GENOME POLYMORPHISM STREPTOCOCCUS DYSGALACTIAE SUBSPECIES EQUISIMILIS
- Authors: Uliasov Y.Y.1, Dmitriev AV1
-
Affiliations:
- Institute of Experimental Medicine NWB RAMS
- Issue: Vol 12, No 2 (2012)
- Pages: 90-96
- Section: Articles
- Published: 15.06.2012
- URL: https://journals.eco-vector.com/MAJ/article/view/9894
- DOI: https://doi.org/10.17816/MAJ12290-96
- ID: 9894
Cite item
Abstract
Streptococcus dysgalactiae subspecies equisimilis is the most wide-spread representative of group G streptococci and an essential aetiologic agent of most human deseases. Despite of the published genome-wide sequence of S. dysgalactiae subsp. equisimilis, there are almost no data on the genetic heterogeneity of this subspecies provided in the present-day literature. This document provides for the comparative analysis of a vast collection of S. dysgalactiae subsp. equisimilis strains isolated in various geographic regions. Virulence genes scpG, lmb, nga, speG and ska have been analyzed for presence. High-grade heterogeneity of scpG gene has been detected. Some strains have been subjected to emm-genotyping. Strains have been analyzed through the pulsed-field electrophoresis. As a result, the significant genome polymorphism of S. dysgalactiae subsp. equisimilis was found out.
Full Text
![Restricted Access](https://journals.eco-vector.com/lib/pkp/templates/images/icons/text_lock.png)
About the authors
Yu Yu Uliasov
Institute of Experimental Medicine NWB RAMS
Email: kolpino@hotmail.com
St.-Petersburg, Russia
A V Dmitriev
Institute of Experimental Medicine NWB RAMSSt.-Petersburg, Russia
References
- Broyles L. N., Van Beneden C., Beall B. et al. Populaion-based study of invasive disease due to P-hemolytic streptococci of groups other than A and B // Clin. Infect. Dis.- 2009.- Vol. 48.- P. 706-712.
- Facklam R. What happened to streptococci: overview of taxonomic and nomenclature changes // Clin. Microbiol. Rev.- 2002.- Vol. 15.-P. 613-630.
- Ruoff K. L., Whiley R. A., Beighton D. Streptococcus // Manual of clinical microbiology.- 2003.- P. 405-421.
- Lancefield R. C., Hare R. The serological differentiation of pathogenic and non-pathogenic streptococci from parturient woman // J. Exp. Med.- 1935.- Vol. 61.- P. 335 -349.
- Nohlgard C., Bjorklind A., Hammar H. Group G streptococcal infections on a dermatological ward // Acta Derm. Venereol.- 1992.- Vol. 72.- P. 128-130.
- Alberti 5., Garcia-Rey C., Garcia-Laorden M. I. et al. The Spanish surveillance group for respiratory pathogens: survey of emm-like gene sequences from pharyngeal isolates of group C and group G streptococci collected in Spain // J. Clin. Microbiol.- 2005.- Vol. 43.-P. 1433-1436.
- Reissmann S., Friedrichs C., Rajkumari R. et al. Contribution of Streptococcus anginosus to infections caused by groups C and G streptococci in Southern India // Emerg. Infect. Dis.- 2010.- Vol. 16.- P. 656-663.
- Barnham M. R. D., Weightman N. C., Anderson A. W., Tanna A. Streptococcal toxic shock syndrome: a description of 14 cases from North Yorkshire, UK // Clin. Microbiol. Infect.- 2002.- Vol. 8.- P. 174-181.
- Hashikawa S., Iinuma Y., Furushita M. et al. Characterization of group C and G streptococcal strains that cause streptococcal toxic shock syndrome // J. Clin. Microbiol.- 2004.- Vol. 42.- P. 186-192.
- Natoli S., Fimiani C., Faglieri N. et al. Toxic shock syndrome due to group C streptococci. A case report // Intensive Care Med.- 1996.-Vol. 22.- P. 985-989.
