
  12. Collins C. M., Kimura A, Bisno A. L. Group G streptococcal M protein exhibits structural features analogous to those of class I M protein of group A streptococci // Infect. Immun.- 1992.- Vol. 60.- P. 3689-3696.
  13. McDonald M., Towers R. J., Andrews R. M. et al. Epidemiology of Streptococcus dysgalactiae subsp. equisimilis in tropical communities, Northern Australia // Emerg. Infect. Dis.- 2007.- Vol. 13.- P. 1694-1700.
  14. Rato M. G., Nerlich A., Bergmann R. et al. Virulence gene pool detected in bovine group C Streptococcus dysgalactiae subsp. dysgalactiae isolates by use of a group A S. pyogenes virulence microarray // J. Clin. Microbiol.- 2011.- Vol. 49.- P. 2470-2479.
  15. Timmer A. M., Kristian S. A., Datta V. et al. Serum opacity factor promotes group A streptococcal epithelial cell invasion and virulence // Mol. Microbiol.- 2006.- Vol. 62.- P. 15-25.
  16. Ильясов Ю. Ю., Biswas I., Тотолян A. A., Дмитриев А. В. Метод дифференциальной диагностики стрептококков групп С и G // Клиническая лабораторная диагностика.- 2011.- № 2.- С. 40-43.
  17. Jensen A., Kilian M. Delineation of Streptococcus dysgalactiae, its subspecies, and its clinical and phylogenetic relationship to Streptococcus pyogenes // J. Clin. Microbiol.- 2012.- Vol. 50.- P. 113-126.
  18. Lefebure T., Richards V. P., Lang P. et al. Gene repertoire evolution of Streptococcus pyogenes inferred from phylogenomic analysis with Streptococcus canis and Streptococcus dysgalactiae // PLoS One.- 2012.- Vol. 7.- e37607.
  19. Дмитриев А. В., Hu Y. Y., Shen A. D. и др. Анализ клинических штаммов стрептококков группы В методами молекулярной генетики // Медицинский академический журнал.- 2002.- Т. 2, № 2.- С. 18-27.
  20. Dmitriev A. V., Shakleina E., Tkacikova L. et al. Genetic heterogeneity of the pathogenic potentials of human and bovine group B streptococci // Folia Microbiol.- 2002.- Vol. 47.- P. 291-295.
  21. Dmitriev A.V., Suvorov A. N., Shen A.D., Yang Y. H. Clinical diagnosis of group B streptococci by scpB gene based PCR // Indian. J. Med. Res.- 2004.- Vol. 119 (suppl.).- P. 233-236.
  22. Koroleva I. V., Efstratiou A., Suvorov A. N. Structural heterogeneity of the streptococcal C5a peptidase gene in Streptococcus pyogenes // J. Bacteriol.- 2002.- Vol. 184.- P. 6384-6386.
  23. Beall B., Facklam R., Thompson T. Sequencing emm-specific PCR products for routine and accurate typing of group A streptococci // J. Clin. Microbiol.- 1996.- Vol. 34.- P. 953-958.
  24. Sunaoshi K., Murayama S. Y., Adachi K. et al. Molecular emm genotyping and antibiotic susceptibility of Streptococcus dysgalactiae subsp. equisimilis isolated from invasive and non-invasive infections // J. Med. Microbiol.- 2010.- Vol. 59.- P. 82-88.
  25. Davies M. R., McMillan D. J., Van Domselaar G. H. et al. Phage 3396 from a Streptococcus dysgalactiae subsp. equisimilis pathovar may have its origins in Streptococcus pyogenes // J. Bacteriol- 2007.- Vol. 189.- P. 2646-2652.
  26. Beres S. B., Sylva G. L., Barbian K. D. et al. Genome sequence of a serotype M3 strain of group A Streptococcus: phage-encoded toxins, the high-virulence phenotype, and clone emergence // Proc. Natl. Acad. Sci. USA.- 2002.- Vol. 99.- P. 10078-10083.

Supplementary files

Supplementary Files
Action
1. JATS XML
Download

Copyright (c) 2012 Uliasov Y.Y., Dmitriev A.V.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ПИ № ФС 77 - 74760 от 29.12.2018 г.


This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies