Интерлейкин-1 и когнитивные функции мозга



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Цитокины семейства ИЛ-1 (ИЛ-1α и β, ИЛ-1 р.а, ИЛ-18) играют ключевую роль в процессах нейроиммунных взаимодействий. Хорошо известна их роль в регуляции гомеостатических функций организма (температуры тела, активности ГГНС, мотивационных состояний), в индукции проявлений продромального синдрома и в патогенезе различных нервных заболеваний. Настоящий обзор посвящен наименее изученным аспектам нейробиологии цитокинов семейства ИЛ-1 их участию в регуляции когнитивных функций мозга. Опубликованные данные и собственные исследования авторов доказывают влияние ИЛ-1α, ИЛ-Iβ и ИЛ-18 на процессы обучения и памяти, а также вскрывают различный характер их действия в ЦНС в раннем и взрослом возрасте.

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О Е Зубарева

ГУ «Научно-исследовательский институт экспериментальной медицины СЗО РАМН»

Виктор Матвеевич Клименко

ГУ «Научно-исследовательский институт экспериментальной медицины СЗО РАМН»

Email: klimenko_victor@mail.ru

Список литературы

  1. Завьялов В.П. Структурно-функциональная классификация и эволюция цитокинов // Вестник РАМН. 1993. № 2. С. 8-10.
  2. Зубарева O.E., Клименко В.М. Влияние на становление поведения в раннем постнатальном онтогенезе // Физиол. журн. им. И.М. Сеченова. 2005. № 4. С. 374-384.
  3. Зубарева O.E., Ефремов О.М., Симбирцев A.C., Клименко В.М. Интерлейкин -1 и депрессивные состояния // Рос. физиол. журн. им. И.М. Сеченова. 2001. Т. 87. № 10. С. 1450-1456.
  4. Зубарева O.E., Симбирцев A.C., Клименко В.М. и др. Действие провоспалительных цитокинов в раннем постнатальном онтогенезе на формирование когнитивных функций мозга // Аллергол. и иммунол. 2009. Т. 10. №2. С. 178.
  5. Клименко В.М., Зубарева O.E., Краснова И.Н. Роль внутримозговых рецепторов интерлейкина-1 в модуляции гомеостатических реакций организма // Нейрохимия. 1995. Т. 12. №2. С. 16-22.
  6. Клименко В.М., Зубарева O.E. Нейробиология цитокинов, поведение и адаптивные реакции // Рос. физиол. журн. им. И.М. Сеченова. 1999. Т. 85. № 9. С.1244-1254.
  7. Клименко В.М., Зубарева O.E., Барабанова С.В. Действие интерлейкина-1 на локомоторную активность и пространственную ориентацию крыс // Журнал ВИД. 1997. Т. 4. С. 760-761.
  8. Клименко В.М. Зубарева O.E., Людыно В.И. Молекулярные механизмы формирования поведения больного // Труды Межведомственного научного совета по экспериментальной и прикладной физиологии «Интегративная деятельность мозга». М.: Медицина, 2001. Т. 9. С. 50-58.
  9. Клименко В.М. Цитокины и нейробиология поведения больного // Основы нейроэндокринологии / Под ред. В.Г. Шаляпиной и П.Д. Шабанова. СПб.: Элбн-СПб. 2005. С. 249-306.
  10. Кетлинский С.А., Симбирцев A.C. Цитокины. СПб.: Фолиант, 2008.
  11. Albasser М.М., Poirier G.L., Aggleton J.P. Qualitatively different modes of perirhinal-hippocampal engagement when rats explore novel vs. familiar objects as revealed by c-Fos imaging // Eur. J. Neurosci. 2010. Vol. 31. № I. P. 134-147.*"
  12. Alboni S., Cervia D., Ross B. et al. Mapping of the full length and the truncated interleukin-18 receptor alpha in the mouse brain //J. Neuroimmunol. 2009. Vol. 214. № 1-2. P. 43-54.
  13. Alboni S., Cervia D., Sugama S., Conti B. Interleukin 18 in the CNS // J. Neuroinflammation. 2010. № 7. P. 9.
  14. Alboni S., Cervia D., Ross B. et al. Mapping of the full length and the truncated interleukin-18 receptor alpha in the mouse brain // J. Neuroimmunol. 2009. Vol. 214. № 1-2. P. 43-54.
  15. Allan S.M., Tyrrell P.J., Rothwell N.J. lnterleukin-1 and neuronal injury // Nat. Rev. Immunol. 2005. Vol. 5. № 8. P. 629-640.
  16. Aly H., Khashaba M.T., El-Ayouty M. et al. IL-lbeta, IL-6 and TNF-alpha and outcomes of neonatal hypoxic ischemic encephalopathy // Brain Dev. 2006. Vol. 28. №3. P. 178-182.
  17. Anforth H.R., Bluthe R.M., Bristow A. et al. Biological activity and brain actions of recombinant rat interleukin-1 alpha and interleukin-1 beta // Eur. Cytokine Netw. 1998. Vol. 9. № 3. P. 279-288.
  18. Anisman H., Merali Z. Cytokines, stress, and depressive illness // Brain Behav. Immunol. 2002. Vol. 16. №5. P. 513-524.
  19. Avital A., Goshen I., Kamsler A. et al. Impaired interleukin-1 signaling is associated with deficits in hippocampal memory processes and neural plasticity // Hippocampus. 2003. Vol. 13. № 7. P. 826-834.
  20. Bai Y., Hart R.P. Cultured sympathetic neurons express functional interleukin-1 receptors // J. Neuroimmunol. 1998. Vol. 91. № 1-2. P. 43-54.
  21. Balasingam V., Tejada-Berges T., Wright E. et al. Reactive astrogliosis in the neonatal mouse brain and its modulation by cytokines // J. Neurosci. 1994. Vol. 14. № 2. P. 846-856.
  22. Ban E., Milon G., Prudhomme N. et al. Receptors for interleukin-1 (alpha and beta) in mouse brain: mapping and neuronal localization in hippocampus // Neuroscience. 1991. Vol. 43. № 1. P. 21-30.
  23. Ban E.M., Sarliève L.L., Haour F.G. Interleukin-1 binding sites on astrocytes // Neuroscience. 1993. Vol. 52. № 3. P. 725-733. ’
  24. Banks W.A., Kastin A.J., Ehrensing C.A. Blood-bome interleukin-1 alpha is transported across the endothelial blood-spinal cord barrier of mice /7 J. Physiol. 1994. Vol. 479. № 2. P. 257-264.
  25. Banks W.A., Ortiz L., Plotkin S.R., Kastin A.J. Human interleukin (1L) 1 alpha, murine IL-1 alpha and murine IL-1 beta are transported from blood to brain in the mouse by a shared saturable mechanism /7 J. Pharmacol. Exp. Ther. 1991. Vol. 259. № 3. P. 988-996.
  26. Banks W.A., Kastin A.J., Ehrensing С.A. Blood-borne interleukin-1 alpha is transported across the endothelial blood-spinal cord barrier of mice // Physiol. 1994. Vol. 479. № 2. P. 257-264.
  27. Banks W.A., Kastin A.J. Blood to brain transport of interleukin links the immune and central nervous systems // Life Sei. 1991. Vol. 48. №25. P. 117-121.
  28. Barrientos R.M., Sprunger D.B., Campeau S. et al. BDNF mRNA expression in rat hippocampus following contextual learning is blocked by intrahippocampal IL-1 beta administration // J. Neuroimmunol. 2004. Vol. 155. № 1-2. P. 119-126.
  29. Bellinger F.P., Madamba S., Siggins G.R. Interleukin 1 beta inhibits synaptic strength and long-term potentiation in the rat CA1 hippocampus // Brain Res. 1993. Vol. 628. № 1-2. P. 227-234.
  30. Benedito M.A., Camarini R. Rapid eye movement sleep deprivation induces an increase in acetylcholinesterase activity in discrete rat brain regions // Braz. J. Med. Biol. Res. 2001. Vol. 34. № 1. P. 103-109.
  31. Bilbo S.D., Newsum N.J., Sprunger D.B. et al. Differential effects of neonatal handling on early life infection-induced alterations in cognition in adulthood // Brain Behav. Immunol. 2007. Vol. 21. № 3. P. 332-342.
  32. Bilbo S.D., Schwarz J.M. Early-life programming of later-life brain and behavior: a critical role for the immune system /7 Front Behav. Neurosci. 2009. № 3. P. 14.
  33. Blasi F., Riccio M., Brogi A. et al. Constitutive expression of interleukin-1 beta (IL-lbeta) in rat oligodendrocytes // Biol. Chem. 1999. Vol. 380. № 2. P. 259-264.
  34. Bluthé R.M., Dantzer R., Kelley K.W. Interleukin-1 mediates behavioral but not metabolic effects of tumor necrosis factor alpha in mice // Eur. J. Pharmacol. 1991. Vol. 209. № 3. P. 281-283.
  35. Bluthé R.M., Michaud B., Kelley K.W., Dantzer R. Vagotomy attenuates behavioral effects of interleukin-1 injected peripherally but not centrally // Neuroreport. 1996. Vol. 7. №9. P. 1485-1488.
  36. Bluthe R.M., Sparber S., Dantzer R. Modulation of the behavioral effects of interleukin-1 in mice by nitric oxide ,7 Neuroreport. 1992. Vol. 3. № 2. P. 207-209.
  37. Boileau I., Dagher A., Leyton M. et al. Modeling sensitization to stimulants in humans: an [11C] raclopride/positron emission tomography study in healthy men //Arch. Gen. Psychiatry. 2006. Vol. 63. №12. P. 1386-1395.
  38. Boksa P. Effects of prenatal infection on brain development and behavior: A review of findings from animal models // Brain Behav. Immunol. 2010. (In press.)
  39. Boraschi D., Rambaldi A., Sica A. et al. Endothelial cells express the interleukin-1 receptor type I // Blood. 1991. Vol. 78. №5. P. 1262-1267.
  40. Braff D.L., Geyer M.A., Light G.A. et al. Impact of prepulse characteristics on the detection of sensorimotor gating deficits in schizophrenia // Schizophr. Res. 200L VoL49.№ 1-2. P. 171-178.
  41. Bret-Dibat J.L., Bluthé R.M., Kent S. et al. Lipopoly-saccharide and interleukin-1 depress food-motivated behavior in mice by a vagal-mediated mechanism // Brain Behav. Immunol. 1995. Vol. 9. № 3. P. 242-246.
  42. Bunzeck N., Düzel E. Absolute coding of stimulus novelty in the human substantia nigra/VTA // Neuron. 2006. Vol. 51. № 3. P. 369-379.
  43. Cacabelos R., Barquero M., Garcia P. et al. Cerebrospinal fluid interleukin-1 beta(IL-l beta) in Alzheimer's disease and neurological disorders // Methods Find. Exp. Clin. Pharmacol. 1991. Vol. 13. № 7. P. 455-458.
  44. Cai Z., Lin S., Pang Y., Rhodes P.G. Brain Injury Induced by Intracerebral Injection of interleukin-1 beta and tumor Necrosis Factor-alpha // Neonatal. Rat. Pediatric. Res. 2004. Vol. 56. № 3. P. 377-384.
  45. Chandramohan Y., Droste S.K., Reul J.M. Novelty stress induces phospho-acetylation of histone H3 in rat dentate gyrus granule neurons through coincident signalling via the N-methyl-D-aspartate receptor and the glucocorticoid receptor: relevance for c-fos induction // Neurochem. 2007. Vol. 101. № 3. P. 815-828.
  46. Clausen B.H., Lambertsen K.L., Babcock A.A. et al. Interleukin-1 beta and tumor necrosis factor-alpha are expressed by different subsets of microglia and macrophages after ischemic stroke in mice.7 J. of Neuroinflammation. 2008. Vol. 5. № 46.
  47. Cumiskey D., Pickering M., O'Connor J.J. Interleukin-18 mediated inhibition of LTP in the rat dentate gyrus is attenuated in the presence of mGIuR antagonists // Ncurosci. Lett. 2007. Vol. 412. № 3. P. 206-210.
  48. Cumiskey D., Curran B.P., Herron C.E., O’Connor J.J. A role for inflammatory mediators in the IL-18 mediated attenuation of LTP in the rat dentate gyrus // Neuropharmacology. 2007. Vol. 52. № 8. P. 1616-1623.
  49. Cunningham E.T. Jr., Wada E., Carter D.B. et al. Localization of interleukin-1 receptor messenger RNA in murine hippocampus//Endocrinology'. 1991. Vol. 128. № 5. P. 2666-2668.
  50. Cunningham E.T. Jr., Wada E., Carter D.B. et al. In situ histochemical localization of type 1 interleukin-1 receptor messenger RNA in the central nervous system, pituitary, and adrenal gland of the mouse // J. Neurosci. 1992. Vol. 12. №3. P. 1101-1114.
  51. Curran B.P., Murray H.J., O'Connor J.J. A role for c-Jun N-terminal kinase in the inhibition of long-term potentiation by interleukin-1 beta and long-term depression in the rat dentate gyrus in vitro // Neuroscience. 2003. Vol. 118. № 2. Р.~347-357.
  52. Dammann O., Leviton A. Maternal intrauterine infection, cytokines, and brain damage in the preterm newborn / Pediatr. Res. 1997. Vol. 42. № 1. P. 1-8.
  53. Dantzer R., Bluthé R.M., Layé S. et al. Cytokines and sickness behavior // Ann. N.-Y. Acad. Sei. 1998. № 840. P. 586-590.
  54. Dantzer R. Cytokine, sickness behavior, and depression // Immunol. Allergy Clin. North Am. 2009. Vol. 29. № 2. P. 247-264. "
  55. Dantzer R., Kelley K.W. Twenty years of research on cytokine-induced sickness behavior// Brain Behav. Immunol. 2007. Vol. 21. № 2. P. 153-160.
  56. Das S., Mishra M.K., Ghosh J., Basu A. Japanese Encephalitis Virus infection induces IL-18 and IL-lbeta in microglia and astrocytes: correlation with in vitro cytokine responsiveness of glial cells and subsequent neuronal death // Neuroimmunol. 2008. Vol. 195. № 1-2. P. 60-72.
  57. Debets R., Timans J.C., Churakowa T. et al. IL-18 receptors, their role in ligand binding and function: anti-IL-lRAcPL antibody, a potent antagonist of IL-18 // J. Immunol. 2000. Vol. 165. № 9. P. 4950-4956.
  58. Desson S.E., Ferguson A.V. Interleukin Ibeta modulates rat subfornical organ neurons as a result of activation of a non-selective cationic conductance // J. Physiol. 2003. № 550. P. 113-122.
  59. Dinarello C.A. Biologic basis for interleukin-1 in disease // Blood. 1996.Vol. 87. № 6. P. 2095-2147.
  60. Dinarello C.A., Wolff S.M. Molecular basis of fever in humans // Am. J. Med. 1982. Vol. 72. № 5. P. 799-819.
  61. Duff G.W., Durum S.K. The pyrogenic and mitogenic actions of interleukin-1 are related//Nature. 1983. Vol. 304. № 5925. P. 449-451.
  62. Dunn A.J., Chuluyan H.E. The role of cyclo-oxygen-ase and lipoxygenase in the interleukin-1-induced activation of the HPA axis: dependence on the route of injection // Life Sei. 1992. Vol. 51. № 3. P. 219-225.
  63. Dunn A.J. Endotoxin-induced activation of cerebral catecholamine and serotonin metabolism: comparison with interleukin-1 // J. Pharmacol. Exp. Ther. 1992. Vol. 261. №3. P. 964-969.
  64. Dunn A.J. Nitric oxide synthase inhibitors prevent the cerebral tryptophan and serotonergic responses to endotoxin and interleukin-1 // Neurosci. Res. Commun. 1993. № 13. P. 149-156.
  65. Dunn A.J. Effects of cytokines and infections on brain neurochemistry//Clin. Neurosci. Res. 2006. Vol. 6. № 1-2. P. 52-68.
  66. Ericsson A., Liu C., Hart R.P., Sawchenko P.E. Type 1 interleukin-1 receptor in the rat brain: distribution, regulation, and relationship to sites of IL-1-induced cellular activation // J. Comp. Neurol. 1995. Vol. 361. №4. P. 681-698.
  67. Fatemi S.H. Potential microbial origins of schizophrenia and their treatments // Drugs Today (Bare.). 2009. Vol. 45. №4. P. 305-318.
  68. Feleder C., Tseng K.Y., Calhoon G.G., O’Donnell P. Neonatal intrahippocampal immune challenge alters dopamine modulation of prefrontal cortical interneurons in adult rats // Biol. Psychiatry. 2010. Vol. 67. № 4. P. 386-392.
  69. French R.A., VanHoy R.W., Chizzonite R. et al. Expression and localization of p80 and p68 interleukin-1 receptor proteins in the brain of adult mice 7 J. Neuroimmunol. 1999. Vol. 93. № 1-2. P. 194-202.
  70. Friedman Е.М., Reyes Т.М., Сое С.L. Context-dependent behavioral effects of interleukin-1 in the rhesus monkey (Macaca mulattaj.7 Psychoncuroendocrinology. 1996. Vol. 21. № 5. P. 455-468.
  71. Gabellec M.M., Crumcyrolle-Arias M., Le Saux F. et al. Expression of interleukin-1 genes and interleukin-1 receptors in the mouse brain after hippocampal injury // Neurosci. Res. 1999. Vol. 33. № 4. P. 251-260.
  72. Gibertini M. Cytokines and cognitive behavior // Neuroimmunomodulation. 1998. Vol. 5. № 3-4. P. 160-165.
  73. Gibertini M., Newton C., Friedman H., Klein T.W. Spatial learning impairment in mice infected with Legionella pneumophila or administered exogenous interleukin-1-beta // Brain Behav. Immunol. 1995. Vol. 9. № 2. P. 113-128.
  74. Giulian D., Young D.G., Woodward J. et al. Interleukin-1 is an astroglial growth factor in the developing brain // Neurosci. 1988. Vol. 8. № 2. P. 709-714.
  75. Giulian D., Baker T.J., Shin L.C., Lachman L.B. Interleukin 1 of the central nervous system is produced by ameboid microglia // J. Exp. Med. 1986. Vol. 164. № 2. P. 594-604.
  76. Giulian D., Lachman L.B. Interleukin-1 stimulation of astroglial proliferation after brain injury // Science. 1985. Vol. 228. № 4698. P. 497-499.
  77. Goshen I., Kreisel T., Ounailah-Saad H. et al. A dual role for interleukin-1 in hippocampal-dependent memory processes // Psychoneuroendocrinology. 2007. Vol. 32. №8-10. P. 1106-1115.
  78. Gutierrez E.G., Banks W.A., Kastin A.J. Blood-borne interleukin-1 receptor antagonist crosses the blood-brain barrier // J. Neuroimmunol. 1994. Vol. 55. № 2. P. 153-160.
  79. Gwosdow A.R., O'Connell N.A., Abou-Samra A.B. Interleukin-1 increases protein kinase A activity by a cAMP-independent mechanism in AtT-20 cells // Am. J. Physiol. 1994. Vol. 266. № 1. Pt. 1. P. E79-84.
  80. Hansen M.K., Taishi P., Chen Z., Krueger J.M. Vagotomy Blocks the Induction of Interleukin-lβ (IL-Iβ) mRNA in the Brain of Rats in Response to Systemic IL-lβ // J. Neuroscience. 1998. Vol. 18. № 6. P. 2247-2253.
  81. Hart R.P., Liu C., Shadiack A.M. et al. An mRNA homologous to interleukin-1 receptor type I is expressed in cultured rat sympathetic ganglia // J. Neuroimmunol. 1993. Vol. 44. № 1. P. 49-56.
  82. Hedtjäm M., Mallard C., Arvidsson P., Hagberg H. White matter injury' in the immature brain: role of in-terlcukin-18 // Neurosci. Lett. 2005. Vol. 373. № I. P. 16-20.
  83. Hein A.M., Stutzman D.L., Bland S.T. et al. Prostaglandins are necessary and sufficient to induce contextual fear learning impairments after interleukin-1 beta injections into the dorsal hippocampus // Neuroscience. 2007. Vol. 150. № 4. P. 754-763.
  84. Hong H.J., Shin D.W., Lee E.H. et al. Hypothalamic-pituitary-adrenal reactivity in boys with attention deficit hyperactivity disorder// Yonsei Med. J. 2003. Vol. 44. №4. P. 608-614.
  85. Hu B., Wang S., Zhang Y. el al. A nuclear target for interleukin-1 alpha: interaction with the growth suppressor nccdin modulates proliferation and collagen expression '/ Proe. Natl. Acad. Sei. USA. 2003. Vol. 100. № 17. P. 10008-10013.
  86. Hunsaker M.R., Rosenberg J.S., Kesner R.P. The role of the dentate gyrus, CA3a, b, and CA3c for detecting spatial and environmental novelty ii Hippocampus. 2008. Vol. 18. № 10. P. 1064-1073.
  87. Ilyin S.E., Gayle D., González-Gómez I. et al. Brain tumor development in rats is associated with changes in central nervous system cytokine and neuropeptide systems // Brain Res. Bull. 1999. Vol. 48. № 4. P. 363-373.
  88. Imeri L., Opp M.R. How (and why) the immune system makes us sleep '/ Nat. Rev. Neurosci. 2009. Vol. 10. №3. P. 199-210.
  89. Jeon G.S., Park S.K., Park S.W. et al. Glial expression of interleukin-18 and its receptor after excitotoxic damage in the mouse hippocampus // Neurochem. Res. 2008. Vol. 33. № 1. P. 179-184.
  90. John G.R., Lee S.C., Song X. et al. IL-1-regulated responses in astrocytes: relevance to injury and recovery //Glia. 2005. Vol. 49. №2. P. 161-176.
  91. Juric D.M., Carman-Krzan M. Interleukin-1 beta, but not IL-1 alpha, mediates nerve growth factor secretion from rat astrocytes via type I IL-1 receptor 7 Int. J. Dev. Neurosci. 2001. Vol. 19. № 7. P. 675-683.
  92. Kabiersch A., Furukawa H., del Rey A., Besedovsky H.O. Administration of interleukin-1 at birth affects dopaminergic neurons in adult mice // Ann. N.-Y. Acad. Sei. 1998. № 840. P. 123-127.
  93. Kanno T., Nagata T., Yamamoto S. et al. Interleukin-18 stimulates synaptically released glutamate and enhances postsynaptic AM PA receptor responses in the CA1 region of mouse hippocampal slices /' Brain Res. 2004. Vol. 1012 № 1-2. P. 190-193.
  94. Katsuki H., Nakai S., Hirai Y. et al. Interleukin-1 beta inhibits long-term potentiation in the CA3 region of mouse hippocampal slices // Eur. J. Pharmacol. 1990. Vol. 181. № 3. P. 323-326.
  95. Kent S., Bluthe R.M., Dantzer R. et al. Different receptor mechanisms mediate the pyrogenic and behavioral effects of interleukin 1 // Proc. Natl. Acad. Sei. USA. 1992. Vol. 89. № 19. P. 9117-9120.
  96. Konsman J.P., Pamet P., Dantzer R. Cytokine-induced sickness behaviour: mechanisms and implications // Trends Neurosci. 2002. Vol. 25. № 3. P. 154-159.
  97. Krueger J.M., Walter J., Dinarello C.A. et al. Sleep-promoting effects of endogenous pyrogen (interleukin-1) //Am. J. Physiol. 1984. Vol. 246. № 6. Pt. 2. P. R994-999.
  98. Laflamme N., Lacroix S., Rivest S. An Essential Role of Interleukin-1 Beta in Mediating NF-КВ Activity and COX-2 Transcription in Cells of the Blood-Brain Barrier in Response to a Systemic and Localized Inflammation But Not During Endotoxemia // J. Neuroscience. 1999. Vol. 19. № 24. P. 10923-10930.
  99. Lagace D.C., Donovan М.H., DeCarolis N.A. et al. Adult hippocampal neurogenesis is functionally important for stress-induced social avoidance // Proc. Natl. Acad. Sei. USA. 2010. Vol. 107. № 9. P. 4436-4441.
  100. Lai A.Y., Swayze R.D., El-Husseini A., Song C. Interleukin-1 beta modulates AMPA receptor expression and phosphorylation in hippocampal neurons // J. Neuroimmunol. 2006. Vol. 175. № 1-2. P. 97-106.
  101. Lakhan S.E., Kirchgessner A., Hofer M. Inflammatory mechanisms in ischemic stroke: therapeutic approaches // J. Transi. Med. 2009. № 7. P. 97.
  102. Lee Y.B., Nagai A., Kim S.U. Cytokines, chemokines. and cytokine receptors in human microglia // J. Neurosci. Res. 2002. Vol. 69. № 1. P. 94-103.
  103. Leonard B. Stress, depression and the activation of the immune system // World J. Biol. Psychiatry. 2000. Vol. l.№ 1. P. 17-25.
  104. Ling Z., Gayle D.A., Ma S.Y. et al. In utero bacterial endotoxin exposure causes loss of tyrosine hydroxylase neurons in the postnatal rat midbrain // Mov. Disord. 2002. Vol. 17. № 1. P. 116-124.
  105. Luheshi N.M., Rothwell N.J., Brough D. The dynamics and mechanisms of interleukin-1 alpha and beta nuclear import // Traffic. 2009. Vol. 10. № 1. P. 16-25.
  106. Luheshi N.M., Rothwell N.J., Brough D. Dual functionality of interleukin-1 family cytokines: implications for anti-interleukin-1 therapy // Br. J. Pharmacol. 2009. Vol. 157. № 8. P. 1318-1329.
  107. Ma X.C. Gottschall P.E., Chen L.T. et al. Role and mechanisms of interleukin-1 in the modulation of neurotoxicity // Neuroimmunomodulation. 2002-2003. Vol. 10. № 4. P. 199-207.
  108. Maes M. Evidence for an immune response in major depression: a review and hypothesis // Prog. Neuropsychophannacol. Biol. Psychiatry. 1995. Vol. 19. № L P. 11-38.
  109. Maier S.F., Watkins L.R. Intracerebroventricular interleukin-1 receptor antagonist blocks the enhancement of fear conditioning and interference with escape produced by inescapable shock // Brain Res. 1995. Vol. 695. № 2. P. 279-282.
  110. Matsumoto M., Matsumoto K., Tanaka K. Effects of novelty on activity of lateral and medial prefrontal neurons // Neurosci. Res. 2007. Vol. 57. № 2. P. 268-276.
  111. Matsumoto Y., Yoshida M., Watanabe S., Yamamoto T. Involvement of cholinergic and glutamatergic functions in working memory impairment induced by interleukin-1 beta in rats // Eur. J. Pharmacol. 2001. Vol. 430. № 2-3. P. 283-288.
  112. Matta S.G., Linner K.M., Sharp B.M. Interleukin-1 alpha and interleukin-1 beta stimulate adrenocorticotropin secretion in the rat through a similar hypothalamic receptor(s): effects of interleukin-1 receptor antagonist protein // Neuroendocrinology. 1993. Vol. 57.№ I. P. 14-22.
  113. McCarley R.W. Neurobiology of REM and NREM sleep // Sleep Med. 2007. Vol. 8. № 4. P. 302-330.
  114. McHugh T.J., Tonegawa S. CA3 NMDA Receptors are Required for the Rapid Formation of a Salient Contextual Representation // Hippocampus. 2009. Vol. 19. № 12. P. 1153-1158.
  115. McLay R.N., Kastin A.J., Zadina J.E. Passage of lnterleukin-1-Beta Across the Blood-Brain Barrier Is Reduced in Aged Mice: A Possible Mechanism for Diminished Fever in Aging // Neuroimmunomodulation. 2000. Vol. 8. № 3. Р. 148-153.
  116. Millichap J.G. Etiologic classification of attention-deficit/hyperactivity disorder // Pediatrics. 2008. Vol. 121. №2. P. 358-365.
  117. Minagawa K., Tsuji Y., Ueda H. et al. Possible correlation between high levels of IL-18 in the cord blood of pre-term infants and neonatal development of periventricular leukomalacia and cerebral palsy // Cytokine. 2002. Vol. 17. № 3. P. 164-170.
  118. Minami M., Kuraishi Y., Yabuuchi K. et al. Induction of interleukin-1 beta mRNA in rat brain after transient forebrain ischemia // J. Neurochem. 1992. Vol. 58. №• 1. P. 390-392.
  119. Miyamoto S., LaMantia A.S., Duncan G.E. et al. Recent advances in the neurobiology of schizophrenia // Mol lnterv. 2003. Vol. 3. № 1. P. 27-39.
  120. Miyoshi K., Obata K., Kondo T. et al. Interleukin-18-mediated microglia/astrocyte interaction in the spinal cord enhances neuropathic pain processing after nerve injury /7 J. Neurosci. 2008. Vol. 28. № 48. P. 12775-12787.
  121. Mizuno T., Sawada M., Suzuinura A., Marunouchi T. Expression of cytokines during glial differentiation // Brain Res. 1994. Vol. 656. № 1. P. 141-146.
  122. Montero V.M., Wright L.S., Siegel F. Increased glutamate, GABA and glutamine in lateral geniculate nucleus but not in medial geniculate nucleus caused by visual attention to novelty // Brain Res. 2001.Vol. 916. № i-2. P. 152-158.
  123. Murray C.A., McGahon B., McBennett S., Lynch M.A. Interleukin-1 beta inhibits glutamate release in hippocampus of young, but not aged, rats // Neurobiol. Aging. 1997. Vol. 18. № 3. P. 343-348.
  124. Nagai Y., Watanabe K., Aso H. et al. Cellular localization of IL-18 and IL-18 receptor in pig anterior pituitary gland 7 Domest. Anim. Endocrinol. 2006. Vol. 30. №2. P. 144-154.
  125. Nagai Y., Ogasawara H., Taketa Y. et al. Bovine anterior pituitary progenitor cell line expresses interleukin (IL)-18 and 1L-18 receptor // J. Neuroendocrinol. 2008. Vol. 20. № 11. P. 1233-1241.
  126. Nieto-Sampedro M., Berman M.A. Interleukin-1-like activity in rat brain: sources, targets, and effect of injury // J. Neurosci. Res. 1987. Vol. 17. № 3. P. 214-219.
  127. Obal F. Jr., Krueger J.M. Biochemical regulation of non-rapid-eye-movement sleep // Front. Biosci. 2003. № 8. P. 520-550.
  128. Ohashi K., Saigusa T. Sympathetic nervous responses during cytokine-induced fever in conscious rabbits // Pflugers Arch. 1997. Vol. 433. № 6. P. 691-698.
  129. Oitzl M.S., van Oers H., Schöbitz В., de Kloet E.R. Interleukin-1 beta, but not interleukin-6, impairs spatial navigation learning // Brain Res. 1993. Vol. 613. № 1. P. 160-163.
  130. Okamura H., Tsuisi H., Komatsu T. et al. Cloning of a new cytokine that induces IFN-gamma production by T cells // Nature. 1995. Vol. 378. Xs 6552. P. 88-91.
  131. Palin K., Pousset F., Verrier D. et al. Characterization оГ interleukin-1 receptor antagonist isoform expression in the brain oflipopolysaccharide-treated rats // Neuroscience. 2001. Vol. 103. № 1. P. 161-169.
  132. Papa M., Pellicano M.P., Welzl H., Sadile A.G. Distributed changes in c-Fos and e-Jun immunoreactivity in the rat brain associated with arousal and habituation to novelty // Brain Res. Bull. 1993. Vol. 32. № 5. P. 509-515.
  133. Parish C.L., Finkeistein D.I., Tripanichkul W. et al. The role of interleukin-1, interleukin-6, and glia in inducing grow th of neuronal terminal arbors in mice J. Neurosci. 2002. Vol. 22. № 18. P. 8034-8041.
  134. Parker L.C., Luheshi G.N., Rothwell N.J., Pinteaux E. IL-Iβ signalling in glial cells in wildtype and IL-1RI deficient mice // Br. J. Pharmacol. 2002. Vol. 136. №2. P. 312-320.
  135. Parker L.C., Rushforth D.A., Rothwell N.J., Luheshi G.N. IL-lbeta induced changes in hypothalamic IL-1R1 and 1L-1R2 mRNA expression in the rat // Brain Res. Mol. Brain Res. 2000. Vol. 79. № 1-2. P. 156-158.
  136. Parnet P., Amindari S., Wu C. et al. Expression of type I and type II interleukin-1 receptors in mouse brain // Brain Res. Mol. Brain Res. 1994. Vol. 27. Xs 1. P. 63-70.
  137. Pearson V.L., Rothwell N.J., Toulmond S. Excitotoxic brain damage in the rat induces interleukin-1 beta protein in microglia and astrocytes: correlation with the progression of cell death // Glia. 1999. Vol. 25. № 4. P. ЗІ 1-323.
  138. Pinteaux E., Parker L.C., Rothwell N.J., Luheshi G.N. Expression of interleukin-1 receptors and their role in interleukin-1 actions in murine microglial cells // Neurochem. 2002. Vol. 83. X« 4. P. 754-763.
  139. Pousset F., Palin K., Verrier D. et al. Production of in-terleukin-1 receptor antagonist isoforms by microglia in mixed rat glial cells stimulated by lipopolysaccharide /7 Eur. Cytokine Netw. 2000. Vol. 11. X» 4. P. 682-689.
  140. Prinz M., Hanisch U.K. Murine microglial cells produce and respond to interleukin-18 // Neurochem. 1999. Vol. 72. № 5. P. 2215-2218.
  141. Quan N., Whiteside M., Herkenham M. Time course and localization patterns of interleukin-1 beta messenger RNA expression in brain and pituitary after peripheral administration of lipopolysaccharide // Neuroscience. 1998. Vol. 83. № 1. P. 281-293.