- Wagner J. G., Schlievert P. M., Assimacopoulos A. Р. et al. Acute group G streptococcal myositis associated with streptococcal toxic shock syndrome: case report and review // Clin. Infect. Dis.- 1996.- Vol. 23.- P. 1159-1161.
- Collins C. M., Kimura A, Bisno A. L. Group G streptococcal M protein exhibits structural features analogous to those of class I M protein of group A streptococci // Infect. Immun.- 1992.- Vol. 60.- P. 3689-3696.
- McDonald M., Towers R. J., Andrews R. M. et al. Epidemiology of Streptococcus dysgalactiae subsp. equisimilis in tropical communities, Northern Australia // Emerg. Infect. Dis.- 2007.- Vol. 13.- P. 1694-1700.
- Rato M. G., Nerlich A., Bergmann R. et al. Virulence gene pool detected in bovine group C Streptococcus dysgalactiae subsp. dysgalactiae isolates by use of a group A S. pyogenes virulence microarray // J. Clin. Microbiol.- 2011.- Vol. 49.- P. 2470-2479.
- Timmer A. M., Kristian S. A., Datta V. et al. Serum opacity factor promotes group A streptococcal epithelial cell invasion and virulence // Mol. Microbiol.- 2006.- Vol. 62.- P. 15-25.
- Ильясов Ю. Ю., Biswas I., Тотолян A. A., Дмитриев А. В. Метод дифференциальной диагностики стрептококков групп С и G // Клиническая лабораторная диагностика.- 2011.- № 2.- С. 40-43.
- Jensen A., Kilian M. Delineation of Streptococcus dysgalactiae, its subspecies, and its clinical and phylogenetic relationship to Streptococcus pyogenes // J. Clin. Microbiol.- 2012.- Vol. 50.- P. 113-126.
- Lefebure T., Richards V. P., Lang P. et al. Gene repertoire evolution of Streptococcus pyogenes inferred from phylogenomic analysis with Streptococcus canis and Streptococcus dysgalactiae // PLoS One.- 2012.- Vol. 7.- e37607.
- Дмитриев А. В., Hu Y. Y., Shen A. D. и др. Анализ клинических штаммов стрептококков группы В методами молекулярной генетики // Медицинский академический журнал.- 2002.- Т. 2, № 2.- С. 18-27.
- Dmitriev A. V., Shakleina E., Tkacikova L. et al. Genetic heterogeneity of the pathogenic potentials of human and bovine group B streptococci // Folia Microbiol.- 2002.- Vol. 47.- P. 291-295.
- Dmitriev A.V., Suvorov A. N., Shen A.D., Yang Y. H. Clinical diagnosis of group B streptococci by scpB gene based PCR // Indian. J. Med. Res.- 2004.- Vol. 119 (suppl.).- P. 233-236.
- Koroleva I. V., Efstratiou A., Suvorov A. N. Structural heterogeneity of the streptococcal C5a peptidase gene in Streptococcus pyogenes // J. Bacteriol.- 2002.- Vol. 184.- P. 6384-6386.
- Beall B., Facklam R., Thompson T. Sequencing emm-specific PCR products for routine and accurate typing of group A streptococci // J. Clin. Microbiol.- 1996.- Vol. 34.- P. 953-958.
- Sunaoshi K., Murayama S. Y., Adachi K. et al. Molecular emm genotyping and antibiotic susceptibility of Streptococcus dysgalactiae subsp. equisimilis isolated from invasive and non-invasive infections // J. Med. Microbiol.- 2010.- Vol. 59.- P. 82-88.
- Davies M. R., McMillan D. J., Van Domselaar G. H. et al. Phage 3396 from a Streptococcus dysgalactiae subsp. equisimilis pathovar may have its origins in Streptococcus pyogenes // J. Bacteriol- 2007.- Vol. 189.- P. 2646-2652.
- Beres S. B., Sylva G. L., Barbian K. D. et al. Genome sequence of a serotype M3 strain of group A Streptococcus: phage-encoded toxins, the high-virulence phenotype, and clone emergence // Proc. Natl. Acad. Sci. USA.- 2002.- Vol. 99.- P. 10078-10083.
Supplementary files
![](/img/style/loading.gif)