  142. Rada P., Mark G.P., Vitek M.P. et al. Interleukin-lβ decreases acetylcholine measured by microdialysis in the hippocampus of freely moving rats // Brain Res. 1991. Vol. 550 № 2. P. 287-290.
  143. Reu! J.M., Stec I., Wiegers G.J. et al. Prenatal immune challenge alters the hypothalamic-pituitary-adrenocortical axis in adult rats // J. Clin. Invest. 1994. Vol. 93. X» 6. P. 2600-2607.
  144. Rice D., Barone S. Jr. Critical periods of vulnerability for the developing nervous system: evidence from hu mans and animal models // Environ. Health Perspect. 2000. № 108. P. 511-533.
  145. Romero E., Guaza C., Castellano B., Borrell J. Ontogeny of sensorimotor gating and immune impairment induced by prenatal immune challenge in rats: implications for the etiopathology of schizophrenia // Mol. Psychiatry. 2010. Vol. 14. Xs 4. P. 372-383.
  146. Saindon C.S., Blccha F., Musch T.l. et al. Effect of con ical vagotomy on sympathetic nerve responses to peripheral interleukin-1 beta//Auton. Neurosci. 2001. Vol. 87. Xs 2-3. P. 243-248.
  147. Salter M.W., Kalia L.V. Src kinases: a hub for NMDA receptor regulation // Nat. Rev. Neurosci. 2004. Vol. 5. № 4. P. 317-328.
  148. Sama M.A., Mathis D.M., Furman J.L. et al. Interleukin1 beta-dependent signaling between astrocytes and neurons depends critically on astrocytic calcineurin // NFAT activity. J. Biol. Chem. 2008. Vol. 283. X« 32. P. 21953-21964.
  149. Sanderson K.L., Raghupathi R., Saatman K.E. et al. Interleukin-1 receptor antagonist attenuates regional neuronal cell death and cognitive dysfunction after experimental brain injury // Cereb. Blood Flow Metab. 1999. Vol. I9.Xs 10. P. 1118-1125.
  150. Schott B.H., Sellner D.B., Lauer C.J. et al. Activation of midbrain structures by associative novelty and the formation of explicit memory in humans // Leant. Mem. 2004. Vol. 11. Xs 4. P. 383-387.
  151. Segrnan R.H., Meitzer A., Gross-Tsur V. et al. Preferential transmission of interleukin-1 receptor antagonist alleles in attention deficit hyperactivity disorder // Mol. Psychiatry. 2002. Vol. 7. Xs 1. P. 72-74.
  152. Serantes R., Amalich F., Figueroa M. et al. Interleukin1 beta enhances GABAA receptor cell-surface expression by a phosphatidylinositol 3-kinase. Akt pathway: relevance to sepsis-associated encephalopathy // J. Biol. Chem. 2006. Vol. 281. Xs 21. P. 14632-14643.
  153. Skinner R.A., Gibson R.M., Rothw'ell N.J. et al. Transport of interleukin-1 across cerebromicrovascular endothelial cells // Br. J. Phannacol. 2009. Vol. 156. № 7. P. 1115-1123.
  154. Smith R.S. The macrophage theory of depression // Med. Hypotheses. 1991. Vol. 35. № 4. P. 298-306.
  155. Song C., Phillips A.G., Leonard B. Interleukin 1 beta enhances conditioned fear memory in rats: possible involvement of glucocorticoids // Eur. J. Neurosci. 2003. Vol. 18. № 7. P. 1739-1743.
  156. Spadaro F., Dunn A. J. Intracerebroventricular administration of intcrleukin-l to mice alters investigation of stimuli in a novel environment // Brain Behav. Immunol. 1990. Vol. 4. Xs 4. P. 308-322.
  157. Spadaro F., Dunn A.J. Intracerebroventricular administration of interleukin-1 to mice alters investigation of stimuli in a novel environment Brain Behav. Immunol. 1990. Vol. 4. Xs 4. P. 308-322.
  158. Spulber S., Mateos L., Oprica M. et al. Impaired long term memory' consolidation in transgenic mice overexpressing the human soluble fonn of IL-lra in the brain // J. Neuroimmunol. 2009. Vol. 208. № 1-2. P. 46-53.
  159. Srinivasan D., Yen J.H., Joseph D.J., Friedman W. Cell Type-Specific Interleukin-1 beta Signaling in the CNS // J. Neurosci. 2004. Vol. 24. Ns 29. P. 6482-6488.
  160. Stuyt R.J., Netea M.G., Verschueren I. et al. Interleukin-18 does not modulate the acute-phase response ii J. Endotoxin Res. 2005. Vol. 11. № 2. P. 85-88.
  161. Taepavarapruk P., Song C. Reductions of acetylcholine release and nerve growth factor expression are correlated with memory impairment induced by interleukin-1 beta administrations: effects of omega-3 fatty acid EPA treatment // J. Neurochem. 2010. Vol. 112. №4. P. 1054-1064.
  162. Takao T., Nagano I., Tojo C. et al. Age-related reciprocal modulation of interleukin-1 beta and interleukin1 receptors in the mouse brain-endocrine-immune axis // Neuroimmunomodulation. 1996. Vol. 3. № 4. P. 205-212.
  163. Takao T., Tracey D.E., Mitchell W.M., De Souza E.B. Interleukin-1 Receptors in Mouse Brain: Characterization and Neuronal Localization // Endocrinology. 1990. Vol. 127. № 6. P. 3070-3078.
  164. Tanaka S., Kamitani H., Hori T. et al. [Interleukin 1 and gliomas: immunohistochemical and immunocytochemical examinations // No To Shinkei. 1988. Vol. 40. №3. P 205-210.
  165. Tazi A., Dantzer R., Crestani F., Le Moal M. lnterleukin-1 induces conditioned taste aversion in rats: a possible explanation for its pituitary-adrenal stimulating activity // Brain Res. 1988. Vol. 473. Ns 2. P. 369-371Г
  166. Tohmi M., Tsuda N., Zheng Y. et al. The cellular and behavioral consequences of interleukin-1 alpha penetration through the blood-brain barrier of neonatal rats: a critical period for efficacy // Neuroscience. 2007. Vol. 150. № 1. P. 234-250.
  167. Tsakiri N., Kimber L., Rothwell N.J., Pinteaux E. Differential effects of interleukin-1 alpha and beta on interleukin-6 and chemokine synthesis in neurons // Mol. Cell. Neurosci. 2008. Vol. 38. № 2. P. 259-265.
  168. Utsuyama M., Hirokawa K. Differential expression of various cytokine receptors in the brain after stimulation with LPS in young and old mice it Exp. Gerontol. 2002. Vol. 37. № 2-3. P. 411-420.
  169. Vago D.R., Kesner R.P. Disruption of the direct perforant path input to the CA1 subregion of the dorsal hippocampus interferes with spatial working memory and novelty detection /! Behav. Brain Res. 2008. Vol. 189. № 2. P. 273-283.
  170. Vela J.M., Molina-Holgado E., Arévalo-Martin A. et al. Interleukin-1 regulates proliferation and differentiation of oligodendrocyte progenitor cells // Mol. Cell. Neurosci. 2002. Vol. 20. № 3. P. 489-502.
  171. Vitkovic L., Bockaert J., Jacque C. «Inflammatory» cytokines: neuromodulators in normal brain? // J. Neurochem. 2000. Vol. 74. № 2. P. 457-471.
  172. Wang S., Yan J.Y., Lo Y.K., Carvey P.M. et al. Dopaminergic and serotoninergic deficiencies in young adult rats prenatally exposed to the bacterial lipopolysaccharide /7 Brain Res. 2009. № 1265. P. 196-204.
  173. Wang X.F., Yin L., Hu J.G. et al. Expression and localization of p80 interleukin-1 receptor protein in the rat spinal cord // J. Mol. Neurosci. 2006. Vol. 29. № 1. P. 45-53.
  174. Watkins L.R., Goehler L.E., Relton J.K. et al. Blockade of interleukin-1 induced hyperthermia by subdi-aphragmatic vagotomy: evidence for vagal mediation of immune-brain communication //Neurosci. Lett. 1995. Vol. 183. № 1-2. P. 27-31.
  175. Wheeler R.D., Culhane A.C., Hall M.D. et al. Detection of the interleukin 18 family in rat brain by RT-PCR // Brain Res. Mol. Brain Res. 2000. Vol. 77. № 2. P. 290-293.
  176. Wieczorek M., Swiergiel A.H., Poumajafi-Nazarioo H., Dunn A.J. Physiological and behavioral responses to interleukin-1 beta and LPS in vagotomized mice // Physiol. Behav. 2005. Vol. 85. № 4. P. 500-511.
  177. Wieczorek M., Dunn A.J. Effect of subdiaphragmatic vagotomy on the noradrenergic and HPA axis activation induced by intraperitoneal interleukin-1 administration in rats // Brain Res. 2006. Vol. 1101. № I. P. 73-84.
  178. Wong M.L., Licinio J. Localization of interleukin 1 type 1 receptor mRNA in rat brain // Neuroimmunomodulation. 1994. Vol. l.№2. P. 110-115.
  179. Xiaoqin Z., Zhengli L., Changgeng Z. et al. Changes in behavior and amino acid neurotransmitters in the brain of rats with seizure induced by IL-lbeta or IL-6 // J. Huazhong Univ. Sei. Technolog. Med. Sci. 2005. Vol. 25. Ns 3. P. 236-239.
  180. Yaguchi T., Nagata T., Yang D., Nishizaki T. Interleukin-18 regulates motor activity, anxiety and spatial learning without affecting synaptic plasticity // Behav. Brain Res. 2010. Vol. 206. № 1. P. 47-51.
  181. Yamasaki Y., Matsuura N., Shozuhara H. et al. Interleukin-1 as a pathogenetic mediator of ischemic brain damage in rats // Stroke. 1995. Vol. 26. Ns 4. P. 676-680.
  182. Yirmiya R., Avitsur R., Donchin O., Cohen E. Interleukin-1 inhibits sexual behavior in female but not in male rats i! Brain Behav. Immunol. 1995. Vol. 9. Ns 3. P. 220-233.
  183. Yirmiya R., Winocur G., Goshen I. Brain interleukin-1 is involved in spatial memory' and passive avoidance conditioning // Neurobiol. Learn. Mem. 2002. Vol. 78.№ 2. P. 379-389.
  184. Yoon B.H., Jun J.K., Romero R. et al. Amniotic fluid inflammatory cytokines (interleukin-6, interleukin-lbeta, and tumor necrosis factor-alpha), neonatal brain white matter lesions, and cerebral palsy // Am. J. Obstet Gynecol. 1997. Vol. 177. № I. P. 19-26.
  185. Zalcman S., Green-Johnson J.M., Murray L. et al. Cytokine-specific central monoamine alterations induced by interleukin-1, -2 and -6 // Brain Res. 1994. Vo). 643. № 1-2. P. 40-49.
  186. Zhang W., Smith C., Howlett C., Stanimirovic D. Inflammatory activation of human brain endothelial cells by hypoxic astrocytes in vitro is mediated by IL-lbeta // Cereb. Blood Flow. Metab. 2000. Vol. 20. № 6. P. 967-978.
  187. Zubareva O.E., Krasnova I.N., Abdurasulova I.N. et al. Effects of serotonin synthesis blockade on interleukin-lβ action in the brain of rats // Brain Res. 2001. Vol. 915. № 2. P. 244-247.

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